Search Results - "Saade, George R."

Amniotic Fluid Exosome Proteomic Profile Exhibits Unique Pathways of Term and Preterm Labor by Dixon, C Luke, Sheller-Miller, Samantha, Saade, George R, Fortunato, Stephen J, Lai, Andrew, Palma, Carlos, Guanzon, Dominic, Salomon, Carlos, Menon, Ramkumar

“…Our objective was to determine the amniotic fluid-derived exosomal proteomic profile in patients who had spontaneous preterm birth (PTB) or preterm premature…”
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HMGB1 promotes a p38MAPK associated non-infectious inflammatory response pathway in human fetal membranes by Bredeson, Sarah, Papaconstantinou, John, Deford, James H, Kechichian, Talar, Syed, Tariq A, Saade, George R, Menon, Ramkumar

“…Spontaneous preterm birth (PTB) and preterm prelabor rupture of membranes (pPROM) are major pregnancy complications often associated with a fetal inflammatory…”
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Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus by Facco, Francesca L., Parker, Corette B., Reddy, Uma M., Silver, Robert M., Koch, Matthew A., Louis, Judette M., Basner, Robert C., Chung, Judith H., Nhan-Chang, Chia-Ling, Pien, Grace W., Redline, Susan, Grobman, William A., Wing, Deborah A., Simhan, Hyagriv N., Haas, David M., Mercer, Brian M., Parry, Samuel, Mobley, Daniel, Hunter, Shannon, Saade, George R., Schubert, Frank P., Zee, Phyllis C.

“…OBJECTIVE:To estimate whether sleep-disordered breathing during pregnancy is a risk factor for the development of hypertensive disorders of pregnancy and…”
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High-fructose diet in pregnancy leads to fetal programming of hypertension, insulin resistance, and obesity in adult offspring by Saad, Antonio F., MD, Dickerson, Joshua, Kechichian, Talar B., MS, Yin, Huaizhi, Gamble, Phyllis, Salazar, Ashley, Patrikeev, Igor, PhD, Motamedi, Massoud, PhD, Saade, George R., MD, Costantine, Maged M., MD

“…Background Consumption of fructose-rich diets in the United States is on the rise and thought to be associated with obesity and cardiometabolic diseases…”
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An update on the use of massive transfusion protocols in obstetrics by Pacheco, Luis D., MD, Saade, George R., MD, Costantine, Maged M., MD, Clark, Steven L., MD, Hankins, Gary D.V., MD

“…Obstetrical hemorrhage remains a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described…”
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Blood pressure trajectory and category and risk of hypertensive disorders of pregnancy in nulliparous women by Hauspurg, Alisse, Parry, Samuel, Mercer, Brian M., Grobman, William, Hatfield, Tamera, Silver, Robert M., Parker, Corette B., Haas, David M., Iams, Jay D., Saade, George R., Wapner, Ronald J., Reddy, Uma M., Simhan, Hyagriv

“…Recently updated American College of Cardiology/ American Heart Association (ACC/AHA) guidelines redefine blood pressure categories as stage 1 hypertension…”
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Maternal Marijuana Use, Adverse Pregnancy Outcomes and Neonatal Morbidity by Metz, Torri D., MD, MS, Allshouse, Amanda A., Ms, Hogue, Carol J. Rowland, PhD, MPH, Goldenberg, Robert L., MD, Dudley, Donald J., MD, Varner, Michael W., MD, Conway, Deborah L., MD, Saade, George R., MD, Silver, Robert M., MD

“…Abstract Background The NICHD Stillbirth Collaborative Research Network (SCRN) previously demonstrated an association between stillbirth and maternal marijuana…”
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Chorioamniotic membrane senescence: a signal for parturition? by Behnia, Faranak, MD, Taylor, Brandie D., PhD, Woodson, Michael, PhD, Kacerovsky, Marian, MD, PhD, Hawkins, Hal, MD, PhD, Fortunato, Stephen J., MD, Saade, George R., MD, Menon, Ramkumar, MS, PhD

“…Objective Senescence is an important biological phenomenon involved in both physiologic and pathologic processes. We propose that chorioamniotic membrane…”
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Fetal imaging: Executive Summary of a Joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop by Reddy, Uma M., MD, MPH, Abuhamad, Alfred Z., MD, Levine, Deborah, MD, Saade, George R., MD

“…Given that practice variation exists in the frequency and performance of ultrasound and magnetic resonance imaging in pregnancy, the Eunice Kennedy Shriver…”
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Objectively measured short sleep duration and later sleep midpoint in pregnancy are associated with a higher risk of gestational diabetes by Facco, Francesca L., MD., MSCI, Grobman, William A., MD, MBA, Reid, Kathryn J., PhD, Parker, Corette B., DrPH, Hunter, Shannon M., MS, Silver, Robert M., MD, Basner, Robert C., MD, Saade, George R., MD, Pien, Grace W., MD, MSCE, Manchanda, Shalini, MD, Louis, Judette M., MD., PhD, Nhan-Chang, Chia-Ling, MD, Chung, Judith H., MD, PhD, Wing, Deborah A., MD, MBA, Simhan, Hyagriv N., MD, Haas, David M., MD, MS, Iams, Jay, MD, Parry, Samuel, MD, Zee, Phyllis C., MD., PhD

