Search Results - "Sabedot, Thais"

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data by Colaprico, Antonio, Silva, Tiago C, Olsen, Catharina, Garofano, Luciano, Cava, Claudia, Garolini, Davide, Sabedot, Thais S, Malta, Tathiane M, Pagnotta, Stefano M, Castiglioni, Isabella, Ceccarelli, Michele, Bontempi, Gianluca, Noushmehr, Houtan

“…The Cancer Genome Atlas (TCGA) research network has made public a large collection of clinical and molecular phenotypes of more than 10 000 tumor patients…”
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Glioma progression is shaped by genetic evolution and microenvironment interactions by Varn, Frederick S., Johnson, Kevin C., Martinek, Jan, Huse, Jason T., Wesseling, Pieter, Cooper, Lee A.D., Malta, Tathiane M., Wade, Taylor E., Brat, Daniel, Aldape, Kenneth, Ismail, Azzam, Kim, Hoon, White, Kieron, Pollock, Steven, Goldfarb, Christine, Lee, Ga-Hyun, Anderson, Kevin J., Nehar-Belaid, Djamel, Bakas, Spyridon, Byrne, Annette T., D’Angelo, Fulvio, Gan, Hui K., Khasraw, Mustafa, Migliozzi, Simona, Paek, Sun Ha, Walenkamp, Annemiek M.E., Weiss, Tobias, Poisson, Laila M., Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel G.W., Varn, Frederick S., Huse, Jason T., Nasrallah, MacLean P., Wesseling, Pieter, Cooper, Lee A.D., Malta, Tathiane M., Sabedot, Thais S., Brat, Daniel, Gould, Peter V., Aldape, Kenneth, Sivajothi, Santhosh K., Barthel, Floris P., Kocakavuk, Emre, Ahmed, Nazia, White, Kieron, Moon, Hyo-Eun, Pollock, Steven, Lee, Ga-Hyun, Garofano, Luciano, Anderson, Kevin J., Nehar-Belaid, Djamel, Barnholtz-Sloan, Jill S., Bakas, Spyridon, Byrne, Annette T., Gan, Hui K., Khasraw, Mustafa, Ryan Ormond, D., Ha Paek, Sun, Van Meir, Erwin G., Walenkamp, Annemiek M.E., Watts, Colin, Weiss, Tobias, Weller, Michael, Amin, Samirkumar B., Brodbelt, Andrew, Bulsara, Ketan R., Castro, Ana Valeria, Connelly, Jennifer M., Costello, Joseph F., Finocchiaro, Gaetano, French, Pim J., Hau, Ann C., Hong, Chibo, Horbinski, Craig, Kannan, Kasthuri S., Kouwenhoven, Mathilde CM, LaViolette, Peter S., Ligon, Keith L., Lowman, Allison K., Miletic, Hrvoje, Niers, Johanna M., Phillips, Joanna J., Rabadan, Raul, Rao, Ganesh, Reifenberger, Guido, Sanai, Nader, Short, Susan C., Suzuki, Hiromichi, Tabatabai, Ghazaleh, Tomaszewski, William H., Wells, Michael, Wheeler, Helen, Xie, Jichun, Alfred Yung, W.K., Zadeh, Gelareh, Poisson, Laila M., Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel GW

“…The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed…”
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Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications by Malta, Tathiane M, de Souza, Camila F, Sabedot, Thais S, Silva, Tiago C, Mosella, Maritza S, Kalkanis, Steven N, Snyder, James, Castro, Ana Valeria B, Noushmehr, Houtan

“…Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical properties. Despite advances in surgical techniques and clinical…”
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A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence by de Souza, Camila Ferreira, Sabedot, Thais S., Malta, Tathiane M., Stetson, Lindsay, Morozova, Olena, Sokolov, Artem, Laird, Peter W., Wiznerowicz, Maciej, Iavarone, Antonio, Snyder, James, deCarvalho, Ana, Sanborn, Zachary, McDonald, Kerrie L., Friedman, William A., Tirapelli, Daniela, Poisson, Laila, Mikkelsen, Tom, Carlotti, Carlos G., Kalkanis, Steven, Zenklusen, Jean, Salama, Sofie R., Barnholtz-Sloan, Jill S., Noushmehr, Houtan

