Search Results - "Saavedra, Ezequiel"

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    Gene expression studies using a miniaturized thermal cycler system on board the International Space Station by Montague, Tessa G, Almansoori, Alia, Gleason, Emily J, Copeland, D Scott, Foley, Kevin, Kraves, Sebastian, Alvarez Saavedra, Ezequiel

    Published in PloS one (31-10-2018)
    “…The distance and duration of human spaceflight missions is set to markedly increase over the coming decade as we prepare to send astronauts to Mars. However,…”
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    Journal Article
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    A CRISPR-based assay for the study of eukaryotic DNA repair onboard the International Space Station by Stahl-Rommel, Sarah, Li, David, Sung, Michelle, Li, Rebecca, Vijayakumar, Aarthi, Atabay, Kutay Deniz, Bushkin, G. Guy, Castro, Christian L, Foley, Kevin D, Copeland, D. Scott, Castro-Wallace, Sarah L, Alvarez Saavedra, Ezequiel, Gleason, Emily J, Kraves, Sebastian

    Published in PloS one (30-06-2021)
    “…As we explore beyond Earth, astronauts may be at risk for harmful DNA damage caused by ionizing radiation. Double-strand breaks are a type of DNA damage that…”
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    Journal Article
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    Successful amplification of DNA aboard the International Space Station by Boguraev, Anna-Sophia, Christensen, Holly C., Bonneau, Ashley R., Pezza, John A., Nichols, Nicole M., Giraldez, Antonio J., Gray, Michelle M., Wagner, Brandon M., Aken, Jordan T., Foley, Kevin D., Copeland, D. Scott, Kraves, Sebastian, Alvarez Saavedra, Ezequiel

    Published in NPJ microgravity (16-11-2017)
    “…As the range and duration of human ventures into space increase, it becomes imperative that we understand the effects of the cosmic environment on astronaut…”
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    Journal Article
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    A fluorescence viewer for rapid molecular assay readout in space and low-resource terrestrial environments by Misquitta, Kristoff, Miller, Bess M, Malecek, Kathryn, Gleason, Emily, Martin, Kathryn, Walesky, Chad M, Foley, Kevin, Copeland, D Scott, Saavedra, Ezequiel Alvarez, Kraves, Sebastian

    Published in PloS one (2024)
    “…Fluorescence-based assays provide sensitive and adaptable methods for point of care testing, environmental monitoring, studies of protein abundance and…”
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    MicroRNA Expression in Zebrafish Embryonic Development by Wienholds, Erno, Kloosterman, Wigard P, Miska, Eric, Alvarez-Saavedra, Ezequiel, Berezikov, Eugene, de Bruijn, Ewart, Horvitz, H. Robert, Kauppinen, Sakari, Plasterk, Ronald H. A

    “…MicroRNAs (miRNAs) are small noncoding RNAs, about 21 nucleotides in length, that can regulate gene expression by base-pairing to partially complementary…”
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    Most Caenorhabditis elegans microRNAs are individually not essential for development or viability by Miska, Eric A, Alvarez-Saavedra, Ezequiel, Abbott, Allison L, Lau, Nelson C, Hellman, Andrew B, McGonagle, Shannon M, Bartel, David P, Ambros, Victor R, Horvitz, H Robert

    Published in PLoS genetics (01-12-2007)
    “…MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We…”
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    Members of the miRNA-200 Family Regulate Olfactory Neurogenesis by Choi, Philip S., Zakhary, Lisa, Choi, Wen-Yee, Caron, Sophie, Alvarez-Saavedra, Ezequiel, Miska, Eric A., McManus, Mike, Harfe, Brian, Giraldez, Antonio J., Horvitz, Robert H., Schier, Alexander F., Dulac, Catherine

