Search Results - "Saadeddin, Anas"

Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1- and TCF-dependent Mechanisms by Ibrahim, Elsayed E., Babaei-Jadidi, Roya, Saadeddin, Anas, Spencer-Dene, Bradley, Hossaini, Sina, Abuzinadah, Mohammed, Li, Ningning, Fadhil, Wakkas, Ilyas, Mohammad, Bonnet, Dominique, Nateri, Abdolrahman S.

“…Embryonic NANOG (NANOG1) is considered as an important regulator of pluripotency while NANOGP8 (NANOG‐pseudogene) plays a role in tumorigenesis. Herein, we…”
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FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation by Babaei-Jadidi, Roya, Li, Ningning, Saadeddin, Anas, Spencer-Dene, Bradley, Jandke, Anett, Muhammad, Belal, Ibrahim, ElSayed E, Muraleedharan, Ranjithmenon, Abuzinadah, Mohammed, Davis, Hayley, Lewis, Annabelle, Watson, Susan, Behrens, Axel, Tomlinson, Ian, Nateri, Abdolrahman Shams

“…The Fbxw7 (F-box/WD repeat-containing protein 7; also called CDC4, Sel10, Ago, and Fbw7) component of the SCF (Skp1/Cullin/F-box protein) E3 ubiquitin ligase…”
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The Links between Transcription, β-catenin/JNK Signaling, and Carcinogenesis by Anas Saadeddin, Roya Babaei-Jadidi, Bradley Spencer-Dene, Abdolrahman Shams Nateri

“…Interactions between transcription and signaling are fundamentally important for understanding both the structure and function of genetic pathways and their…”
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Synthesis and Structure–Activity Relationships of the Novel Antimalarials 5‑Pyridinyl-4(1H)‑Pyridones by Bueno, José M, Calderon, Félix, Chicharro, Jesús, De la Rosa, Juan C, Díaz, Beatriz, Fernández, Jorge, Fiandor, José M, Fraile, María T, García, Mercedes, Herreros, Esperanza, García-Pérez, Adolfo, Lorenzo, Milagros, Mallo, Araceli, Puente, Margarita, Saadeddin, Anas, Ferrer, Santiago, Angulo-Barturen, Iñigo, Burrows, Jeremy N, León, María L

“…Malaria is still one of the most prevalent parasitic infections in the world, with half of the world’s population at risk for malaria. The effectiveness of…”
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Population pharmacokinetic analysis of vancomycin in neonates. A new proposal of initial dosage guideline by Marqués‐Miñana, María‐Remedios, Saadeddin, Anas, Peris, José‐Esteban

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Vancomycin is a glycopeptide antibiotic commonly used to treat resistant gram‐positive infections in neonates. While…”
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The complexities of hydrolytic enzymes from the termite digestive system by Saadeddin, Anas

“…The main challenge in second generation bioethanol production is the efficient breakdown of cellulose to sugar monomers (hydrolysis). Due to the recalcitrant…”
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The cellulolytic system of Thermobifida fusca by Gomez del Pulgar, Eva Maria, Saadeddin, Anas

“…The process of bioethanol production from biomass comprises pretreatments and enzyme-mediated hydrolysis to convert lignocellulose into fermentable sugars…”
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Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model by Saadeddin, Anas, Purohit, Vivek, Huh, Yeamin, Wong, Mei, Maulny, Aurelia, Dowty, Martin E., Sagawa, Kazuko

“…Ritlecitinib, an orally available Janus kinase 3 and tyrosine kinase inhibitor being developed for the treatment of alopecia areata (AA), is highly soluble…”
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Pharmacokinetics of the time-dependent elimination of all-trans-retinoic acid in rats by Saadeddin, Anas, Torres-Molina, Francisca, Cárcel-Trullols, Jaime, Araico, Amparo, Peris, José-Esteban

“…The time-dependent elimination kinetics of all-trans-retinoic acid (ATRA) has been associated with autoinduction of its metabolism and has led to the…”
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Correction: Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model by Saadeddin, Anas, Purohit, Vivek, Huh, Yeamin, Wong, Mei, Maulny, Aurelia, Dowty, Martin E., Sagawa, Kazuko

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Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites by Matralis, Alexios N, Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J, Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A, Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A

