Search Results - "Sabando, Ainara Ruiz de"
-
1
Deep learning-based approach to the characterization and quantification of histopathology in mouse models of colitis
Published in PloS one (29-08-2022)“…Inflammatory bowel disease (IBD) is a chronic immune-mediated disease of the gastrointestinal tract. While therapies exist, response can be limited within the…”
Get full text
Journal Article -
2
Ganglion Cell Layer Thinning in Alzheimer's Disease
Published in Medicina (Kaunas, Lithuania) (21-10-2020)“…The main advantages of optical retinal imaging may allow researchers to achieve deeper analysis of retinal ganglion cells (GC) in vivo using optical coherence…”
Get full text
Journal Article -
3
KLF5 protects the intestinal epithelium against Th17 immune response in a murine colitis model
Published in JCI insight (08-04-2022)“…Inflammatory bowel disease (IBD) is a chronic illness characterized by dysregulated immune cascades in the intestines, in which the Th17 immune response plays…”
Get full text
Journal Article -
4
A01 Somatic mosaicism of the HTT cag repeat in intermediate allele carriers with neurocognitive symptoms compatible with huntington disease
Published in Journal of neurology, neurosurgery and psychiatry (12-09-2022)“…We aimed to determine the possible role of CAG somatic expansions on the clinical expression of intermediate allele (IA) carriers of the HTT gene, responsible…”
Get full text
Journal Article -
5
Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype
Published in European journal of human genetics : EJHG (01-07-2024)“…Huntington disease (HD) is a neurodegenerative disorder caused by ≥36 CAGs in the HTT gene. Intermediate alleles (IAs) (27-35 CAGs) are not considered…”
Get full text
Journal Article -
6
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation
Published in Scientific reports (18-01-2017)“…Post-translational modification by ubiquitin and ubiquitin-like proteins (UbLs) is fundamental for maintaining protein homeostasis. Efficient isolation of UbL…”
Get full text
Journal Article -
7
Deep learning-based approach to the characterization and quantification of histopathology in mouse models of colitis
Published in PloS one (29-08-2022)“…Inflammatory bowel disease (IBD) is a chronic immune-mediated disease of the gastrointestinal tract. While therapies exist, response can be limited within the…”
Get full text
Journal Article -
8
ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer
Published in Molecular cancer therapeutics (01-01-2016)“…Colorectal cancer is one of the leading causes of cancer mortality in Western civilization. Studies have shown that colorectal cancer arises as a consequence…”
Get full text
Journal Article -
9
Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)
Published in BMC cancer (27-11-2019)“…Genetic testing for BRCA1/2 genes is widely used as a strategy to reduce incidence and morbidity of hereditary breast and ovarian cancer (HBOC). The purpose of…”
Get full text
Journal Article -
10
Validation of diagnostic codes and epidemiologic trends of Huntington disease: a population-based study in Navarre, Spain
Published in Orphanet journal of rare diseases (10-02-2021)“…There is great heterogeneity on geographic and temporary Huntington disease (HD) epidemiological estimates. Most research studies of rare diseases, including…”
Get full text
Journal Article -
11
Correction to: Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)
Published in BMC cancer (17-12-2019)“…Following publication of the original article [1], the authors reported an error in Figure 2, where the color code of the text boxes is reversed. Figure…”
Get full text
Journal Article -
12
Mo1644: A DEEP LEARNING-BASED APPROACH TO IDENTIFY PATHOLOGIES IN MOUSE MODELS OF COLITIS
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
Journal Article -
13
-
14
-
15
Fr619 DEEP LEARNING CLASSIFIER TO DETECT INFLAMED AND NON-INFLAMED AREAS WITHIN WHOLE MOUSE COLONS
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2021)Get full text
Journal Article -
16
-
17
1016 - Mice with Intestine-Specific Deletion of KRÜPPEL-Like Factor 5 Exhibit an Inflammatory Phenotype
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2018)Get full text
Journal Article -
18
-
19
-
20
Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease
Published in Human molecular genetics (06-03-2023)“…Abstract We aimed to determine the genetic diversity and molecular characteristics of the Huntington disease (HD) gene (HTT) in Spain. We performed an extended…”
Get full text
Journal Article