Search Results - "Sabatino, Lina"

Targeting CXCR4 and CD47 Receptors: An Overview of New and Old Molecules for a Biological Personalized Anticancer Therapy by Leo, Manuela, Sabatino, Lina

“…Biological therapy, with its multifaceted applications, has revolutionized the treatment of tumors, mainly due to its ability to exclusively target cancer…”
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miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer by Barisciano, Giovannina, Colangelo, Tommaso, Rosato, Valeria, Muccillo, Livio, Taddei, Maria Letizia, Ippolito, Luigi, Chiarugi, Paola, Galgani, Mario, Bruzzaniti, Sara, Matarese, Giuseppe, Fassan, Matteo, Agostini, Marco, Bergamo, Francesca, Pucciarelli, Salvatore, Carbone, Annalucia, Mazzoccoli, Gianluigi, Colantuoni, Vittorio, Bianchi, Fabrizio, Sabatino, Lina

“…Background Metabolic reprogramming towards aerobic glycolysis in cancer supports unrestricted cell proliferation, survival and chemoresistance. The molecular…”
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MicroRNA-130b Promotes Tumor Development and Is Associated with Poor Prognosis in Colorectal Cancer by Colangelo, Tommaso, Fucci, Alessandra, Votino, Carolina, Sabatino, Lina, Pancione, Massimo, Laudanna, Carmelo, Binaschi, Monica, Bigioni, Mario, Alberto Maggi, Carlo, Parente, Domenico, Forte, Nicola, Colantuoni, Vittorio

“…Abstract MicroRNA-130b (miR-130b) is involved in several biologic processes; its role in colorectal tumorigenesis has not been addressed so far. Herein, we…”
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Chiral phenoxyacetic acid analogues inhibit colon cancer cell proliferation acting as PPARγ partial agonists by Sabatino, Lina, Ziccardi, Pamela, Cerchia, Carmen, Muccillo, Livio, Piemontese, Luca, Loiodice, Fulvio, Colantuoni, Vittorio, Lupo, Angelo, Lavecchia, Antonio

“…Peroxisome Proliferator-Activated Receptor γ (PPARγ) is an important sensor at the crossroad of diabetes, obesity, immunity and cancer as it regulates…”
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Immune Escape Mechanisms in Colorectal Cancer Pathogenesis and Liver Metastasis by Colantuoni, Vittorio, Manfrin, Erminia, Sabatino, Lina, Febbraro, Antonio, Remo, Andrea, Giordano, Guido, Pancione, Massimo, Ceccarelli, Michele

“…Over the past decade, growing evidence indicates that the tumor microenvironment (TME) contributes with genomic/epigenomic aberrations of malignant cells to…”
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Molecular and environmental analysis of Campania (Italy) sweet cherry (Prunus avium L.) cultivars for biocultural refugia identification and conservation by Muccillo, Livio, Colantuoni, Vittorio, Sciarrillo, Rosaria, Baiamonte, Giuseppe, Salerno, Giovanni, Marziano, Mario, Sabatino, Lina, Guarino, Carmine

“…Conservation of agrobiodiversity is a major concern worldwide. Several strategies have been designed and programmed to reduce biodiversity erosion due to…”
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emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer by Sabatino, Lina, Pancione, Massimo, Votino, Carolina, Colangelo, Tommaso, Lupo, Angelo, Novellino, Ettore, Lavecchia, Antonio, Colantuoni, Vittorio

“…Multiple lines of evidence indicate that Wnt/β-catenin signaling plays a fundamental role in colorectal cancer(CRC)initiation and progression.Recent…”
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Combined SERS-Raman screening of HER2-overexpressing or silenced breast cancer cell lines by Spaziani, Sara, Esposito, Alessandro, Barisciano, Giovannina, Quero, Giuseppe, Elumalai, Satheeshkumar, Leo, Manuela, Colantuoni, Vittorio, Mangini, Maria, Pisco, Marco, Sabatino, Lina, De Luca, Anna Chiara, Cusano, Andrea

“…Breast cancer (BC) is a heterogeneous neoplasm characterized by several subtypes. One of the most aggressive with high metastasis rates presents overexpression…”
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The Pomace Extract Taurisolo Protects Rat Brain From Ischemia-Reperfusion Injury by Lapi, Dominga, Stornaiuolo, Mariano, Sabatino, Lina, Sommella, Eduardo, Tenore, Giancarlo, Daglia, Maria, Scuri, Rossana, Di Maro, Martina, Colantuoni, Antonio, Novellino, Ettore

“…Taurisolo is a pomace extract from Aglianico Grapes, a wine cultivar native to Campania (Southern Italy). It exhibits a very high polyphenolic content and,…”
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Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells by Leo, Manuela, Muccillo, Livio, Dugo, Laura, Bernini, Roberta, Santi, Luca, Sabatino, Lina

