Search Results - "SZEMRAJ, Zofia"
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Circulating microRNAs as biomarkers for myocardial fibrosis in patients with left ventricular non-compaction cardiomyopathy
Published in Archives of medical science (01-03-2019)“…Despite the fact that cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) is a proven method for detecting myocardial fibrosis,…”
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CD38 Gene Polymorphisms Contribute to Genetic Susceptibility to B-Cell Chronic Lymphocytic Leukemia: Evidence from Two Case-Control Studies in Polish Caucasians
Published in Cancer epidemiology, biomarkers & prevention (01-03-2009)“…Given the recent findings on the importance of CD38 signaling in the pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL), we hypothesized that single…”
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3
Impact of polymorphic variation at 7p15.3, 3p22.1 and 2p23.3 loci on risk of multiple myeloma
Published in British journal of haematology (01-09-2012)Get full text
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4
Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk
Published in British journal of haematology (01-07-2011)“…Summary A genome‐wide association study of chronic lymphocytic leukaemia (CLL) suggested that common variants at 15q25.2 (rs783540) and 18q21.1 (rs1036935)…”
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Comprehensive investigation of genetic variation in the 8q24 region and multiple myeloma risk in the IMMEnSE consortium
Published in British journal of haematology (01-05-2012)“…Genome‐wide association studies (GWAS) have shown that the 8q24 region harbours multiple independent cancer susceptibility loci, even though it is devoid of…”
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6
Clinical Relevance of Vascular Endothelial Growth Factor Type A (VEGFA) and VEGF Receptor Type 2 (VEGFR2) Gene Polymorphism In Chronic Lymphocytic Leukemia
Published in Blood (19-11-2010)“…Abstract 4467 Vascular endothelial growth factor type A (VEGFA) is a key regulator of angiogenesis and vascular permeability. Given that chronic lymphocytic…”
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Cloning and expression of a new recombinant thrombolytic and anthithrombotic agent - a staphylokinase variant
Published in Acta biochimica polonica (2009)“…To develop a more potent antithrombin agent with thrombolytic and antiplatelet properties, a new staphylokinase (SAK) variant was constructed. The kringle 2…”
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Polymorphisms in CD31/PECAM-1 and CD38 Genes Are Associated with Susceptibility to Multiple Myeloma
Published in Blood (16-11-2008)“…Interactions with bone marrow microenvironment play a major role in the control of multiple myeloma (MM) growth and survival. MM clonal plasma cells co-express…”
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9
CD38 Gene Polymorphisms Contribute to Genetic Predisposition to B-Cell Chronic Lymphocytic Leukemia
Published in Blood (16-11-2007)“…Genetic background and abnormal immune response are supposed to play a role in the pathogenesis of B-cell chronic lymphocytic leukaemia (B-CLL). CD38 is a…”
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10
The level of origin of renal arteries in horseshoe kidney vs. in separated kidneys: CT-based study
Published in Surgical and radiologic anatomy (English ed.) (01-10-2018)“…Purpose Horseshoe kidney is a rare congenital anomaly with potential clinical implications. The aim of this study was to determine the number of renal arteries…”
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11
Pharmacogenetics of Response to Glucocorticosteroids in Adults with Acute Lymphoblastic Leukemia
Published in Blood (16-11-2006)“…Glucocorticoids are crucial components of standard chemotherapy regimens used for the treatment of adult acute lymphoblastic leukemia (ALL). However, little is…”
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12
Does the type of renal artery anatomic variant determine the diameter of the main vessel supplying a kidney? A study based on CT data with a particular focus on the presence of multiple renal arteries
Published in Surgical and radiologic anatomy (English ed.) (01-04-2018)“…Background An in-depth knowledge of renal vascular anatomy is essential when planning many surgical procedures; however, a few data exists regarding renal…”
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13
Cloning and expression of a new recombinant thrombolytic and anthithrombotic agent - a staphylokinase variant
Published in Acta biochimica polonica (19-11-2008)“…To develop a more potent antithrombin agent with thrombolytic and antiplatelet properties, a new staphylokinase (SAK) variant was constructed. The kringle 2…”
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14
Genetics and molecular epidemiology of multiple myeloma: The rationale for the IMMEnSE consortium (Review)
Published in International journal of oncology (01-03-2012)“…There is strong evidence suggesting the presence of a genetic component in the aetiology of multiple myeloma (MM). However no genetic risk factors have been…”
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15
Type 2 Diabetes-Related Variants Influence on the Risk of Developing Multiple Myeloma: Results from the Immense Consortium
Published in Blood (06-12-2014)“…Type 2-diabetes (T2D) is thought to be a relevant risk factor for multiple myeloma (MM), but the relationship between both traits is still not well understood…”
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The International Multiple Myeloma Research (IMMEnSE) Consortium: Genetics of Multiple Myeloma Risk and Prognosis
Published in Blood (06-12-2014)“…We established the IMMEnSE (International Multiple Myeloma rESEarch) consortium, to increase our understanding of the genetic determinants of multiple myeloma…”
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Polymorphisms of Mir-34b/c, Mir-146a and Mir-196a-2 and Predisposition to Chronic Lymphocytic Leukemia and Monoclonal B-Cell Lymphocytosis
Published in Blood (18-11-2011)“…Abstract 4585 Since microRNAs control expression of protein-coding oncogenes and tumor suppressor genes, functional microRNAs single nucleotide polymorphisms…”
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Comprehensive investigation of genetic variation in the 8q24 region and multiple myeloma risk in the IMME n SE consortium
Published in British journal of haematology (01-05-2012)“…Genome‐wide association studies ( GWAS ) have shown that the 8q24 region harbours multiple independent cancer susceptibility loci, even though it is devoid of…”
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19
Polymorphisms in Regulators of Xenobiotic Transport and Metabolism Genes NR1I2 and NR1I3 and Multiple Myeloma Risk: A Case-Control Study in the Context of IMMEnSE Consortium
Published in Blood (18-11-2011)“…Abstract 5014 Exposure to toxic compounds and pesticides leads to an increased risk to develop Multiple Myeloma (MM). The metabolism and the excretion of…”
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20
CD38 gene polymorphisms and genetic predisposition to multiple myeloma
Published in Acta haematologica polonica (01-01-2013)“…Single nucleotide polymorphisms (SNPs) of adhesion and signaling genes may influence the etiopathogenesis of multiple myeloma (MM). CD38 molecule and its…”
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