Search Results - "SZOLCSANYI, J"

Forty years in capsaicin research for sensory pharmacology and physiology by SZOLCSANYI, Janos

“…Capsaicin, the pungent ingredient of chilli peppers has become a “hot” topic in neuroscience with yearly publications over half thousand papers. It is outlined…”
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Sumatriptan causes parallel decrease in plasma calcitonin gene-related peptide (CGRP) concentration and migraine headache during nitroglycerin induced migraine attack by Juhasz, G, Zsombok, T, Jakab, B, Nemeth, J, Szolcsanyi, J, Bagdy, G

“…Sumatriptan-induced changes in plasma calcitonin gene-related peptide (CGRP) concentration and headache intensity were investigated in 19 female migraineurs…”
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Daily body temperature rhythm and heat tolerance in TRPV1 knockout and capsaicin pretreated mice by Szelényi, Z., Hummel, Z., Szolcsányi, J., Davis, J. B.

“…Daily body temperature (DBT) rhythm of mice lacking one of the transient receptor potential (TRP) family of proteins, the capsaicin receptor or TRPV1, was…”
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Capsaicin-sensitive sensory nerve terminals with local and systemic efferent functions: facts and scopes of an unorthodox neuroregulatory mechanism by Szolcsányi, J

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Are cannabinoids endogenous ligands for the VR1 capsaicin receptor? by Szolcsányi, J

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Anandamide and the question of its functional role for activation of capsaicin receptors by Szolcsányi, János

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Sensory neuron-specific actions of capsaicin: mechanisms and applications by Bevan, S, Szolcsányi, J

“…Capsaicin acts specifically on a subset of primary afferent sensory neurons to open cation-selective ion channels, probably by interacting directly with a…”
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Neonatal capsaicin treatment results in prolonged mitochondrial damage and delayed cell death of B cells in the rat trigeminal ganglia by Szöke, É, Seress, L, Szolcsányi, J

“…Capsaicin acts on the vanilloid receptor subtype 1, a noxious heat-gated cation channel located on a major subgroup of nociceptive primary afferent neurons…”
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Release of somatostatin and its role in the mediation of the anti‐inflammatory effect induced by antidromic stimulation of sensory fibres of rat sciatic nerve by Szolcsányi, János, Helyes, Zsuzsanna, Oroszi, Gábor, Németh, József, Pintér, Erika

“…1 The effect of antidromic stimulation of the sensory fibres of the sciatic nerve on inflammatory plasma extravasation in various tissues and on cutaneous…”
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Hot target on nociceptors: perspectives, caveats and unique features by Szolcsanyi, J

“…Identification of C‐polymodal nociceptors and the selective action of capsaicin on them by acting on a putative receptor, which has been cloned 11 years ago,…”
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Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals by Helyes, Zsuzsanna, Németh, József, Pintér, Erika, Szolcsányi, János

“…Pretreatment with the novel neuropeptide nociceptin (20 μg kg−1, i.p.) caused an inhibition of plasma extravasation evoked by antidromic stimulation of the…”
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Chronic stress‐induced mechanical hyperalgesia is controlled by capsaicin‐sensitive neurones in the mouse by Scheich, B., Vincze, P., Szőke, É., Borbély, É., Hunyady, Á., Szolcsányi, J., Dénes, Á., Környei, Zs, Gaszner, B., Helyes, Zs

“…Background Clinical studies demonstrated peripheral nociceptor deficit in stress‐related chronic pain states, such as fibromyalgia. The interactions of stress…”
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Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat by Helyes, Zsuzsanna, Németh, József, Thán, Márta, Bölcskei, Kata, Pintér, Erika, Szolcsányi, János

“…Anandamide (AEA) is an endogenous cannabinoid ligand acting predominantly on the cannabinoid 1 (CB 1) receptor, but it is also an agonist on the capsaicin VR…”
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Plasma extravasation in the skin and pelvic organs evoked by antidromic stimulation of the lumbosacral dorsal roots of the rat by PINTER, E, SZOLCSANYI, J

“…Electrical stimulation of the distal stump of cut peripheral nerves is a commonly accepted way to evoke neurogenic inflammation. Nevertheless, the modulatory…”
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Anti‐inflammatory effect of synthetic somatostatin analogues in the rat by Helyes, Zsuzsanna, Pintér, Erika, Németh, József, Kéri, György, Thán, Márta, Oroszi, Gábor, Horváth, Anikó, Szolcsányi, János

“…Somatostatin (6.11 nmol kg−1 i.p.) inhibited neurogenic plasma extravasation evoked by 1% mustard oil and non‐neurogenic oedema induced by 5% dextran in the…”
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Four response stages of capsaicin-sensitive primary afferent neurons to capsaicin and its analog: Gastric acid secretion, gastric mucosal damage and protection by MOZSIK, Gyula, VINCZE, Aron, SZOLCSANYI, Janos

“…Capsaicin is the active component of red hot peppers, which modifies specifically the capsaicin‐sensitive sensory afferent nerves. The action of capsaicin is…”
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Alterations in mucosal neuropeptides in patients with irritable bowel syndrome and ulcerative colitis in remission: A role in pain symptom generation? by Keszthelyi, D., Troost, F.J., Jonkers, D.M., Helyes, Z., Hamer, H.M., Ludidi, S., Vanhoutvin, S., Venema, K., Dekker, J., Szolcsányi, J., Masclee, A.A.

“…Background Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by chronic abdominal pain. The transient receptor potential…”
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Systemic anti‐inflammatory effect induced by counter‐irritation through a local release of somatostatin from nociceptors by Szolcsányi, János, Pintér, Erika, Helyes, Zsuzsanna, Oroszi, Gábor, Németh, József

“…1 Neurogenic plasma extravasation evoked by topical application of 1% vv−1 mustard oil on the skin of the acutely denervated rat hindleg (primary reaction)…”
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Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig by Thán, Márta, Németh, József, Szilvássy, Zoltán, Pintér, Erika, Helyes, Zsuzsanna, Szolcsányi, János

“…The systemic anti-inflammatory effect induced by antidromic sensory nerve stimulation was investigated in rats and guinea-pigs. In atropine-pretreated rats,…”
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Anti-nociceptive effect induced by somatostatin released from sensory nerve terminals and by synthetic somatostatin analogues in the rat by Helyes, Zsuzsanna, Thán, Márta, Oroszi, Gábor, Pintér, Erika, Németh, József, Kéri, György, Szolcsányi, János

“…In rats anaesthetized with urethan and pretreated with pipecuronium bromide nocifensive reaction of blood pressure elevation evoked by intraarterial capsaicin…”
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