Search Results - "Saïagh, Soraya"

Value of large scale expansion of tumor infiltrating lymphocytes in a compartmentalised gas-permeable bag: interests for adoptive immunotherapy by Zuliani, Thomas, David, Julien, Bercegeay, Sylvain, Pandolfino, Marie-Christine, Rodde-Astier, Isabelle, Khammari, Amir, Coissac, Cécile, Delorme, Bruno, Saïagh, Soraya, Dréno, Brigitte

“…Adoptive cell therapy (ACT) has emerged as an effective treatment for patients with metastatic melanoma. However, there are several logistical and safety…”
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Preclinical Assessment of Autologous Tolerogenic Dendritic Cells From End-stage Renal Disease Patients by Bouchet-Delbos, Laurence, Even, Amandine, Varey, Emilie, Saïagh, Soraya, Bercegeay, Sylvain, Braudeau, Cécile, Dréno, Brigitte, Blancho, Gilles, Josien, Régis, Cuturi, Maria-Cristina, Moreau, Aurélie

“…BACKGROUND:Kidney transplantation is the therapeutic of choice for patients suffering from kidney failure. Whilst immunosuppressive drugs can control graft…”
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Tumor infiltrating lymphocytes as adjuvant treatment in stage III melanoma patients with only one invaded lymph node after complete resection: results from a multicentre, randomized clinical phase III trial by Khammari, Amir, Nguyen, Jean-Michel, Leccia, Marie-Thérèse, Guillot, Bernard, Saiagh, Soraya, Pandolfino, Marie-Christine, Knol, Anne-Chantal, Quéreux, Gaëlle, Chiffolettau, Anne, Labarrière, Nathalie, Dréno, Brigitte

“…Background Adoptive tumor-infiltrating lymphocytes (TIL) therapy and interleukin-2 (IL-2) have been investigated in melanoma. Aim To confirm previously…”
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Fetal fibroblasts and keratinocytes with immunosuppressive properties for allogeneic cell-based wound therapy by Zuliani, Thomas, Saiagh, Soraya, Knol, Anne-Chantal, Esbelin, Julie, Dréno, Brigitte

“…Fetal skin heals rapidly without scar formation early in gestation, conferring to fetal skin cells a high and unique potential for tissue regeneration and scar…”
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NIVO-TIL: combination anti-PD-1 therapy and adoptive T-cell transfer in untreated metastatic melanoma: an exploratory open-label phase I trial by L'Orphelin, Jean-Matthieu, Lancien, Ugo, Nguyen, Jean-Michel, Coronilla, Francisco J.S., Saiagh, Soraya, Cassecuel, Julie, Boussemart, Lise, Dompmartin, Anne, Dréno, Brigitte

“…I the proliferation of intra-tumour CD8+ T cells is directly correlated with the clinical response, making tumour-infiltrating lymphocytes (TILs) a treatment…”
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A Phase I/IIa study of autologous tolerogenic dendritic cells immunotherapy in kidney transplant recipients by Moreau, Aurélie, Kervella, Delphine, Bouchet-Delbos, Laurence, Braudeau, Cécile, Saïagh, Soraya, Guérif, Pierrick, Limou, Sophie, Moreau, Anne, Bercegeay, Sylvain, Streitz, Mathias, Sawitzki, Birgit, James, Ben, Harden, Paul N, Game, David, Tang, Qizhi, Markmann, James F, Roberts, Ian S D, Geissler, Edward K, Dréno, Brigitte, Josien, Régis, Cuturi, Maria-Cristina, Blancho, Gilles

“…Kidney transplant survival is shortened by chronic rejection and side effects of standard immunosuppressive drugs. Cell-based immunotherapy with tolerogenic…”
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Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients by Dréno, Brigitte, Khammari, Amir, Fortun, Agnès, Vignard, Virginie, Saiagh, Soraya, Beauvais, Tiffany, Jouand, Nicolas, Bercegay, Sylvain, Simon, Sylvain, Lang, François, Labarrière, Nathalie

“…Adoptive cell transfer (ACT) of tumor-specific T lymphocytes represents a relevant therapeutic strategy to treat metastatic melanoma patients. Ideal T-cells…”
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CICAFAST: comparison of a biological dressing composed of fetal fibroblasts and keratinocytes on a split-thickness skin graft donor site versus a traditional dressing: a randomized controlled trial by Poinas, Alexandra, Perrot, Pierre, Lorant, Judith, Nerrière, Olivier, Nguyen, Jean-Michel, Saiagh, Soraya, Frenard, Cécile, Leduc, Audrey, Malard, Olivier, Espitalier, Florent, Duteille, Franck, Chiffoleau, Anne, Vrignaud, Florence, Khammari, Amir, Dréno, Brigitte

“…Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary…”
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Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients by Bedane, Christophe, Basset-Seguin, Nicole, Khammari, A., Dreno, B., Saïagh, S., Pandolfino, Marie-Christine, Brocard, Anabelle, Peuvrel, Lucie, Quéreux, Gaëlle, Volteau, Christelle, Knol, Anne-Chantal, Saint-Jean, Mélanie, Nguyen, Jean-Michel

“…Immunotherapy for melanoma includes adoptive cell therapy with autologous tumor-infiltrating lymphocytes (TILs). This monocenter retrospective study was…”
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A phase I/II feasibility vaccine study by autologous leukemic apoptotic corpse-pulsed dendritic cells for elderly AML patients by Chevallier, Patrice, Saiagh, Soraya, Dehame, Virginie, Guillaume, Thierry, Peterlin, Pierre, Bercegeay, Sylvain, Le Bris, Yannick, Bossard, Céline, Gauvrit, Isabelle, Dreno, Brigitte, Juge-Morineau, Nadine, Béné, Marie C., Gregoire, Marc

