Search Results - "SZATMARI, Erzsebet"

CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca2+ Signals during LTP Induction, but Not Maintenance by Chang, Jui-Yun, Parra-Bueno, Paula, Laviv, Tal, Szatmari, Erzsebet M., Lee, Seok-Jin R., Yasuda, Ryohei

“…CaMKII plays a critical role in decoding calcium (Ca2+) signals to initiate long-lasting synaptic plasticity. However, the properties of CaMKII that mediate…”
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Activation of CaMKII in single dendritic spines during long-term potentiation by Lee, Seok-Jin R., Escobedo-Lozoya, Yasmin, Szatmari, Erzsebet M., Yasuda, Ryohei

“…Calcium/calmodulin-dependent kinase II (CaMKII) plays a central part in long-term potentiation (LTP), which underlies some forms of learning and memory. Here…”
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AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK–dependent manner during long-term potentiation by Patterson, Michael A., Szatmari, Erzsebet M., Yasuda, Ryohei, Huganir, Richard L.

“…The exocytosis of AMPA receptors is a key step in long-term potentiation (LTP), yet the timing and location of exocytosis and the signaling pathways involved…”
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Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor by Murakoshi, Hideji, Shin, Myung Eun, Parra-Bueno, Paula, Szatmari, Erzsebet M., Shibata, Akihiro C.E., Yasuda, Ryohei

“…Elucidating temporal windows of signaling activity required for synaptic and behavioral plasticity is crucial for understanding molecular mechanisms underlying…”
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CRY–BARs: Versatile light-gated molecular tools for the remodeling of membrane architectures by Wurz, Anna I., Bunner, Wyatt P., Szatmari, Erzsebet M., Hughes, Robert M.

“…BAR (Bin, Amphiphysin, and Rvs) protein domains are responsible for the generation of membrane curvature and represent a critical mechanical component of…”
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Crosstalk between the Rho and Rab family of small GTPases in neurodegenerative disorders by Nik Akhtar, Shayan, Bunner, Wyatt P, Brennan, Elizabeth, Lu, Qun, Szatmari, Erzsebet M

“…Neurodegeneration is associated with defects in cytoskeletal dynamics and dysfunctions of the vesicular trafficking and sorting systems. In the last few…”
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CRY‐BAR: A versatile light‐gated tool for the remodeling of membrane architectures by Wurz, Anna I., Bunner, Wyatt P., Szatmari, Erzsebet M., Hughes, Robert M.

“…BAR (Bin, Amphiphysin and Rvs) protein domains are responsible for the generation of membrane curvature and represent a critical mechanical component of…”
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Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor by Murakoshi, Hideji, Shin, Myung Eun, Parra-Bueno, Paula, Szatmari, Erzsebet M., Shibata, Akihiro C.E., Yasuda, Ryohei

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Transfection and Activation of CofActor, a Light and Stress Gated Optogenetic Tool, in Primary Hippocampal Neuron Cultures by Bunner, Wyatt P, Dodson, Rachel, Hughes, Robert M, Szatmari, Erzsebet M

“…Proteins involved in neurodegeneration can be coupled with optogenetic reagents to create rapid and sensitive reporters to provide insight into the biochemical…”
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CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells by Salem, Fatema B., Bunner, Wyatt P., Prabhu, Vishwanath V., Kuyateh, Abu-Bakarr, O'Bryant, Collin T., Murashov, Alexander K., Szatmari, Erzsebet M., Hughes, Robert M.

