Search Results - "Sabeh, M. Khaled"

The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion by Wang, Jinhu, Panáková, Daniela, Kikuchi, Kazu, Holdway, Jennifer E, Gemberling, Matthew, Burris, James S, Singh, Sumeet Pal, Dickson, Amy L, Lin, Yi-Fan, Sabeh, M Khaled, Werdich, Andreas A, Yelon, Deborah, Macrae, Calum A, Poss, Kenneth D

“…Natural models of heart regeneration in lower vertebrates such as zebrafish are based on invasive surgeries causing mechanical injuries that are limited in…”
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Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of PRDM16 as a Cause of Cardiomyopathy by Arndt, Anne-Karin, Schafer, Sebastian, Drenckhahn, Jorg-Detlef, Sabeh, M. Khaled, Plovie, Eva R., Caliebe, Almuth, Klopocki, Eva, Musso, Gabriel, Werdich, Andreas A., Kalwa, Hermann, Heinig, Matthias, Padera, Robert F., Wassilew, Katharina, Bluhm, Julia, Harnack, Christine, Martitz, Janine, Barton, Paul J., Greutmann, Matthias, Berger, Felix, Hubner, Norbert, Siebert, Reiner, Kramer, Hans-Heiner, Cook, Stuart A., MacRae, Calum A., Klaassen, Sabine

“…Deletion 1p36 syndrome is recognized as the most common terminal deletion syndrome. Here, we describe the loss of a gene within the deletion that is…”
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Chamber identity programs drive early functional partitioning of the heart by Mosimann, Christian, Panáková, Daniela, Werdich, Andreas A., Musso, Gabriel, Burger, Alexa, Lawson, Katy L., Carr, Logan A., Nevis, Kathleen R., Sabeh, M. Khaled, Zhou, Yi, Davidson, Alan J., DiBiase, Anthony, Burns, Caroline E., Burns, C. Geoffrey, MacRae, Calum A., Zon, Leonard I.

“…The vertebrate heart muscle (myocardium) develops from the first heart field (FHF) and expands by adding second heart field (SHF) cells. While both lineages…”
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The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart by Werdich, Andreas A., Brzezinski, Anna, Jeyaraj, Darwin, Khaled Sabeh, M., Ficker, Eckhard, Wan, Xiaoping, McDermott, Brian M., MacRae, Calum A., Rosenbaum, David S.

“…Altered mechanical loading of the heart leads to hypertrophy, decompensated heart failure and fatal arrhythmias. However, the molecular mechanisms that link…”
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Saphenous Vein Graft Aneurysm Presenting as Abdominal Pain by Baydoun, Atallah, MD, Sabeh, M. Khaled, MD, Abdul Rahman, Rania, MD, Park, Soon J., MD, Parikh, Sahil A., MD

“…Aneurysmal dilation of a saphenous vein aortocoronary graft remains a rare complication. We report a patient with saphenous vein graft aneurysm who presented…”
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Kruppel-like factors in muscle health and disease by Prosdocimo, Domenick A., PhD, Sabeh, M. Khaled, MD, Jain, Mukesh K., MD

“…Abstract Kruppel-like factors (KLF) are zinc-finger DNA-binding transcription factors that are critical regulators of tissue homeostasis. Emerging evidence…”
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Optical Mapping in the Developing Zebrafish Heart by Sabeh, M. Khaled, Kekhia, Hussein, MacRae, Calum A.

“…Understanding the developmental basis of cardiac electrical activity has proven technically challenging, largely as a result of the inaccessible nature of the…”
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Left Atrial Volume Index Is Associated With Cardioembolic Stroke and Atrial Fibrillation Detection After Embolic Stroke of Undetermined Source by Jordan, Kevin, Yaghi, Shadi, Poppas, Athena, Chang, Andrew D, Mac Grory, Brian, Cutting, Shawna, Burton, Tina, Jayaraman, Mahesh, Tsivgoulis, Georgios, Sabeh, M Khaled, Merkler, Alexander E, Kamel, Hooman, Elkind, Mitchell S.V, Furie, Karen, Song, Christopher

“…BACKGROUND AND PURPOSE—Left atrial enlargement has been shown to be associated with ischemic stroke, but the association with embolic stroke mechanisms remains…”
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Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish by Wythe, Joshua D, Jurynec, Michael J, Urness, Lisa D, Jones, Christopher A, Sabeh, M Khaled, Werdich, Andreas A, Sato, Mariko, Yost, H Joseph, Grunwald, David J, Macrae, Calum A, Li, Dean Y

“…The vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued embryonic development. Here we…”
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REDUCTION IN CARDIOVASCULAR MORTALITY AMONG SURVIVORS OF CHILDHOOD LYMPHOID CANCERS IN THE UNITED STATES by Al-Kindi, Sadeer G, Kim, Chang, Farhoud, Mahmoud, Sabeh, M. Khaled, Rhea, Isaac, Wilson, Jamie, Lewis, Monica, Oliveira, Guilherme

“…Methods We used SEER 18 database to identify all children who were diagnosed with lymphoid malignancies (lymphoma or acute lymphoid leukemia) from 1973-2012…”
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Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization by MILAN, David J, KIM, Albert M, ROSENBAUM, David S, PETERSON, Randall T, CHAKRAVARTI, Aravinda, KÄÄB, Stefan, RODEN, Dan M, MACRAE, Calum A, WINTERFIELD, Jeffrey R, JONES, Ian L, PFEUFER, Arne, SANNA, Serena, ARKING, Dan E, AMSTERDAM, Adam H, SABEH, Khaled M, MABLY, John D

“…Cardiac repolarization, the process by which cardiomyocytes return to their resting potential after each beat, is a highly regulated process that is critical…”
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The genetics of atrial fibrillation by Sabeh, M Khaled, MacRae, Calum A

“…PURPOSE OF REVIEWA substantial genetic contribution to the etiology of atrial fibrillation has emerged in the last decade, and has bolstered links between this…”
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Novel Use of a Rotating Mechanical Dilator Sheath for S-ICD Lead Extraction by Allison, John D., Sabeh, M. Khaled, Mela, Theofanie

“…A 53-year-old man with a subcutaneous implantable cardioverter-defibrillator (S-ICD) presented with inappropriate shocks. He underwent device extraction, and…”
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Left Atrial Volume Index is Associated with Cardioembolic Stroke and Atrial Fibrillation Detection after ESUS by Jordan, Kevin, Yaghi, Shadi, Poppas, Athena, Chang, Andrew D., Grory, Brian Mac, Cutting, Shawna, Burton, Tina, Jayaraman, Mahesh, Tsivgoulis, Georgios, Sabeh, M. Khaled, Merkler, Alexander, Kamel, Hooman, Elkind, Mitchell S. V., Furie, Karen, Song, Christopher

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Novel Use of a Rotating Mechanical Dilator Sheath for S-ICD Lead Extraction by Allison, John D, Sabeh, M Khaled, Mela, Theofanie

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