Search Results - "Saavedra, H."

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition by Vande Walle, Lieselotte, Stowe, Irma B, Šácha, Pavel, Lee, Bettina L, Demon, Dieter, Fossoul, Amelie, Van Hauwermeiren, Filip, Saavedra, Pedro H V, Šimon, Petr, Šubrt, Vladimír, Kostka, Libor, Stivala, Craig E, Pham, Victoria C, Staben, Steven T, Yamazoe, Sayumi, Konvalinka, Jan, Kayagaki, Nobuhiko, Lamkanfi, Mohamed

“…The nucleotide-binding-domain (NBD)-and leucine-rich repeat (LRR)-containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome drives pathological…”
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Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis by Saavedra, Pedro H. V., Huang, Linyan, Ghazavi, Farzaneh, Kourula, Stephanie, Vanden Berghe, Tom, Takahashi, Nozomi, Vandenabeele, Peter, Lamkanfi, Mohamed

“…Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this…”
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Neurocysticercosis. A frequent cause of seizures, epilepsy, and other neurological morbidity in most of the world by Bustos, J., Gonzales, I., Saavedra, H., Handali, S., Garcia, H.H.

“…Neurocysticercosis is endemic in most of the world and in endemic areas it accounts for approximately 30% of cases of epilepsy. Appropriate diagnosis and…”
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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation by Van Gorp, Hanne, Saavedra, Pedro H. V., de Vasconcelos, Nathalia M., Van Opdenbosch, Nina, Vande Walle, Lieselotte, Matusiak, Magdalena, Prencipe, Giusi, Insalaco, Antonella, Van Hauwermeiren, Filip, Demon, Dieter, Bogaert, Delfien J., Dullaers, Melissa, De Baere, Elfride, Hochepied, Tino, Dehoorne, Joke, Vermaelen, Karim Y., Haerynck, Filomeen, De Benedetti, Fabrizio, Lamkanfi, Mohamed

“…Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease worldwide. It is caused by mutations in the inflammasome adaptor…”
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Multiantigen print immunoassay (MAPIA) for the diagnosis of neurocysticercosis: a single-center diagnostic optimization and accuracy study in Lima, Peru by Toribio, L, Guzman, C, Noazin, S, Zimic-Sheen, A, Zimic, M, Gonzales, I, Saavedra, H, Pretell, E J, Bustos, J A, Handali, S, García, H H

“…Neurocysticercosis (NCC) is the most common helminthic infection of the human central nervous system. The antibody detection assay of choice is the…”
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GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever by Kanneganti, Apurva, Malireddi, R K Subbarao, Saavedra, Pedro H V, Vande Walle, Lieselotte, Van Gorp, Hanne, Kambara, Hiroto, Tillman, Heather, Vogel, Peter, Luo, Hongbo R, Xavier, Ramnik J, Chi, Hongbo, Lamkanfi, Mohamed

“…Pyroptosis is an inflammasome-induced lytic cell death mode, the physiological role of which in chronic inflammatory diseases is unknown. Familial…”
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The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1 Cdk4 and Nek2 by Zeng, X, Shaikh, F Y, Harrison, M K, Adon, A M, Trimboli, A J, Carroll, K A, Sharma, N, Timmers, C, Chodosh, L A, Leone, G, Saavedra, H I

“…Centrosome amplification (CA) contributes to carcinogenesis by generating aneuploidy. Elevated frequencies of CA in most benign breast lesions and primary…”
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Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice by Dufies, Océane, Doye, Anne, Courjon, Johan, Torre, Cédric, Michel, Gregory, Loubatier, Celine, Jacquel, Arnaud, Chaintreuil, Paul, Majoor, Alissa, Guinamard, Rodolphe R., Gallerand, Alexandre, Saavedra, Pedro H. V., Verhoeyen, Els, Rey, Amaury, Marchetti, Sandrine, Ruimy, Raymond, Czerucka, Dorota, Lamkanfi, Mohamed, Py, Bénédicte F., Munro, Patrick, Visvikis, Orane, Boyer, Laurent

“…Inflammasomes are signalling platforms that are assembled in response to infection or sterile inflammation by cytosolic pattern recognition receptors. The…”
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Immunology: Gut sensor halts viral attack by Saavedra, Pedro H V, Lamkanfi, Mohamed

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Species Surface Distribution and Surface Tension of Aqueous Solutions of MIBC and NaCl Using Molecular Dynamics Simulations by Alvarado, Omar, Quezada, Gonzalo R, Saavedra, Jorge H, Rozas, Roberto E, Toledo, Pedro G

“…Methyl isobutyl carbinol (MIBC) is a high-performance surfactant with unusual interfacial properties much appreciated in industrial applications, particularly…”
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Immunometabolism of Tissue-Resident Macrophages – An Appraisal of the Current Knowledge and Cutting-Edge Methods and Technologies by Zago, Giulia, Saavedra, Pedro H. V., Keshari, Kayvan R., Perry, Justin S. A.