“…Glioma diagnosis is based on histomorphology and grading; however, such classification does not have predictive clinical outcome after glioblastomas have…”
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Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas by Kocakavuk, Emre, Johnson, Kevin C, Sabedot, Thais S, Reinhardt, Hans Christian, Noushmehr, Houtan, Verhaak, Roel G W

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RGBM: regularized gradient boosting machines for identification of the transcriptional regulators of discrete glioma subtypes by Mall, Raghvendra, Cerulo, Luigi, Garofano, Luciano, Frattini, Veronique, Kunji, Khalid, Bensmail, Halima, Sabedot, Thais S, Noushmehr, Houtan, Lasorella, Anna, Iavarone, Antonio, Ceccarelli, Michele

“…Abstract We propose a generic framework for gene regulatory network (GRN) inference approached as a feature selection problem. GRNs obtained using Machine…”
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A serum-based DNA methylation assay provides accurate detection of glioma by Sabedot, Thais S, Malta, Tathiane M, Snyder, James, Nelson, Kevin, Wells, Michael, deCarvalho, Ana C, Mukherjee, Abir, Chitale, Dhananjay A, Mosella, Maritza S, Sokolov, Artem, Asmaro, Karam P, Robin, Adam, Rosenblum, Mark L, Mikkelsen, Tom, Rock, Jack, Poisson, Laila M, Lee, Ian, Walbert, Tobias, Kalkanis, Steven, Iavarone, Antonio, Castro, Ana Valeria, Noushmehr, Houtan

“…Abstract Background The detection of somatic mutations in cell-free DNA (cfDNA) from liquid biopsy has emerged as a noninvasive tool to monitor the follow-up…”
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The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen by Malta, Tathiane M, Sabedot, Thais S, Morosini, Natalia S, Datta, Indrani, Garofano, Luciano, Vallentgoed, Wies, Varn, Frederick S, Aldape, Kenneth, D'Angelo, Fulvio, Bakas, Spyridon, Barnholtz-Sloan, Jill S, Gan, Hui K, Hasanain, Mohammad, Hau, Ann-Christin, Johnson, Kevin C, Cazacu, Simona, deCarvalho, Ana C, Khasraw, Mustafa, Kocakavuk, Emre, Kouwenhoven, Mathilde C M, Migliozzi, Simona, Niclou, Simone P, Niers, Johanna M, Ormond, D Ryan, Paek, Sun Ha, Reifenberger, Guido, Sillevis Smitt, Peter A, Smits, Marion, Stead, Lucy F, van den Bent, Martin J, Van Meir, Erwin G, Walenkamp, Annemiek, Weiss, Tobias, Weller, Michael, Westerman, Bart A, Ylstra, Bauke, Wesseling, Pieter, Lasorella, Anna, French, Pim J, Poisson, Laila M, Verhaak, Roel G W, Iavarone, Antonio, Noushmehr, Houtan

“…Tumor adaptation or selection is thought to underlie therapy resistance in glioma. To investigate longitudinal epigenetic evolution of gliomas in response to…”
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Detection of tumor-specific DNA methylation markers in the blood of patients with pituitary neuroendocrine tumors by Herrgott, Grayson A, Asmaro, Karam P, Wells, Michael, Sabedot, Thais S, Malta, Tathiane M, Mosella, Maritza S, Nelson, Kevin, Scarpace, Lisa, Barnholtz-Sloan, Jill S, Sloan, Andrew E, Selman, Warren R, deCarvalho, Ana C, Poisson, Laila M, Mukherjee, Abir, Robin, Adam M, Lee, Ian Y, Snyder, James, Walbert, Tobias, Rosenblum, Mark, Mikkelsen, Tom, Bhan, Arti, Craig, John, Kalkanis, Steven, Rock, Jack, Noushmehr, Houtan, Castro, Ana Valeria

