Search Results - "Sabbagh, Ahmad"

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes by Eyres, Michael, Lanfredini, Simone, Xu, Haonan, Burns, Adam, Blake, Andrew, Willenbrock, Frances, Goldin, Robert, Hughes, Daniel, Hughes, Sophie, Thapa, Asmita, Vavoulis, Dimitris, Hubert, Aline, D’Costa, Zenobia, Sabbagh, Ahmad, Abraham, Aswin G., Blancher, Christine, Jones, Stephanie, Verrill, Clare, Silva, Michael, Soonawalla, Zahir, Maughan, Timothy, Schuh, Anna, Mukherjee, Somnath, O’Neill, Eric

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by advanced disease stage at presentation, aggressive disease biology, and resistance to therapy,…”
Get full text

Development of biosimilars by AL-Sabbagh, Ahmad, MD, Olech, Ewa, MD, McClellan, Joseph E., PhD, MBA, Kirchhoff, Carol F., PhD

“…Abstract Objective To provide an overview of the underlying scientific principles and standards for developing a biosimilar product. Methods An Internet-based…”
Get full text

The safety of activated eptacog beta in the management of bleeding episodes and perioperative haemostasis in adult and paediatric haemophilia patients with inhibitors by Escobar, Miguel, Castaman, Giancarlo, Boix, Santiago Bonanad, Callaghan, Michael, Moerloose, Philippe, Ducore, Jonathan, Hermans, Cédric, Journeycake, Janna, Leissinger, Cindy, Luck, James, Mahlangu, Johnny, Miesbach, Wolfgang, Mitha, Ismail Haroon, Négrier, Claude, Quon, Doris, Recht, Michael, Schved, Jean François, Shapiro, Amy D., Sidonio, Robert, Srivastava, Alok, Stasyshyn, Oleksandra, Vilchevska, Kateryna V., Wang, Michael, Young, Guy, Alexander, W. Allan, Al‐Sabbagh, Ahmad, Bonzo, Daniel, Macie, Christopher, Wilkinson, Thomas A., Kessler, Craig

“…Introduction Haemophilia patients with inhibitors often require a bypassing agent (BPA) for bleeding episode management. Eptacog beta (EB) is a new…”
Get full text

Reduced Plasma Levodopa Fluctuations with More Frequent Administration of a Novel Carbidopa/Levodopa Functionally Scored Tablet by Chase, Thomas N., AL‐Sabbagh, Ahmad, Koga, Minako, Clarence‐Smith, Kathleen

“…Levodopa/carbidopa remains the gold standard for treating Parkinson disease (PD), but chronic pulsatile administration contributes to motor complications. This…”
Get full text

PERSEPT 3: A phase 3 clinical trial to evaluate the haemostatic efficacy of eptacog beta (recombinant human FVIIa) in perioperative care in subjects with haemophilia A or B with inhibitors by Escobar, Miguel, Luck, James, Averianov, Yevhenii, Ducore, Jonathan, Fernández, Maria Fernanda López, Giermasz, Adam, Hart, Daniel P., Journeycake, Janna, Kessler, Craig, Leissinger, Cindy, Mahlangu, Johnny, Martinez, Laura Villarreal, Miesbach, Wolfgang, Mitha, Ismail Haroon, Quon, Doris, Reding, Mark T., Schved, Jean‐François, Stasyshyn, Oleksandra, Vilchevska, Kateryna V., Wang, Michael, Windyga, Jerzy, Alexander, W. Allan, Al‐Sabbagh, Ahmad, Bonzo, Daniel, Mitchell, Ian S., Wilkinson, Thomas A., Hermans, Cédric

“…Introduction Surgical procedures in persons with haemophilia A or B with inhibitors (PwHABI) require the use of bypassing agents (BPA) and carry a high risk of…”
Get full text

Patient attitudes and understanding about biosimilars: an international cross-sectional survey by Jacobs, Ira, Singh, Ena, Sewell, K Lea, Al-Sabbagh, Ahmad, Shane, Lesley G