“…Olive oil production is associated with the generation of oil production waste products (OPWPs) rich in water-soluble polyphenols that represent serious…”
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CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma by Mezzapelle, Rosanna, De Marchis, Francesco, Passera, Chiara, Leo, Manuela, Brambilla, Francesca, Colombo, Federica, Casalgrandi, Maura, Preti, Alessandro, Zambrano, Samuel, Castellani, Patrizia, Ertassi, Riccardo, Silingardi, Marco, Caprioglio, Francesca, Basso, Veronica, Boldorini, Renzo, Carretta, Angelo, Sanvito, Francesca, Rena, Ottavio, Rubartelli, Anna, Sabatino, Lina, Mondino, Anna, Crippa, Massimo P, Colantuoni, Vittorio, Bianchi, Marco E

“…Boosting antitumor immunity has emerged as a powerful strategy in cancer treatment. While releasing T‐cell brakes has received most attention, tumor…”
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Geometric Features of the Pial Arteriolar Networks in Spontaneous Hypertensive Rats: A Crucial Aspect Underlying the Blood Flow Regulation by Lapi, Dominga, Di Maro, Martina, Serao, Nicola, Chiurazzi, Martina, Varanini, Maurizio, Sabatino, Lina, Scuri, Rossana, Colantuoni, Antonio, Guida, Bruna

“…Background Several studies indicate that hypertension causes major changes in the structure of the vessel wall by affecting the regulation of blood supply to…”
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Quercetin’s Dual Mode of Action to Counteract the Sp1-miR-27a Axis in Colorectal Cancer Cells by Fosso, Emanuele, Leo, Manuela, Muccillo, Livio, Mandrone, Vittorio Maria, Di Meo, Maria Chiara, Molinario, Annamaria, Varricchio, Ettore, Sabatino, Lina

“…Quercetin (Qc) inhibits cell proliferation and induces apoptosis in a variety of cancer cells. The molecular mechanism of action has not been fully elucidated;…”
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Correction: miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer by Barisciano, Giovannina, Colangelo, Tommaso, Rosato, Valeria, Muccillo, Livio, Taddei, Maria Letizia, Ippolito, Luigi, Chiarugi, Paola, Galgani, Mario, Bruzzaniti, Sara, Matarese, Giuseppe, Fassan, Matteo, Agostini, Marco, Bergamo, Francesca, Pucciarelli, Salvatore, Carbone, Annalucia, Mazzoccoli, Gianluigi, Colantuoni, Vittorio, Bianchi, Fabrizio, Sabatino, Lina

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Raman and Surface Enhanced Raman spectroscopy analysis of breast cancer cell lines with different HER2 expression profiles by Spaziani, Sara, Esposito, Alessandro, Barisciano, Giovannina, Quero, Giuseppe, Leo, Manuela, Colantuoni, Vittorio, Mangini, Maria, Pisco, Marco, Sabatino, Lina, De Luca, Anna Chiara, Cusano, Andrea

“…Assessing HER2 expression in breast cancer cells holds significant diagnostic and prognostic importance. Traditional methods like immunohistochemistry and in…”
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Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome by Pancione, Massimo, Sabatino, Lina, Fucci, Alessandra, Carafa, Vincenzo, Nebbioso, Angela, Forte, Nicola, Febbraro, Antonio, Parente, Domenico, Ambrosino, Concetta, Normanno, Nicola, Altucci, Lucia, Colantuoni, Vittorio

“…The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is…”
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Ensemble of gene signatures identifies novel biomarkers in colorectal cancer activated through PPARγ and TNFα signaling by Pagnotta, Stefano Maria, Laudanna, Carmelo, Pancione, Massimo, Sabatino, Lina, Votino, Carolina, Remo, Andrea, Cerulo, Luigi, Zoppoli, Pietro, Manfrin, Erminia, Colantuoni, Vittorio, Ceccarelli, Michele

“…We describe a novel bioinformatic and translational pathology approach, gene Signature Finder Algorithm (gSFA) to identify biomarkers associated with…”
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Transcriptomic Analysis of Colorectal Cancer Cells Treated with Oil Production Waste Products (OPWPs) Reveals Enrichment of Pathways of Mitochondrial Functionality by Leo, Manuela, Muccillo, Livio, Pranzini, Erica, Barisciano, Giovannina, Parri, Matteo, Lopatriello, Giulia, Carlomagno, Marco, Santi, Alice, Taddei, Maria Letizia, Sabatino, Lina

“…Oil production waste products (OPWPs) derive from olive mill and represent a crucial environmental problem due to their high polyphenolic content able to…”
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Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues by Simmer, Femke, Brinkman, Arie B., Assenov, Yassen, Matarese, Filomena, Kaan, Anita, Sabatino, Lina, Villanueva, Alberto, Huertas, Dori, Esteller, Manel, Lengauer, Thomas, Bock, Christoph, Colantuoni, Vittorio, Altucci, Lucia, Stunnenberg, Hendrik G.

“…Aberrant DNA methylation often occurs in colorectal cancer (CRC). In our study we applied a genome-wide DNA methylation analysis approach, MethylCap-seq, to…”
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Proteomic characterization of peroxisome proliferator-activated receptor-γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype by Milone, Maria Rita, Pucci, Biagio, Colangelo, Tommaso, Lombardi, Rita, Iannelli, Federica, Colantuoni, Vittorio, Sabatino, Lina, Budillon, Alfredo

“…Peroxisome proliferator-activated receptor-γ (PPARγ) is a transcription factor of the nuclear hormone receptor superfamily implicated in a wide range of…”
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