“…Abstract Background DNA methylation abnormalities are pervasive in pituitary neuroendocrine tumors (PitNETs). The feasibility to detect methylome alterations…”
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DNA methylation-based signatures classify sporadic pituitary tumors according to clinicopathological features by Mosella, Maritza S, Sabedot, Thais S, Silva, Tiago C, Malta, Tathiane M, Dezem, Felipe Segato, Asmaro, Karam P, Wells, Michael, Mukherjee, Abir, Poisson, Laila M, Snyder, James, deCarvalho, Ana C, Walbert, Tobias, Aho, Todd, Kalkanis, Steven, Elias, Paula C, Antonini, Sonir R, Rock, Jack, Noushmehr, Houtan, Castro, Margaret, Castro, Ana Valeria

“…Abstract Background Distinct genome-wide methylation patterns cluster pituitary neuroendocrine tumors (PitNETs) into molecular groups associated with specific…”
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SIRT1 regulates Mxd1 during malignant melanoma progression by Meliso, Fabiana M, Micali, Danilo, Silva, Camila T, Sabedot, Thaís S, Coetzee, Simon G, Koch, Adrian, Fahlbusch, Fabian B, Noushmehr, Houtan, Schneider-Stock, Regine, Jasiulionis, Miriam G

“…In a murine melanoma model, malignant transformation promoted by a sustained stress condition was causally related to increased levels of reactive oxygen…”
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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma by Ceccarelli, Michele, Salama, Sofie R., Manyam, Ganiraju, Zoppoli, Pietro, Grifford, Mia, Rao, Arvind, Lau, Ching C., Huse, Jason, Zheng, Siyuan, Hess, Kenneth, Rao, Ganesh, Beroukhim, Rameen, Akbani, Rehan, Wrensch, Margaret, Haussler, David, Aldape, Kenneth D., Anjum, Samreen, Balu, Saianand, Barnett, Gene, Black, Keith L., Bristow, Christopher A., Chen, Qing-Rong, Cho, Juok, Chuah, Eric, Chudamani, Sudha, Cohen, Mark L., Couce, Marta, Davidsen, Tanja, Davis, Amy, Elder, J. Bradley, Eschbacher, Jennifer M., Fehrenbach, Ashley, Ferguson, Martin, Fuller, Gregory, Fulop, Jordonna, Garofano, Luciano, Gastier-Foster, Julie M., Gehlenborg, Nils, Gerken, Mark, Gibson, William J., Hadjipanayis, Angela, Hayes, D. Neil, Hilty, Joe, Hoyle, Alan P., Jones, Corbin D., Jones, Steven J.M., Ju, Zhenlin, Kastl, Alison, Kendler, Ady, Kucherlapati, Raju, Lichtenberg, Tara M., Lin, Pei, Ljubimova, Julia Y., Lu, Yiling, Ma, Yussanne, Maglinte, Dennis T., Marra, Marco A., Meng, Shaowu, Miller, C. Ryan, Mills, Gordon B., Mose, Lisle E., Naska, Theresa, Noble, Michael S., Noss, Ardene, Palmer, Cheryl, Parfenov, Michael, Parker, Joel S., Perou, Charles M., Pihl, Todd, Protopopov, Alexei, Ramirez, Nilsa C., Saksena, Gordon, Schein, Jacqueline E., Shen, Hui, Shi, Yan, Shimmel, Kristen, Sicotte, Hugues, Sifri, Suzanne, Silva, Tiago, Singh, Rosy, Song, Xingzhi, Souza, Camila, Sun, Huandong, Sun, Charlie, Tang, Jiabin, Trevisan, Felipe Amstalden, Van Den Berg, David J., Voet, Doug, Wang, Zhining, Weinstein, John N., Weisenberger, Daniel J., Wilkerson, Matthew D., Williams, Felicia, Wise, Lisa, Xu, Andrew W., Yang, Lixing, Zack, Travis I., Zhang, Jianhua, Zhang, Wei, Zmuda, Erik