“…To understand the levels of awareness, usage, and knowledge of biosimilars among patients, caregivers, and the general population in the US and the European…”
Get full text

Downregulation of Lymphoid enhancer‐binding factor 1 (LEF‐1) expression (by immunohistochemistry and/ flow cytometry) in chronic Lymphocytic Leukemia with atypical immunophenotypic and cytologic features by Soliman, Dina S., Al‐Kuwari, Einas, Siveen, Kodappully S, Al‐Abdulla, Rajaa, Chandra, Prem, Yassin, Mohamed, Nashwan, Abdulqader, Hilmi, Feryal A, Taha, Ruba Y, Nawaz, Zafar, El‐Omri, Halima, Mateo, Jericha M, Al‐Sabbagh, Ahmad

“…Introduction Lymphoid enhancer‐binding factor 1 (LEF‐1) overexpression has been recently remarkably reported in chronic lymphocytic leukemia/small lymphocytic…”
Get full text

A study of 18F-FLT positron emission tomography/computed tomography imaging in cases of prefibrotic/early primary myelofibrosis and essential thrombocythemia by Yassin, Mohamed A., Nehmeh, Sadek A., Nashwan, Abdulqadir J., Kohla, Samah A., Mohamed, Shehab F., Ismail, Omar M., Sabbagh, Ahmad Al, Ibrahim, Firyal, Soliman, Dina S., Szabados, Lajos, Fayad, Hadi

“…The objectives of this research project are to study in patients with primary myelofibrosis (PMF) and Essential Thrombocythemia (ET); (1) the uptake patterns…”
Get full text

Adjuvant Radiotherapy for Groin Node Metastases Following Surgery for Vulvar Cancer: A Systematic Review by Ferrari, Federico, Ismail, Lamiese, Sabbagh, Ahmad, Hardern, Kieran, Owens, Robert, Gozzini, Elisa, Soleymani Majd, Hooman

“…Lymph node metastasis in vulvar cancer is a critical prognostic factor associated with higher recurrence and decreased survival. A survival benefit is reported…”
Get full text

Assessing Bone Marrow Activity with [18F]FLT PET in Patients with Essential Thrombocythemia and Prefibrotic Myelofibrosis: A Proof of Concept by Yassin, Mohamed A., Nehmeh, Sadek A., Nashwan, Abdulqadir J., Kohla, Samah A., Mohamed, Shehab F., Ismail, Omar M., Al Sabbagh, Ahmad, Soliman, Dina S., Szabados, Lajos, Fayad, Hadi

“…Objectives: This study aims to assess the value of FLT-PET as a non-invasive tool to differentiate between patients with ET and Pre-PMF. This study is a pilot…”
Get full text

Characterization of circulating myeloma tumor cells by next generation flowcytometry in scleromyxedema patient: a case report by Taha, Ruba Y., Hasan, Saba, Ibrahim, Firyal, Chantran, Yannick, Sabah, Hesham El, Sivaraman, Siveen, Bozom, Issam Al, Sabbagh, Ahmad Al, Garderet, Laurent, Omri, Halima El

“…Scleromyxedema (rare cutaneous mucinosis), is characterized by the formation of lichenoid papules and presence of Serum monoclonal IgG in most cases, or all;…”
Get full text

Composite Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Mantle Cell Lymphoma; Small Cell Variant: A Real Diagnostic Challenge. Case Presentation and Review of Literature by Ibrahim, Feryal, Al Sabbagh, Ahmad, Amer, Aliaa, Soliman, Dina S, Al Sabah, Hesham

“…BACKGROUND Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma (MCL) both have a common origin arising from mature CD5+…”
Get full text

A Rare Case of Systemic Mastocytosis with Associated Hematologic Neoplasm (SM-AHN) Involving Chronic Myeloid Leukemia: A Case Report and Literature Review by Ibrahim, Feryal A, Abdulla, Mohammad A J, Soliman, Dina, Al Sabbagh, Ahmad, Nawaz, Zafar, Akiki, Susanna Jane, Shwaylia, Hawraa, Yassin, Mohamed A

