Search Results - "SZE HUEY TAN"
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Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Trials
Published in Clinical cancer research (15-04-2018)“…Because of the uneven geographic distribution and small number of randomized trials available, the value of additional induction chemotherapy (IC) to…”
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Concurrent Chemo-Radiation With or Without Induction Gemcitabine, Carboplatin, and Paclitaxel: A Randomized, Phase 2/3 Trial in Locally Advanced Nasopharyngeal Carcinoma
Published in International journal of radiation oncology, biology, physics (01-04-2015)“…Purpose To compare survival, tumor control, toxicities, and quality of life of patients with locally advanced nasopharyngeal carcinoma (NPC) treated with…”
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3
Sensor performance and computational study of polyaniline film in ethylenediamine detection
Published in Polymer engineering and science (01-01-2024)“…The incorporation of computational chemistry toward the assessment of polyaniline (PAni) performance as ethylenediamine (EDA) sensor is first explored in this…”
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4
Clinical efficacy and biomarker analysis of dual PD-1/CTLA-4 blockade in recurrent/metastatic EBV-associated nasopharyngeal carcinoma
Published in Nature communications (15-05-2023)“…Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased…”
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The treatment landscape of advanced angiosarcoma in Asia—A multi‐national collaboration from the Asian Sarcoma Consortium
Published in Cancer science (01-03-2021)“…Angiosarcoma (AS) is a rare disease with a dismal prognosis. The treatment landscape and prognostic factors for advanced AS, including locally advanced,…”
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Early recurrence after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)
Published in International journal of clinical oncology (01-10-2018)“…Background Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are used in the management of selected peritoneal malignancies…”
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Development of a risk classification system combining TN-categories and circulating EBV DNA for non-metastatic NPC in 10,149 endemic cases
Published in Therapeutic advances in medical oncology (2021)“…Background: The objective of this study was to construct a risk classification system integrating cell-free Epstein-Barr virus (cfEBV) DNA with T- and N-…”
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The Correct Interpretation of Confidence Intervals
Published in Proceedings of Singapore healthcare (01-09-2010)Get full text
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Adoptive T-cell Transfer and Chemotherapy in the First-line Treatment of Metastatic and/or Locally Recurrent Nasopharyngeal Carcinoma
Published in Molecular therapy (01-01-2014)“…The outcomes for patients with metastatic or locally recurrent Epstein–Barr virus (EBV)-positive nasopharyngeal carcinoma (NPC) remain poor. Adoptive…”
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Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer
Published in Journal of clinical oncology (10-04-2019)“…Mesenchymal epithelial transition factor ( MET) activation has been implicated as an oncogenic driver in epidermal growth factor receptor ( EGFR)-mutant…”
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Exploring MRI based radiomics analysis of intratumoral spatial heterogeneity in locally advanced nasopharyngeal carcinoma treated with intensity modulated radiotherapy
Published in PloS one (05-10-2020)“…Background We hypothesized that spatial heterogeneity exists between recurrent and non-recurrent regions within a tumor. The aim of this study was to determine…”
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Intrinsic Subtypes of Gastric Cancer, Based on Gene Expression Pattern, Predict Survival and Respond Differently to Chemotherapy
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2011)“…Background & Aims Gastric cancer (GC) is a heterogeneous disease comprising multiple subtypes that have distinct biological properties and effects in patients…”
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13
Impact of cancer diagnoses on the outcomes of patients with COVID-19: a systematic review and meta-analysis
Published in BMJ open (07-02-2022)“…BackgroundThe COVID-19 has caused significant mortality and morbidity across the globe. Patients with cancer are especially vulnerable given their…”
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Use of calcium and magnesium infusions in prevention of oxaliplatin induced sensory neuropathy
Published in Asia-Pacific journal of clinical oncology (01-12-2010)“…Aim: Oxaliplatin‐related neurotoxicity is frequently dose‐limiting. Following retrospective studies suggesting neuroprotective effects of calcium and…”
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15
Association of clinical factors with survival outcomes in laryngeal squamous cell carcinoma (LSCC)
Published in PloS one (20-11-2019)“…Treatment strategies in laryngeal squamous cell cancer (LSCC) straddle the need for long term survival and tumor control as well as preservation of laryngeal…”
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16
Upregulated mRNA expression of desaturase and elongase, two enzymes involved in highly unsaturated fatty acids biosynthesis pathways during follicle maturation in zebrafish
Published in Reproductive biology and endocrinology (24-11-2008)“…Although unsaturated fatty acids such as eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (ARA, C20:4n-6),…”
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Bayesian Multiparameter Evidence Synthesis to Inform Decision Making: A Case Study in Metastatic Hormone-Refractory Prostate Cancer
Published in Medical decision making (01-10-2018)“…In health technology assessment, decisions are based on complex cost-effectiveness models that require numerous input parameters. When not all relevant…”
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Understanding the Psychological Impact of COVID-19 Pandemic on Patients With Cancer, Their Caregivers, and Health Care Workers in Singapore
Published in JCO global oncology (01-10-2020)“…The coronavirus disease 2019 (COVID-19) pandemic has had a global impact, and Singapore has seen 33,000 confirmed cases. Patients with cancer, their…”
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A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma
Published in Nature communications (28-10-2022)“…Cancer vaccines as immunotherapy for solid tumours are currently in development with promising results. We report a phase 1 study of Ad-sig-hMUC1/ecdCD40L…”
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Evaluation of the PIK3 pathway in peripheral T‐cell lymphoma and NK/T‐cell lymphoma
Published in British journal of haematology (01-05-2020)“…Summary Peripheral T‐cell lymphomas (PTCL) and natural killer (NK)/T‐cell lymphomas (NKTCL) are a heterogeneous group of aggressive malignancies with dismal…”
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