Search Results - "Sabantsev, Anton"

Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling by Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian

“…ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes,…”
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The voyage is as important as the harbor by Sabantsev, Anton, Deindl, Sebastian

“…To find nucleosomes, chromatin remodelers slide and hop along DNA, and their direction of approach affects the direction that nucleosomes slide in…”
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The Chd1 chromatin remodeler shifts hexasomes unidirectionally by Levendosky, Robert F, Sabantsev, Anton, Deindl, Sebastian, Bowman, Gregory D

“…Despite their canonical two-fold symmetry, nucleosomes in biological contexts are often asymmetric: functionalized with post-translational modifications…”
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Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome by Bacic, Luka, Gaullier, Guillaume, Sabantsev, Anton, Lehmann, Laura C, Brackmann, Klaus, Dimakou, Despoina, Halic, Mario, Hewitt, Graeme, Boulton, Simon J, Deindl, Sebastian

“…The chromatin remodeler ALC1 is recruited to and activated by DNA damage-induced poly(ADP-ribose) (PAR) chains deposited by PARP1/PARP2/HPF1 upon detection of…”
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Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1 by Bacic, Luka, Gaullier, Guillaume, Mohapatra, Jugal, Mao, Guanzhong, Brackmann, Klaus, Panfilov, Mikhail, Liszczak, Glen, Sabantsev, Anton, Deindl, Sebastian

“…The chromatin remodeler ALC1 is activated by DNA damage-induced poly(ADP-ribose) deposited by PARP1/PARP2 and their co-factor HPF1. ALC1 has emerged as a…”
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DNA surface exploration and operator bypassing during target search by Marklund, Emil, van Oosten, Brad, Mao, Guanzhong, Amselem, Elias, Kipper, Kalle, Sabantsev, Anton, Emmerich, Andrew, Globisch, Daniel, Zheng, Xuan, Lehmann, Laura C., Berg, Otto G., Johansson, Magnus, Elf, Johan, Deindl, Sebastian

“…Many proteins that bind specific DNA sequences search the genome by combining three-dimensional diffusion with one-dimensional sliding on nonspecific DNA 1 – 5…”
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Detection of spacer precursors formed in vivo during primed CRISPR adaptation by Shiriaeva, Anna A., Savitskaya, Ekaterina, Datsenko, Kirill A., Vvedenskaya, Irina O., Fedorova, Iana, Morozova, Natalia, Metlitskaya, Anastasia, Sabantsev, Anton, Nickels, Bryce E., Severinov, Konstantin, Semenova, Ekaterina

“…Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity against foreign DNA. Immunity involves adaptation, the integration of…”
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Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system by Morozova, Natalia, Sabantsev, Anton, Bogdanova, Ekaterina, Fedorova, Yana, Maikova, Anna, Vedyaykin, Alexey, Rodic, Andjela, Djordjevic, Marko, Khodorkovskii, Mikhail, Severinov, Konstantin

“…Type II restriction-modification (R-M) systems encode a restriction endonuclease that cleaves DNA at specific sites, and a methyltransferase that modifies same…”
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Extracellular membrane vesicles secreted by mycoplasma Acholeplasma laidlawii PG8 are enriched in virulence proteins by Chernov, Vladislav M., Mouzykantov, Alexey A., Baranova, Natalia B., Medvedeva, Elena S., Grygorieva, Tatiana Yu, Trushin, Maxim V., Vishnyakov, Innokentii E., Sabantsev, Anton V., Borchsenius, Sergei N., Chernova, Olga A.

“…Mycoplasmas (class Mollicutes), the smallest prokaryotes capable of self-replication, as well as Archaea, Gram-positive and Gram-negative bacteria…”
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New insights into FtsZ rearrangements during the cell division of Escherichia coli from single‐molecule localization microscopy of fixed cells by Vedyaykin, Alexey D., Vishnyakov, Innokentii E., Polinovskaya, Vasilisa S., Khodorkovskii, Mikhail A., Sabantsev, Anton V.