“…Therapy development for adult diffuse glioma is hindered by incomplete knowledge of somatic glioma driving alterations and suboptimal disease classification…”
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Abstract 2085: The evolutionary trajectory of epigenomics in adult glioma by Datta, Indrani, Malta, Tathi, Sabedot, Thais, She, Ruicong, Iavarone, Antonio, Noushmehr, Houtan, Poisson, Laila M.

“…Abstract Background: Glioma is the most common malignant tumor of the central nervous system, often behaving very aggressively. Recently, The Cancer Genome…”
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EPCO-44. HOXD13 GENE PLAYS A ROLE AS A PUTATIVE MASTER EPIGENETIC REGULATOR IN GLIOMA RECURRENCE AND PROGRESSION by Morosini, Natalia, Sabedot, Thais, Cazacu, Simona, de Carvalho, Ana, Iavarone, Antonio, Noushmehr, Houtan

“…Abstract BACKGROUND Adult diffuse glioma is a heterogenous brain tumor group that has malignant potential and recurring properties. Glioma CpG island…”
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GENE-58. ACTIVE TRANSCRIPTION START SITES OF MENINGIOMA SAMPLES ASSOCIATED WITH RISK OF RECURRENCE by Malta, Tathiane, Sarraf Sabedot, Thais, Carlotti jr, Carlos, Noushmehr, Houtan

“…Abstract Meningiomas are mostly benign brain tumors but have a substantial risk of recurrence, sometimes to more aggressive subtypes. Recently, a DNA…”
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Abstract 2717: Glioma immune microenvironment change during tumor recurrence by Malta, Tathiane Maistro, Datta, Indrani, Sabedot, Thais, She, Ruicong, Castro, AnaValeria, Iavarone, Antonio, Poisson, Laila M., Noushmehr, Houtan

“…Abstract Background: Gliomas are the most common malignant brain tumor, have a very aggressive behavior, and invariably relapse and progress. Despite the…”
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Abstract 1640: Deep learning classification of neuro-oncology medical documents by Wells, Michael, Sabedot, Thais, Malta, Tathiane, Snyder, James, Poisson, Laila, Noushmehr, Houtan

“…Abstract Introduction Precision medicine and big data for cancer discovery requires well curated indexed critical health care data, however to date limited…”
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Abstract A12: DNA methylation-based liquid biopsy detects primary and recurrent meningioma by Sabedot, Thais S., Malta, Tathiane M., Snyder, James, Walbert, Tobias, Lee, Ian, Kalkanis, Steven, Castro, Ana Valeria, Noushmehr, Houtan

“…Abstract Meningiomas are mostly benign CNS tumors; however, a subset of these tumors may become atypical or malignant. The standard of care to monitor patients…”
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GENE-56. DEPLETION OF 5-HYDROXYMETHYLCYTOSINE IN AGGRESSIVE G-CIMP SUBTYPE by Sabedot, Thais Sarraf, Poisson, Laila, deCarvalho, Ana C, Noushmehr, Houtan

“…5-hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine, a reaction potentially mediated by the Tet family of enzymes. Levels of 5hmC were…”
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Abstract 907: Bioinformatic method to define epigenetically regulated enhancer elements associated with cancer by Sabedot, Thais S., Cassel, Seth H., Gao, Galen F., Lareau, Caleb A., Cherniack, Andrew, Lazar, Alexander, Kadoch, Cigall, Noushmehr, Houtan

“…Abstract BACKGROUND: Several mechanisms involved in gene regulation are altered in cancer. Cataloging these alterations can lead to a better understanding of…”
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