Search Results - "Saad, Faten"

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    Elucidation of IgH 3′ region regulatory role during class switch recombination via germline deletion by Saintamand, Alexis, Rouaud, Pauline, Saad, Faten, Rios, Géraldine, Cogné, Michel, Denizot, Yves

    Published in Nature communications (11-05-2015)
    “…In mature B cells, class switch recombination (CSR) replaces the expressed constant Cμ gene with a downstream C H gene. How the four transcriptional enhancers…”
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    Journal Article
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    Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region by Rouaud, Pauline, Saintamand, Alexis, Saad, Faten, Carrion, Claire, Lecardeur, Sandrine, Cogné, Michel, Denizot, Yves

    Published in The Journal of experimental medicine (05-05-2014)
    “…Classical class-switch recombination (cCSR) substitutes the Cμ gene with Cγ, Cε, or Cα, thereby generating IgG, IgE, or IgA classes, respectively. This…”
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    Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients by Saad, Faten, Gadallah, Mahmoud, Daif, Ahmed, Bedair, Nahed, Sakr, Moustafa A.

    “…BackgroundHeparanase activity was found to be included in human cancer development and growth. Heparanase (HPSE) gene single nucleotide polymorphisms (SNPs)…”
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    Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas by Ghazzaui, Nour, Saintamand, Alexis, Issaoui, Hussein, Saad, Faten, Denizot, Yves

    Published in Oncotarget (21-06-2016)
    “…Functional B-cells are essential for the formation of oil granulomas. The IgH 3' regulatory region (3'RR) activates important check-points during B-cell…”
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    Journal Article
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    The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc mice by Saad, Faten, Saintamand, Alexis, Cogné, Michel, Denizot, Yves

    Published in Oncotarget (21-08-2015)
    “…The IgH 3'regulatory region (3'RR), encompassing the four transcriptional enhancers hs3a-hs1,2-hs3b-hs4, has a key role on class switch recombination, somatic…”
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    Journal Article
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    The IgH 3′ regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate by Saintamand, Alexis, Rouaud, Pauline, Garot, Armand, Saad, Faten, Carrion, Claire, Oblet, Christelle, Cogné, Michel, Pinaud, Eric, Denizot, Yves

    Published in Oncotarget (10-03-2015)
    “…We report that the IgH 3' regulatory region (3'RR) has no role on μ chain transcription and pre-BCR expression in B cell progenitors. In contrast, analysis of…”
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    Ex vivo model of congenital cytomegalovirus infection and new combination therapies by Morère, L, Andouard, D, Labrousse, F, Saade, F, Calliste, C.-A, Cotin, S, Aubard, Y, Rawlinson, W.D, Esclaire, F, Hantz, S, Ploy, M.-C, Alain, S

    Published in Placenta (Eastbourne) (01-01-2015)
    “…Abstract Introduction Congenital human cytomegalovirus (HCMV) infection is a major public health problem due to severe sequelae in the fetus and newborns…”
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    The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate by Saintamand, Alexis, Rouaud, Pauline, Garot, Armand, Saad, Faten, Carrion, Claire, Oblet, Christelle, Cogné, Michel, Pinaud, Eric, Denizot, Yves

    Published in Oncotarget (10-03-2015)
    “…We report that the IgH 3' regulatory region (3'RR) has no role on μ chain transcription and pre-BCR expression in B cell progenitors. In contrast, analysis of…”
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    Journal Article
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    Targeting the oncogene B lymphoma deregulator IgH 3' regulatory region does not impede the in vivo inflammatory response in mice by Saad, Faten, Saintamand, Alexis, Rouaud, Pauline, Denizot, Yves

    Published in Oncoscience (19-09-2014)
    “…The IgH 3' regulatory region (3'RR), encompassing the four transcriptional enhancers hs3a-hs1,2-hs3b-hs4, is a potent lymphoma oncogene deregulator but its…”
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