“…FtsZ – a prokaryotic tubulin homolog – is one of the central components of bacterial division machinery. At the early stage of cytokinesis FtsZ forms the…”
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Gelsolin-like Activation of Villin: Calcium Sensitivity of the Long Helix in Domain 6 by Fedechkin, Stanislav O, Brockerman, Jacob, Pfaff, Danielle A, Burns, Lucian, Webb, Terry, Nelson, Alexander, Zhang, Fengli, Sabantsev, Anton V, Melnikov, Alexey S, McKnight, C. James, Smirnov, Serge L

“…Villin is a gelsolin-like cytoskeleton regulator localized in the brush border at the apical end of epithelial cells. Villin regulates microvilli by bundling…”
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Recombinant FtsZ Proteins from Mollicutes Interact with Escherichia coli Division Machinery by Vedyaykin, Alexey D., Sabantsev, Anton V., Khodorkovskii, Mikhail A., Kayumov, Airat R., Vishnyakov, Innokentii E.

“…FtsZ is a well-known prokaryotic tubulin homologue. It participates in cytokinesis in most bacteria and is considered to be a key division protein. However,…”
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New insights into FtsZ rearrangements during the cell division of E scherichia coli from single‐molecule localization microscopy of fixed cells by Vedyaykin, Alexey D, Vishnyakov, Innokentii E, Polinovskaya, Vasilisa S, Khodorkovskii, Mikhail A, Sabantsev, Anton V

“…Abstract FtsZ – a prokaryotic tubulin homolog – is one of the central components of bacterial division machinery. At the early stage of cytokinesis FtsZ forms…”
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Recent advances in single-molecule fluorescence microscopy render structural biology dynamic by Bacic, Luka, Sabantsev, Anton, Deindl, Sebastian

“…•Single-molecule fluorescence microscopy is a powerful tool to study the structural dynamics of biological macromolecules.•Recent developments in…”
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Spatiotemporally controlled generation of NTPs for single-molecule studies by Sabantsev, Anton, Mao, Guanzhong, Aguirre Rivera, Javier, Panfilov, Mikhail, Arseniev, Anatolii, Ho, Oanh, Khodorkovskiy, Mikhail, Deindl, Sebastian

“…Many essential processes in the cell depend on proteins that use nucleoside triphosphates (NTPs). Methods that directly monitor the often-complex dynamics of…”
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Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch by Lehmann, Laura C., Bacic, Luka, Hewitt, Graeme, Brackmann, Klaus, Sabantsev, Anton, Gaullier, Guillaume, Pytharopoulou, Sofia, Degliesposti, Gianluca, Okkenhaug, Hanneke, Tan, Song, Costa, Alessandro, Skehel, J. Mark, Boulton, Simon J., Deindl, Sebastian

“…Upon DNA damage, the ALC1/CHD1L nucleosome remodeling enzyme (remodeler) is activated by binding to poly(ADP-ribose). How activated ALC1 recognizes the…”
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Deinococcus radiodurans RecA nucleoprotein filaments characterized at the single-molecule level with optical tweezers by Pobegalov, Georgii, Cherevatenko, Galina, Alekseev, Aleksandr, Sabantsev, Anton, Kovaleva, Oksana, Vedyaykin, Alexey, Morozova, Natalia, Baitin, Dmitrii, Khodorkovskii, Mikhail

“…Deinococcus radiodurans can survive extreme doses of ionizing radiation due to the very efficient DNA repair mechanisms that are able to cope even with…”
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Real-Time RecA Filament Disassembly in the Presence of RecX Monitored using Single-Molecule Manipulation by Optical Tweezers by Pobegalov, Georgii, Alekseev, Alexandr, Sabantsev, Anton, Melnikov, Alexey, Khodorkovskiy, Mikhail, Baitin, Dmitry

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