“…Abstract Background Experimental and epidemiologic data suggest that among non-pregnant adults, sleep duration may be an important risk factor for chronic…”
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Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition? by Polettini, Jossimara, Behnia, Faranak, Taylor, Brandie D, Saade, George R, Taylor, Robert N, Menon, Ramkumar

“…Oxidative stress (OS)-induced senescence of the amniochorion has been associated with parturition at term. We investigated whether telomere fragments shed into…”
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A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b) by Haas, David M., MD, MS, Parker, Corette B., DrPH, Wing, Deborah A., MD, Parry, Samuel, MD, Grobman, William A., MD, MBA, Mercer, Brian M., MD, Simhan, Hyagriv N., MD, Hoffman, Matthew K., MD, Silver, Robert M., MD, Wadhwa, Pathik, MD, PhD, Iams, Jay D., MD, Koch, Matthew A., MD, PhD, Caritis, Steve N., MD, Wapner, Ronald J., MD, Esplin, M. Sean, MD, Elovitz, Michal A., MD, Foroud, Tatiana, PhD, Peaceman, Alan M., MD, Saade, George R., MD, Willinger, Marian, PhD, Reddy, Uma M., MD, MPH

“…Objective The primary aim of the “Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be” is to determine maternal characteristics, which include…”
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Elevated Testosterone Reduces Uterine Blood Flow, Spiral Artery Elongation, and Placental Oxygenation in Pregnant Rats by Gopalakrishnan, Kathirvel, Mishra, Jay S, Chinnathambi, Vijayakumar, Vincent, Kathleen L, Patrikeev, Igor, Motamedi, Massoud, Saade, George R, Hankins, Gary D, Sathishkumar, Kunju

“…Elevated maternal testosterone levels are shown to cause fetal growth restriction, eventually culminating in sex-specific adult-onset hypertension that is more…”
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Senescence of primary amniotic cells via oxidative DNA damage by Menon, Ramkumar, Boldogh, Istvan, Urrabaz-Garza, Rheanna, Polettini, Jossimara, Syed, Tariq Ali, Saade, George R, Papaconstantinou, John, Taylor, Robert N

“…Oxidative stress is a postulated etiology of spontaneous preterm birth (PTB) and preterm prelabor rupture of the membranes (pPROM); however, the precise…”
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Periconceptional diet quality is associated with gestational diabetes risk and glucose concentrations among nulliparous gravidas by Lindsay, Karen L., Milone, Gina F., Grobman, William A., Haas, David M., Mercer, Brian M., Simhan, Hyagriv N., Saade, George R., Silver, Robert M., Chung, Judith H.

“…Background Gestational diabetes mellitus (GDM) and elevated glucose concentrations below the threshold for GDM diagnosis have been associated with adverse…”
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Interleukin (IL)-6: A Friend or Foe of Pregnancy and Parturition? Evidence From Functional Studies in Fetal Membrane Cells by Omere, Chasey, Richardson, Lauren, Saade, George R, Bonney, Elizabeth A, Kechichian, Talar, Menon, Ramkumar

“…Protection of the fetus within the amniotic sac is primarily attained by remodeling fetal membrane (amniochorion) cells through cyclic epithelial to…”
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Predictors of sleep-disordered breathing in pregnancy by Louis, Judette M., Koch, Matthew A., Reddy, Uma M., Silver, Robert M., Parker, Corette B., Facco, Francesca L., Redline, Susan, Nhan-Chang, Chia-Ling, Chung, Judith H., Pien, Grace W., Basner, Robert C., Grobman, William A., Wing, Deborah A., Simhan, Hyagriv N., Haas, David M., Mercer, Brian M., Parry, Samuel, Mobley, Daniel, Carper, Benjamin, Saade, George R., Schubert, Frank P., Zee, Phyllis C.

“…Sleep-disordered breathing (SDB) is common in pregnancy, but there are limited data on predictors. The objective of this study was to develop predictive models…”
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Fetal growth and risk of stillbirth: a population-based case-control study by Bukowski, Radek, Hansen, Nellie I, Willinger, Marian, Reddy, Uma M, Parker, Corette B, Pinar, Halit, Silver, Robert M, Dudley, Donald J, Stoll, Barbara J, Saade, George R, Koch, Matthew A, Rowland Hogue, Carol J, Varner, Michael W, Conway, Deborah L, Coustan, Donald, Goldenberg, Robert L

“…Stillbirth is strongly related to impaired fetal growth. However, the relationship between fetal growth and stillbirth is difficult to determine because of…”
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Altered fetal growth, placental abnormalities, and stillbirth by Bukowski, Radek, Hansen, Nellie I, Pinar, Halit, Willinger, Marian, Reddy, Uma M, Parker, Corette B, Silver, Robert M, Dudley, Donald J, Stoll, Barbara J, Saade, George R, Koch, Matthew A, Hogue, Carol, Varner, Michael W, Conway, Deborah L, Coustan, Donald, Goldenberg, Robert L

“…Worldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk…”
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Comparing variation in hospital rates of cesarean delivery among low-risk women using 3 different measures by Armstrong, Joanne C., MD, MPH, Kozhimannil, Katy B., PhD, MPA, McDermott, Patricia, RN, Saade, George R., MD, Srinivas, Sindhu K., MD, MSCE

“…This report describes the development of a measure of low-risk cesarean delivery by the Society for Maternal-Fetal Medicine (SMFM). Safely lowering the…”
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