Search Results - "Sabbaghi, MohammadA"
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Defective Cyclin B1 Induction in Trastuzumab-emtansine (T-DM1) Acquired Resistance in HER2-positive Breast Cancer
Published in Clinical cancer research (15-11-2017)“…Trastuzumab-emtansine (T-DM1) is a standard treatment in advanced HER2-positive breast cancer. However, resistance inevitably occurs. We aimed to identify…”
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Targeted metabolomics in formalin-fixed paraffin-embedded tissue specimens: Liquid chromatography-tandem mass spectrometry determination of acidic metabolites in cancer research
Published in Talanta (Oxford) (01-02-2021)“…Formalin-fixed paraffin-embedded (FFPE) tissues play an irreplaceable role in cancer research. Although extensive research has been conducted for the detection…”
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Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer
Published in Clinical cancer research (15-09-2021)“…To characterize expression of neuregulin-1 (NRG1), an HER3 ligand, in HER2-positive breast cancer and its relation with the efficacy of trastuzumab with or…”
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Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma
Published in British journal of cancer (26-07-2016)“…Background: NF- κ B signalling appears deregulated in breast tumours. The purpose of this study was to determine whether the non-canonical NF- κ B pathway, is…”
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Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer
Published in European journal of cancer (1990) (01-10-2014)“…Abstract Aim Poly (ADP-ribose) polymerase (PARP) inhibitors have shown promising results in Breast Cancer (BRCA) deficient breast cancer, but not in…”
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Non-canonical NF-[kappa]B pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma
Published in British journal of cancer (26-07-2016)“…Background:NF-κB signalling appears deregulated in breast tumours. The purpose of this study was to determine whether the non-canonical NF-κB pathway, is…”
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Effect of trastuzumab on the antiproliferative effects of PI3K inhibitors in HER2+ breast cancer cells with de novo resistance to trastuzumab
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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mTOR inhibition and trastuzumab-emtansine (T-DM1) in HER2-positive breast cancer
Published in Molecular cancer research (29-03-2022)“…In patients with trastuzumab-resistant HER2-positive breast cancer, the combination of everolimus (mTORC1 inhibitor) with trastuzumab failed to show a…”
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IL-17A concentration of seminal plasma and follicular fluid in infertile men and women with various clinical diagnoses
Published in Immunological investigations (01-01-2014)“…Seminal plasma and follicular fluid (FF) cytokine analysis are valuable tools for diagnoses and validation of therapeutic approaches for improving the chance…”
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