Search Results - "Saad, Heba M"
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AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats
Published in Molecules (Basel, Switzerland) (15-01-2020)“…For hepatic failure, stem cell transplantation has been chosen as an alternative therapy, especially for mesenchymal stem cells (MSCs). The aim of this study…”
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Bee Venom Accelerates Wound Healing in Diabetic Mice by Suppressing Activating Transcription Factor-3 (ATF-3) and Inducible Nitric Oxide Synthase (iNOS)-Mediated Oxidative Stress and Recruiting Bone Marrow-Derived Endothelial Progenitor Cells
Published in Journal of cellular physiology (01-10-2016)“…Multiple mechanisms contribute to impaired diabetic wound healing including impaired neovascularization and deficient endothelial progenitor cell (EPC)…”
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Preconditioning of Adipose-Derived Mesenchymal Stem-Like Cells with Eugenol Potentiates Their Migration and Proliferation In Vitro and Therapeutic Abilities in Rat Hepatic Fibrosis
Published in Molecules (Basel, Switzerland) (26-04-2020)“…Mesenchymal stem cells (MSCs) have considerable therapeutic abilities in various disorders, including hepatic fibrosis. They may be affected with different…”
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Oral administration of Moringa oleifera leaf powder relieves oxidative stress, modulates mucosal immune response and cecal microbiota after exposure to heat stress in New Zealand White rabbits
Published in Journal of animal science and biotechnology (12-05-2021)“…Heat stress (HS) disrupts the gut barrier allowing the uptake of lipopolysaccharide (LPS) and leads to an inflammatory response and changes in gut microbiota…”
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5
Yarrow oil ameliorates ulcerative colitis in mice model via regulating the NF-κB and PPAR-γ pathways
Published in Intestinal research (01-04-2021)“…Background/Aims: Ulcerative colitis (UC) is a chronic inflammatory disorder with indefinite etiology; however, environmental, genetic, immune factors and…”
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Increased Levels of Type 1 Interferon in a Type 1 Diabetic Mouse Model Induce the Elimination of B Cells from the Periphery by Apoptosis and Increase their Retention in the Spleen
Published in Cellular physiology and biochemistry (01-01-2015)“…Background: The autoimmune disease type 1 diabetes mellitus (T1D) is associated with a defect in the immune response, which increases susceptibility to…”
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Beta 2 Adrenergic Receptor Genetic Polymorphisms in Bronchial Asthma: Relationship to Disease Risk, Severity, and Treatment Response
Published in Lung (01-12-2018)“…Background The β 2 -adrenergic receptor gene is one of the most extensively studied genes with respect to asthma prevalence and severity. The Arg16Gly and…”
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Blocking Type I Interferon Signaling Rescues Lymphocytes from Oxidative Stress, Exhaustion, and Apoptosis in a Streptozotocin-Induced Mouse Model of Type I Diabetes
Published in Oxidative medicine and cellular longevity (01-01-2013)“…Elevated levels of type I interferon (IFN) during type 1 diabetes mellitus (T1D) are associated with a defective immune response. In the present study, we…”
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The immune-modulatory role of MSCs exerted by PI3K/AKT signaling pathway in kidney tissue after cyclophosphamide
Published in African health sciences (01-12-2023)“…Cyclophosphamide (CP) is one of the most effective immunosuppressive agents. To understand the mechanisms used by the CP and MSCs in the kidney, we…”
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The relationship of HLA-G 14-bp insertion/deletion genetic polymorphism to the risk of multiple sclerosis and its clinical phenotypes
Published in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery (11-05-2021)“…BackgroundHuman leukocyte antigen (HLA)-G molecule has been suggested to have a potential immunomodulatory role in multiple sclerosis (MS). Genetic variant…”
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Blocking Type I Interferon (IFN) Signaling Impairs Antigen Responsiveness of Circulating Lymphocytes and Alters Their Homing to Lymphoid Organs: Protective Role of Type I IFN
Published in Cellular physiology and biochemistry (01-01-2010)“…Background: We recently demonstrated that type I Interferon (IFN) rescues in vitro, human B-lymphocytes from apoptosis via PI3Kδ/Akt, Rho-A, NFĸB and…”
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Morphology of cat vomeronasal organ non-sensory epithelium during postnatal development
Published in Anatomy & cell biology (01-03-2017)“…The vomeronasal organ has an important role in mammal's social and sexual behaviours. In addition, it mediates defensive behavior through detection of protein…”
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Sensory Innervation of the Female Human Umbilical Skin: Morphological Studies
Published in Ultrastructural pathology (01-02-2013)“…Background: Sensory stimuli are conducted by several cutaneous sensory nerves and tactile corpuscles. The latter are specialized sensory organs that represent…”
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Time-dependent Morphological and Biochemical Changes following Cutaneous Thermal Burn Injury and Their Modulation by Copper Nicotinate Complex: An Animal Model
Published in Ultrastructural pathology (01-10-2012)“…Background: Thermal tissue injury is partly mediated by reactive oxygen metabolites. Oxygen free radicals are contributory to local tissue damage following…”
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Periostin expression and characters of human adipose tissue-derived mesenchymal stromal cells were aberrantly affected by in vitro cultivation
Published in Stem cell investigation (2019)“…Human adipose tissue-derived mesenchymal stromal cells (AD-MSCs) have been under focus in regenerative medicine since their discovery as a suitable source of…”
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The possible protective role of barley seeds on the spleen after administration of glucocorticoids in adult albino rats: A histological and immunohistochemical study
Published in The journal of microscopy & ultrastructure (01-10-2019)“…Background: Glucocorticoids (GCs) are the main treatment strategy in many autoimmune disease and inflammatory diseases; however, they have immunosuppressive…”
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The immunomodulating and antioxidant activity of fucoidan on the splenic tissue of rats treated with cyclosporine A
Published in Journal of basic & applied zoology (01-10-2013)“…Cyclosporine A (CsA), a potent immunosuppressive agent, has several adverse effects on different organs including the spleen. Fucoidan is a sulfated…”
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Molecular characterization of dromedary camel potential fertility: A new approach
Published in Small ruminant research (01-01-2019)“…•Expression of hypothetical fertility-related molecular markers in camels was investigated during and out of rut.•Three fertility categorize of camels were…”
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Prevalence of Childhood Obesity Among Children and Adolescents in Saudi Arabia: A Systematic Review
Published in Curēus (Palo Alto, CA) (01-09-2024)“…Childhood obesity is a growing public health concern worldwide, with significant implications for long-term health outcomes. Thus, the aim of this study is to…”
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The Impact of Royal Jelly against Hepatic Ischemia/Reperfusion-Induced Hepatocyte Damage in Rats: The Role of Cytoglobin, Nrf-2/HO-1/COX-4, and P38-MAPK/NF-κB-p65/TNF-α Signaling Pathways
Published in Current molecular pharmacology (2021)“…The present study was conducted to elucidate the underlying molecular mechanism as well as the potential hepatoprotective effects of royal jelly (RJ) against…”
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