“…One of the attractive properties of artemisinins is their extremely fast-killing capability, quickly relieving malaria symptoms. Nevertheless, the unique…”
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Recent trends in ionic liquid (IL) tolerant enzymes and microorganisms for biomass conversion by Portillo, Maria Del Carmen, Saadeddin, Anas

“…Second generation biofuel production depends on lignocellulosic (LC) biomass transformation into simple sugars and their subsequent fermentation into alcohols…”
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FLYWCH1, a Novel Suppressor of Nuclear β-Catenin, Regulates Migration and Morphology in Colorectal Cancer by Muhammad, Belal A, Almozyan, Sheema, Babaei-Jadidi, Roya, Onyido, Emenike K, Saadeddin, Anas, Kashfi, Seyed Hossein, Spencer-Dene, Bradley, Ilyas, Mohammad, Lourdusamy, Anbarasu, Behrens, Axel, Nateri, Abdolrahman S

“…Wnt/β-catenin signaling plays a critical role during development of both normal and malignant colorectal cancer tissues. Phosphorylation of β-catenin protein…”
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Living biointerfaces based on non-pathogenic bacteria to direct cell differentiation by Rodrigo-Navarro, Aleixandre, Rico, Patricia, Saadeddin, Anas, Garcia, Andres J., Salmeron-Sanchez, Manuel

“…Genetically modified Lactococcus lactis , non-pathogenic bacteria expressing the FNIII 7-10 fibronectin fragment as a protein membrane have been used to create…”
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Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130) by Revert-Ros, Francisco, López-Pascual, Ernesto, Granero-Moltó, Froilán, Macías, Jesús, Breyer, Richard, Zent, Roy, Hudson, Billy G, Saadeddin, Anas, Revert, Fernando, Blasco, Raül, Navarro, Carmen, Burks, Deborah, Saus, Juan

“…Goodpasture antigen-binding protein-1 (GPBP-1) is an exportable non-conventional Ser/Thr kinase that regulates glomerular basement membrane collagen…”
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Functional Living Biointerphases by Saadeddin, Anas, Rodrigo-Navarro, Aleixandre, Monedero, Vicente, Rico, Patricia, Moratal, David, González-Martín, María Luisa, Navarro, David, García, Andrés J., Salmerón-Sánchez, Manuel

“…Lactococcus lactis is modified to express a fibronectin fragment (FNIII7‐10) as a membrane protein. This interphase, based on a living system, can be further…”
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FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation by Babaei-Jadidi, Roya, Li, Ningning, Saadeddin, Anas, Spencer-Dene, Bradley, Jandke, Anett, Muhammad, Belal, Ibrahim, ElSayed E., Muraleedharan, Ranjithmenon, Abuzinadah, Mohammed, Davis, Hayley, Lewis, Annabelle, Watson, Susan, Behrens, Axel, Tomlinson, Ian, Nateri, Abdolrahman Shams

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Goodpasture Antigen-binding Protein (GPBP) Directs Myofibril Formation by Revert-Ros, Francisco, López-Pascual, Ernesto, Granero-Moltó, Froilán, Macías, Jesús, Breyer, Richard, Zent, Roy, Hudson, Billy G., Saadeddin, Anas, Revert, Fernando, Blasco, Raül, Navarro, Carmen, Burks, Deborah, Saus, Juan

“…Goodpasture antigen-binding protein-1 (GPBP-1) is an exportable non-conventional Ser/Thr kinase that regulates glomerular basement membrane collagen…”
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Effect of cyclosporine A on the tissue distribution and pharmacokinetics of etoposide by CARCEL-TRULLOLS, Jaime, TORRES-MOLINA, Francisca, ARAICO, Amparo, SAADEDDIN, Anas, PERIS, José Esteban

“…Cyclosporine A (CyA) is able to inhibit P-glycoprotein (P-gp) and to increase cytotoxicity of some anticancer drugs, including etoposide. However, the effect…”
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Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all- trans-retinoic acid by Saadeddin, Anas, Torres-Molina, Francisca, Cárcel-Trullols, Jaime, Araico, Amparo, Peris, José Esteban

“…Diethyl dithiocarbamate (DEDTC) has been reported to be a more powerful inhibitor of all- trans-retinoic acid (ATRA) in vitro metabolism than the…”
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