    Published in Neuron (Cambridge, Mass.) (10-01-2008)
    “…MicroRNAs (miRNAs) are highly expressed in vertebrate neural tissues, but the contribution of specific miRNAs to the development and function of different…”
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    Journal Article
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    The let-7 MicroRNA Family Members mir-48, mir-84, and mir-241 Function Together to Regulate Developmental Timing in Caenorhabditis elegans by Abbott, Allison L., Alvarez-Saavedra, Ezequiel, Miska, Eric A., Lau, Nelson C., Bartel, David P., Horvitz, H. Robert, Ambros, Victor

    Published in Developmental cell (01-09-2005)
    “…The microRNA let-7 is a critical regulator of developmental timing events at the larval-to-adult transition in C. elegans. Recently, microRNAs with sequence…”
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    Journal Article
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    Microarray analysis of microRNA expression in the developing mammalian brain by Miska, Eric A, Alvarez-Saavedra, Ezequiel, Townsend, Matthew, Yoshii, Akira, Sestan, Nenad, Rakic, Pasko, Constantine-Paton, Martha, Horvitz, H Robert

    Published in Genome biology (01-01-2004)
    “…MicroRNAs are a large new class of tiny regulatory RNAs found in nematodes, plants, insects and mammals. MicroRNAs are thought to act as post-transcriptional…”
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    Journal Article
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    Many Families of C. elegans MicroRNAs Are Not Essential for Development or Viability by Alvarez-Saavedra, Ezequiel, Horvitz, H. Robert

    Published in Current biology (23-02-2010)
    “…MicroRNAs (miRNAs) are approximately 23 nt regulatory RNAs that posttranscriptionally inhibit the functions of protein-coding mRNAs. We previously found that…”
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    Journal Article
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    Implementing Hands-On Molecular and Synthetic Biology Education Using Cell-Free Technology by Huang, Ally, Bryan, Bruce, Kraves, Sebastian, Alvarez-Saavedra, Ezequiel, Stark, Jessica C

    “…Active, hands-on learning has been shown to improve educational outcomes in STEM subjects. However, implementation of hands-on activities for teaching biology…”
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    Journal Article
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    Caenorhabditis elegans and friends in Los Angeles by Alvarez-Saavedra, Ezequiel A, Miska, Eric A

    Published in Genome biology (2005)
    “…A report on the 15th Biennial International C. elegans Conference, Los Angeles, USA, 25-29 June 2005…”
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    Journal Article Conference Proceeding
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    MicroRNA expression profiles classify human cancers by Golub, Todd R, Lu, Jun, Getz, Gad, Miska, Eric A, Alvarez-Saavedra, Ezequiel, Lamb, Justin, Peck, David, Sweet-Cordero, Alejandro, Ebert, Benjamin L, Mak, Raymond H, Ferrando, Adolfo A, Downing, James R, Jacks, Tyler, Horvitz, H. Robert

    Published in Nature (09-06-2005)
    “…Recent work has revealed the existence of a class of small non-coding RNA species, known as microRNAs (miRNAs), which have critical functions across various…”
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    Validation of Cell-Free Protein Synthesis Aboard the International Space Station by Kocalar, Selin, Miller, Bess M., Huang, Ally, Gleason, Emily, Martin, Kathryn, Foley, Kevin, Copeland, D. Scott, Jewett, Michael C., Saavedra, Ezequiel Alvarez, Kraves, Sebastian

    Published in ACS synthetic biology (15-03-2024)
    “…Cell-free protein synthesis (CFPS) is a rapidly maturing in vitro gene expression platform that can be used to transcribe and translate nucleic acids at the…”
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    Many families of Caenorhabditis elegans microRNAs are not essential for development or viability by Alvarez-Saavedra, Ezequiel, Horvitz, H. Robert

    Published in Current biology (21-01-2010)
    “…MicroRNAs (miRNAs) are approximately 23 nt regulatory RNAs that posttranscriptionally inhibit the functions of protein-coding mRNAs. We previously found that…”
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    Journal Article
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