Search Results - "Saab, Sally"
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Curing mosquitoes with genetic approaches for malaria control
Published in Trends in parasitology (01-06-2024)“…A population modification approach involves spreading genes/elements through the populations to make mosquitoes refractory to the parasite.Parasite…”
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Insight into the structural hierarchy of the protease cascade that regulates the mosquito melanization response
Published in Microbes and infection (01-01-2024)“…Serine protease cascades regulate important insect immune responses, including melanization and Toll pathway activation. In the context of melanization,…”
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Late sporogonic stages of Plasmodium parasites are susceptible to the melanization response in Anopheles gambiae mosquitoes
Published in Frontiers in cellular and infection microbiology (01-08-2024)“…The malaria-causing parasites have to complete a complex infection cycle in the mosquito vector that also involves attack by the insect's innate immune system,…”
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The environment and species affect gut bacteria composition in laboratory co-cultured Anopheles gambiae and Aedes albopictus mosquitoes
Published in Scientific reports (25-02-2020)“…The midgut microbiota of disease vectors plays a critical role in the successful transmission of human pathogens. The environment influences the microbiota…”
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CLIPB4 Is a Central Node in the Protease Network that Regulates Humoral Immunity in Anopheles gambiae Mosquitoes
Published in Journal of innate immunity (01-01-2023)“…Abstract Insect humoral immune responses are regulated in part by protease cascades, whose components circulate as zymogens in the hemolymph. In mosquitoes,…”
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Spatiotemporal Dynamics of Immune Cells in Early Left Ventricular Remodeling After Acute Myocardial Infarction in Mice
Published in Journal of cardiovascular pharmacology (01-02-2020)“…Myocardial infarction remains a leading cause of morbidity and death. Insufficient delivery of oxygen to the myocardium sets into play a complicated process of…”
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CLIPB10 is a Terminal Protease in the Regulatory Network That Controls Melanization in the African Malaria Mosquito Anopheles gambiae
Published in Frontiers in cellular and infection microbiology (15-01-2021)“…Humoral immune responses in animals are often tightly controlled by regulated proteolysis. This proteolysis is exerted by extracellular protease cascades,…”
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