“…Tissue-resident macrophages exist in unique environments, or niches, that inform their identity and function. There is an emerging body of literature…”
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Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion by Coelho, Carolina, Cordero, Radames J. B., Nosanchuk, Joshua D., Nakayasu, Ernesto S., May, Robin C., Tavares, Aldo Henrique, Bocca, Anamelia Lorenzetti, Heyman, Heino M., Castro, Raffael Araújo de, Veloso Janior, Paulo Henrique de Holanda, de Oliveira, Stephan Alberto Machado, Albuquerque, Patrícia, Saavedra, Pedro H. V., Marina, Clara Luna, Bürgel, Pedro Henrique, Casadevall, Arturo

“…Cryptococcus neoformans is an encapsulated yeast that causes disease mainly in immunosuppressed hosts. It is considered a facultative intracellular pathogen…”
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A Molecular Dynamics Simulation of Polymers’ Interactions with Kaolinite (010) Surfaces in Saline Solutions by Quezada, Gonzalo R., Leiva, Williams, Saavedra, Jorge H., Robles, Pedro, Gálvez, Edelmira, Jeldres, Ricardo I.

“…The search for polymers that meet the demands of the water recovery process in mining is a contingent challenge. Both the presence of clays and saline waters…”
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Cognition, structural brain changes and complicated grief. A population-based study by Saavedra Pérez, H C, Ikram, M A, Direk, N, Prigerson, H G, Freak-Poli, R, Verhaaren, B F J, Hofman, A, Vernooij, M, Tiemeier, H

“…Several psychosocial risk factors for complicated grief have been described. However, the association of complicated grief with cognitive and biological risk…”
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Protective and detrimental roles of inflammasomes in disease by Saavedra, Pedro H. V., Demon, Dieter, Van Gorp, Hanne, Lamkanfi, Mohamed

“…Over recent years, inflammasomes have emerged as key regulators of immune and inflammatory responses. They induce programmed cell death and direct the release…”
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Photosensitized Generation of Singlet Oxygen from Re(I) Complexes: A Photophysical Study Using LIOAS and Luminescence Techniques by Ragone, Fabricio, Saavedra, Héctor H. Martinez, Gara, Pedro M. David, Ruiz, Gustavo T., Wolcan, Ezequiel

“…Quantum yields and efficiencies of 1O2 (1Δg) production along with photophysical properties for a number of Re(I) complexes in acetonitrile solutions are…”
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Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition by Walle, Lieselotte Vande, Stowe, Irma B, Šácha, Pavel, Lee, Bettina L, Demon, Dieter, Fossoul, Amelie, Van Hauwermeiren, Filip, Saavedra, Pedro H V, Šimon, Petr, Šubr, Vladimír, Kostka, Libor, Stivala, Craig E, Pham, Victoria C, Staben, Steven T, Yamazoe, Sayumi, Konvalinka, Jan, Kayagaki, Nobuhiko, Lamkanfi, Mohamed

“…[This corrects the article DOI: 10.1371/journal.pbio.3000354.]…”
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Alkali Halide and MIBC Interaction at Typical Flotation Interfaces in Saline Water as Determined by Molecular Dynamics Simulations by Omar Alvarado, Gonzalo R. Quezada, Jorge H. Saavedra, Roberto E. Rozas, Leopoldo Gutiérrez, Pedro G. Toledo

“…The molecular structure of the liquid–vapor interfaces of aqueous solutions of alkali metal halides and methyl isobutyl carbinol (MIBC, (CH3)2CHCH2COCH3) is…”
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Clinical and Parasitological Features of Patients with American Cutaneous Leishmaniasis that Did Not Respond to Treatment with Meglumine Antimoniate by Perez-Franco, Jairo E, Cruz-Barrera, Mónica L, Robayo, Marta L, Lopez, Myriam C, Daza, Carlos D, Bedoya, Angela, Mariño, Maria L, Saavedra, Carlos H, Echeverry, Maria C

“…American cutaneous leishmaniasis (ACL) is a complicated disease producing about 67.000 new cases per year. The severity of the disease depends on the parasite…”
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Association studies to transporting proteins of fac-ReI(CO)3(pterin)(H2O) complex by Ragone, Fabricio, Saavedra, Héctor H. Martínez, García, Pablo F., Wolcan, Ezequiel, Argüello, Gerardo A., Ruiz, Gustavo T

“…A new synthetic route to acquire the water soluble complex fac -Re I (CO) 3 (pterin)(H 2 O) was carried out in aqueous solution. The complex has been obtained…”
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