“…BACKGROUND Single or multiple cell line dysplasia is a characteristic feature of myelodysplastic syndrome. However, significant dysgranulopoiesis is not a…”
Get full text

Chronic Myeloid Leukemia with cryptic Philadelphia translocation and extramedullary B-lymphoid blast phase as an initial presentation by Soliman, Dina S, Amer, Aliaa M, Mudawi, Deena, Al-Sabbagh, Zafar, Alkuwari, Einas, Al-Sabbagh, Ahmad, Ibrahim, Feryal, Yassin, Mohamed A

“…Chronic Myeloid Leukemia (CML) is a clonal myeloproliferative neoplasm (MPN) characterized by the presence of a reciprocal translocation between the long arms…”
Get full text

Rare aggressive natural killer cell leukemia presented with bone marrow fibrosis - a diagnostic challenge by Soliman, Dina S, Sabbagh, Ahmad Al, Omri, Halima El, Ibrahim, Firyal A, Amer, Aliaa M, Otazu, Ivone B

“…Aggressive natural killer cell leukemia is an extraordinary rare aggressive malignant neoplasm of natural killer cells. Although its first recognition as a…”
Get full text

A Challenging Case of Gamma Delta T-Cell Lymphoma with Precursor T-Cells and Marked Eosinophilia: A Case Report by Kohla, Samah, Ibrahim, Feryal, Bilal, Ilham, Al Kuwari, Einas, Al-Sabbagh, Ahmad

“…Gamma-delta (γδ) T-cell lymphomas are very rare and aggressive neoplasms. We describe here a challenging case of γδ T-cell neoplasm composed of γδ mature…”
Get full text

Mixed Phenotype Acute Leukemia with Two Immunophenotypically Distinct B and T Blasts Populations, Double Ph^+ Chromosome and Complex Karyotype: Report of an Unusual Case by Kohla, Samah A., Sabbagh, Ahmad Al, Omri, Halima El, Ibrahim, Firyal A., Otazu, Ivone B., Alhajri, Hessa, Yassin, Mohamed A.

“…Mixed phenotype acute leukemia (MPAL) is considered as a rare type of leukemia with an incidence of less than 4% of all acute leukemia based on the most recent…”
Get full text

P190BCR-ABL1 in a Patient with Philadelphia Chromosome Positive T-Cell Acute Lymphoblastic Leukemia: A Rare Case Report and Review of Literature by Kohla, Samah, EL Kourashy, Sarah, Nawaz, Zafar, Youssef, Reda, Al-Sabbagh, Ahmad, Ibrahim, Feryal A.

“…T-acute lymphoblastic leukemia/lymphoblastic lymphoma (T-ALL/LBL) is rare and aggressive leukemia. Philadelphia chromosome positive (Ph+) is the most common…”
Get full text

Acute Myeloid Leukemia in Qatar (2010–2016): Clinical, Biological, and Prognostic Factors and Treatment Outcomes by El Omri, Halima, Taha, Ruba Yasin, Elomri, Adel, Kacem, Nancy, Elsabah, Hesham, Ellahie, Anil Yousaf, Gamil, Amna, Ibrahim, Firyal, Soliman, Dina Sameh Abdelrahman, El Akiki, Susanna Jane Lawson, Nawaz, Zafar, Al Sabbagh, Ahmad, El Omri, Abdelfatteh

“…The current study retrospectively evaluated cytogenetic profiles, various prognostic factors, and survival outcomes in 128 acute myeloid leukemia (AML)…”
Get full text

Aberrant Acquisition of T-cell Associated Markers in Plasma Cell Neoplasms: An Aggressive Disease with Extramedullary Involvement and Very Short Survival by Soliman, Dina Sameh A, El Sabah, Hesham, Ganwo, Ibrahim, Amer, Aliaa, Taha, Ruba Y, Szabados, Lajos, Eldean, Mouhammad Sharaf, Al-Sabbagh, Ahmad, Ibrahim, Feryal

“…Plasma cell neoplasms can show aberrant expression of different lineage-related antigens; however, co-expression of T-cell-associated markers on malignant…”
Get full text