Search Results - "Sabato, Philip E"

Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID‐19 Infection by Nicol, Melanie R., Joshi, Abhay, Rizk, Matthew L., Sabato, Philip E., Savic, Radojka M., Wesche, David, Zheng, Jenny H., Cook, Jack

“…Chloroquine and hydroxychloroquine are quinoline derivatives used to treat malaria. To date, these medications are not approved for the treatment of viral…”
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Population Pharmacokinetics, Exposure-Response, and Probability of Target Attainment Analyses for Tedizolid in Adolescent Patients with Acute Bacterial Skin and Skin Structure Infections by Li, Dan, Sabato, Philip E, Guiastrennec, Benjamin, Ouerdani, Aziz, Feng, Hwa-Ping, Duval, Vincent, De Anda, Carisa S, Sears, Pamela S, Chou, Margaret Z, Hardalo, Catherine, Broyde, Natalya, Rizk, Matthew L

“…Tedizolid phosphate is an oxazolidinone antibacterial agent approved for the treatment of Gram-positive acute bacterial skin and skin structure infections…”
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Discovery of Methyl 4′-Methyl-5-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)-[1,1′-biphenyl]-3-carboxylate, an Improved Small-Molecule Inhibitor of c-Myc-Max Dimerization by Chauhan, Jay, Wang, Huabo, Yap, Jeremy L., Sabato, Philip E., Hu, Angela, Prochownik, Edward V., Fletcher, Steven

“…c‐Myc is a basic helix‐loop‐helix‐leucine zipper (bHLH‐ZIP) transcription factor that is responsible for the transcription of a wide range of target genes…”
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Disruption of Myc-Max heterodimerization with improved cell-penetrating analogs of the small molecule 10074-G5 by Wang, Huabo, Chauhan, Jay, Hu, Angela, Pendleton, Kelsey, Yap, Jeremy L, Sabato, Philip E, Jones, Jace W, Perri, Mariarita, Yu, Jianshi, Cione, Erika, Kane, Maureen A, Fletcher, Steven, Prochownik, Edward V

“…The c-Myc (Myc) oncoprotein is a high-value therapeutic target given that it is deregulated in multiple types of cancer. However, potent small molecule…”
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Erratum: Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5 by Wang, Huabo, Chauhan, Jay, Hu, Angela, Pendleton, Kelsey, Yap, Jeremy L, Sabato, Philip E, Jones, Jace W, Perri, Mariarita, Yu, Jianshi, Cione, Erika, Kane, Maureen A, Fletcher, Steven, Prochownik, Edward V

“…[This corrects the article DOI: 10.18632/oncotarget.1108.]…”
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590. Activities of Cefepime-Taniborbactam and Ceftazidime-Avibactam against Cefepime-Resistant Respiratory Gram-Negative Pathogens in a Hollow Fiber Infection Model by Avery, Lindsay M, Edwards, Mitchell, Yi, Fan, Sabato, Philip E, Moeck, Greg, Pevear, Daniel C

“…Abstract Background Cefepime-taniborbactam (FTB) combines cefepime (FEP), a fourth generation cephalosporin with taniborbactam, a novel inhibitor of metallo…”
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