“…This was a phase I/II study testing the feasibility of a vaccine by autologous leukemic apoptotic corpse-pulsed dendritic cells (DC) in elderly acute myeloid…”
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T-cell therapy using a bank of EBV-specific cytotoxic T cells: lessons from a phase I/II feasibility and safety study by Gallot, Géraldine, Vollant, Solène, Saïagh, Soraya, Clémenceau, Béatrice, Vivien, Régine, Cerato, Evelyne, Bignon, Jean-D, Ferrand, Christophe, Jaccard, Arnaud, Vigouroux, Stéphane, Choquet, Sylvain, Dalle, Jean-Hugues, Frachon, Irène, Bruno, Bénédicte, Mothy, Mohamad, Mechinaud, Françoise, Leblond, Véronique, Milpied, Noël, Vié, Henri

“…We report herein the results we obtained and the limitations we experienced during the production and use of a bank of Epstein-Barr virus (EBV)-transformed…”
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Treatment of Metastatic Melanoma with Autologous Melan-A/Mart-1-Specific Cytotoxic T Lymphocyte Clones by Khammari, Amir, Labarrière, Nathalie, Vignard, Virginie, Nguyen, Jean-Michel, Pandolfino, Marie-Christine, Knol, Anne C., Quéreux, Gaëlle, Saiagh, Soraya, Brocard, Anabelle, Jotereau, Francine, Dreno, Brigitte

“…Immunotherapy by adoptive T-cell transfer aims at maximizing tumor antigen-specific T-cell responses. We treated 14 patients at the metastatic stage in a phase…”
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The doubling potential of T lymphocytes allows clinical-grade production of a bank of genetically modified monoclonal T-cell populations by Vivien, Régine, Saïagh, Soraya, Lemarre, Philippe, Chabaud, Valérie, Jesson, Béline, Godon, Catherine, Jarry, Ulrich, Guillaume, Thierry, Chevallier, Patrice, Vié, Henri, Clémenceau, Béatrice

“…Abstract Background aims To produce an anti-leukemic effect after hematopoietic stem cell transplantation we have long considered the theoretical possibility…”
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Preclinical assessment of Autologous Tolerogenic Dendritic Cells from End-stage renal disease patients by Bouchet-Delbos, Laurence, Even, Amandine, Varey, Emilie, Saïagh, Soraya, Bercegeay, Sylvain, Braudeau, Cécile, Dréno, Brigitte, Blancho, Gilles, Josien, Régis, Cuturi, Maria-Cristina, Moreau, Aurélie

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Tissue biomarkers in melanoma patients treated with TIL by Knol, Anne-Chantal, Nguyen, Jean-Michel, Pandolfino, Marie-Christine, Quéreux, Gaëlle, Brocard, Anabelle, Peuvrel, Lucie, Saint-Jean, Mélanie, Saiagh, Soraya, Khammari, Amir, Dréno, Brigitte

“…While treating stage III melanoma patients with autologous therapeutic TIL in an adjuvant setting, we previously reported a significant benefit of treatment on…”
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Large scale expansion of gamma 9 delta 2 T lymphocytes: Innacell gamma delta cell therapy product by Salot, Samuel, Laplace, Catherine, Saïagh, Soraya, Bercegeay, Sylvain, Tenaud, Isabelle, Cassidanius, Alain, Romagne, François, Dreno, Brigitte, Tiollier, Jérôme

“…gamma9delta2 T lymphocytes are non-conventional lymphocytes presenting a direct cytotoxic effect against a broad range of tumour targets. These cells also…”
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New chondrosarcoma cell lines and mouse models to study the link between chondrogenesis and chemoresistance by Monderer, David, Luseau, Alexandrine, Bellec, Amélie, David, Emmanuelle, Ponsolle, Stéphanie, Saiagh, Soraya, Bercegeay, Sylvain, Piloquet, Philippe, Denis, Marc G, Lodé, Laurence, Rédini, Françoise, Biger, Marine, Heymann, Dominique, Heymann, Marie-Françoise, Le Bot, Ronan, Gouin, François, Blanchard, Frédéric

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Large scale expansion of Vγ9Vδ2 T lymphocytes from human peripheral blood mononuclear cells after a positive selection using MACS “TCR γ/δ + T cell isolation kit” by Salot, Samuel, Bercegeay, Sylvain, Dreno, Brigitte, Saïagh, Soraya, Scaglione, Virginie, Bonnafous, Cécile, Sicard, Hélène

“…Interest in γ9δ2 T cells has increased greatly in the past decade. While several protocols allowed the amplification of a large proportion of these cells in…”
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Large scale expansion of γ9δ2 T lymphocytes: Innacell γδ™ cell therapy product by Salot, Samuel, Laplace, Catherine, Saïagh, Soraya, Bercegeay, Sylvain, Tenaud, Isabelle, Cassidanius, Alain, Romagne, François, Dreno, Brigitte, Tiollier, Jérôme

“…γ9δ2 T lymphocytes are non-conventional lymphocytes presenting a direct cytotoxic effect against a broad range of tumour targets. These cells also secrete…”
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265.3: Advancing CD8+ Treg cell therapy to the clinic for the treatment of kidney transplanted patients by Bezie, Severine, Salle, Sonia, Lucazeau, Mariane, Saiagh, Soraya, Leveque, Marie-Christine, Braudeau, Cécile, Benjelloun Zahar, Mina, Vrignaud, Florence, Guillot-Gueguen, Cecile, Papuchon, Emmanuelle, Clémenceau, Béatrice, Ningre, Maëlle, Josien, Régis, Blancho, Gilles, Cantarovich, Diego, Anegon, Ignacio, Guillonneau, Carole

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