Search Results - "Saad, Moayad A."

Incubation at 32.5°C and above causes malformations in the zebrafish embryo by Pype, Casper, Verbueken, Evy, Saad, Moayad A., Casteleyn, Christophe R., Van Ginneken, Chris J., Knapen, Dries, Van Cruchten, Steven J.

“…Zebrafish embryos are increasingly used for developmental toxicity screening of candidate drugs and are occasionally co-incubated with a metabolic activation…”
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In Vitro Biotransformation of Two Human CYP3A Probe Substrates and Their Inhibition during Early Zebrafish Development by Verbueken, Evy, Alsop, Derek, Saad, Moayad A, Pype, Casper, Van Peer, Els M, Casteleyn, Christophe R, Van Ginneken, Chris J, Wilson, Joanna, Van Cruchten, Steven J

“…At present, the zebrafish embryo is increasingly used as an alternative animal model to screen for developmental toxicity after exposure to xenobiotics. Since…”
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Antioxidants reduce reactive oxygen species but not embryotoxicity in the metabolic Danio rerio test (mDarT) by Pype, Casper, Verbueken, Evy, Saad, Moayad A., Bars, Chloé, Van Ginneken, Chris J., Knapen, Dries, Van Cruchten, Steven J.

“…•Reactive oxygen species (ROS) are present in the metabolic Danio rerio test (mDarT).•Antioxidants reduce ROS in the coincubation medium of the mDarT but not…”
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Optimization of the co-incubation conditions in the mDarT assay by Pype, Casper, Verbueken, Evy, Saad, Moayad A., Van Peer, Els, Casteleyn, Christophe, Van Ginneken, Chris J., Knapen, Dries, Van Cruchten, Steven J.

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In vitro characterization and ontogeny of CYP3A activity in the zebrafish by Verbueken, Evy, Saad, Moayad A., Pype, Casper, Casteleyn, Christophe, Van Ginneken, Chris J., Van Cruchten, Steven J.

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Embryotoxicity in the mDarT: Is oxidative stress the key driver? by Pype, Casper, Verbueken, Evy, Saad, Moayad A., Casteleyn, Christophe, Van Ginneken, Chris J., Knapen, Dries, Van Cruchten, Steven J.

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Ontogeny of drug metabolism in the zebrafish: An in vitro study using human CYP-specific substrates by Saad, Moayad A., Verbueken, Evy, Pype, Casper, Casteleyn, Christophe R., Van Ginneken, Chris J., Maes, Louis, Cos, Paul, Van Cruchten, Steven J.

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Incubation at 32.5 degree C and above causes malformations in the zebrafish embryo by Pype, Casper, Verbueken, Evy, Saad, Moayad A, Casteleyn, Christophe R, Van Ginneken, Chris J, Knapen, Dries, Van Cruchten, Steven J

“…Zebrafish embryos are increasingly used for developmental toxicity screening of candidate drugs and are occasionally co-incubated with a metabolic activation…”
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Ontogeny of CYP3A in the liver of the Göttingen minipig: An immunohistochemical and functional evaluation by Van Peer, Els M., Verbueken, Evy, Saad, Moayad A., Pype, Casper, Casteleyn, Christophe R., Van Ginneken, Chris J., Van Cruchten, Steven J.

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Lack of in vitro CYP3A activity in early zebrafish embryos by Verbueken, Evy, Saad, Moayad A., Pype, Casper, Van Peer, Els M., Casteleyn, Christophe R., Van Ginneken, Chris J., Van Cruchten, Steven J.

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In vitro CYP1A activity in the zebrafish: Effects of gender, temperature and developmental stage by Saad, Moayad A., Verbueken, Evy, Pype, Casper, Van Peer, Els M., Casteleyn, Christophe R., Van Ginneken, Chris J., Van Cruchten, Steven J.M.

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Temperatures of 32.5 °C and above impact zebrafish embryonic development by Pype, Casper, Verbueken, Evy, Saad, Moayad A., Van Peer, Els M., Casteleyn, Christophe R., Van Ginneken, Chris J., Knapen, Dries, Van Cruchten, Steven J.

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