“…The hallmarks of neurodegenerative diseases, including neural fibrils, reactive oxygen species, and cofilin–actin rods, present numerous challenges in the…”
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Centaurin- alpha 1-Ras-Elk-1 Signaling at Mitochondria Mediates beta -Amyloid-Induced Synaptic Dysfunction by Szatmari, Erzsebet M, Oliveira, Ana F, Sumner, Elizabeth J, Yasuda, Ryohei

“…Alzheimer's disease is thought to be caused by beta -amyloid peptide (A beta )-dependent synaptic dysfunction. However, the signaling pathways connecting A…”
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CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca 2+ Signals during LTP Induction, but Not Maintenance by Chang, Jui-Yun, Parra-Bueno, Paula, Laviv, Tal, Szatmari, Erzsebet M, Lee, Seok-Jin R, Yasuda, Ryohei

“…CaMKII plays a critical role in decoding calcium (Ca ) signals to initiate long-lasting synaptic plasticity. However, the properties of CaMKII that mediate Ca…”
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Centaurin-α1-Ras-Elk-1 signaling at mitochondria mediates β-amyloid-induced synaptic dysfunction by Szatmari, Erzsebet M, Oliveira, Ana F, Sumner, Elizabeth J, Yasuda, Ryohei

“…Alzheimer's disease is thought to be caused by β-amyloid peptide (Aβ)-dependent synaptic dysfunction. However, the signaling pathways connecting Aβ and…”
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Behavioral and Transcriptome Profiling of Heterozygous Rab10 Knock-Out Mice by Bunner, Wyatt, Wang, Jie, Cohen, Sarah, Bashtovyy, Denys, Perry, Rachel, Shookster, Daniel, Landry, Taylor, Harris, Elizabeth M, Stackman, Robert, Tran, Tuan D, Yasuda, Ryohei, Szatmari, Erzsebet M

“…A central question in the field of aging research is to identify the cellular and molecular basis of neuroresilience. One potential candidate is the small…”
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ADAP1/Centaurin-α1 Negatively Regulates Dendritic Spine Function and Memory Formation in the Hippocampus by Szatmari, Erzsebet M, Moran, Corey, Cohen, Sarah, Jacob, Amanda, Parra-Bueno, Paula, Kamasawa, Naomi, Guerrero-Given, Debbie, Klein, Michael, Stackman, Jr, Robert, Yasuda, Ryohei

“…ADAP1/Centaurin-α1 (CentA1) functions as an Arf6 GTPase-activating protein highly enriched in the brain. Previous studies demonstrated the involvement of…”
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Role of Kinase Suppressor of Ras-1 in Neuronal Survival Signaling by Extracellular Signal-Regulated Kinase 1/2 by Szatmari, Erzsebet, Kalita, Katarzyna B, Kharebava, Giorgi, Hetman, Michal

“…Scaffolding proteins including kinase suppressor of Ras-1 (KSR1) determine specificity of signaling by extracellular signal-regulated kinase 1/2 (ERK1/2),…”
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Mechanisms of ammonia-induced cell death in rat cortical neurons: Roles of NMDA receptors and glutathione by Klejman, Agata, Węgrzynowicz, Michał, Szatmari, Erzsebet M., Mioduszewska, Barbara, Hetman, Michał, Albrecht, Jan

“…The occurrence, nature and prevention of ammonia-induced cell death were assayed in cultured primary cortical neurons from newborn rats. Treatment with 1–10 mM…”
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Prenatal and postnatal genetic testing toward personalized care: The non-invasive perinatal testing by Botos, Lilla, Szatmári, Erzsébet, Nagy, Gyula Richárd

“…This article investigates how non-invasive prenatal testing and the incorporation of genomic sequencing into newborn screening postnatally are transforming…”
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NMDA neuroprotection against a phosphatidylinositol‐3 kinase inhibitor, LY294002 by NR2B‐mediated suppression of glycogen synthase kinase‐3β‐induced apoptosis by Habas, Agata, Kharebava, Giorgi, Szatmari, Erzsebet, Hetman, Michal

“…To identify the intracellular signaling pathways that mediate the pro‐survival activity of NMDA receptors (NMDARs), we studied effects of exogenous NMDA on…”
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A Positive Feedback Loop between Glycogen Synthase Kinase 3β and Protein Phosphatase 1 after Stimulation of NR2B NMDA Receptors in Forebrain Neurons by Szatmari, Erzsebet, Habas, Agata, Yang, Peng, Zheng, Jing-Juan, Hagg, Theo, Hetman, Michal

“…N-methyl-d-aspartate receptors (NMDARs) are critical for neuronal plasticity and survival, whereas their excessive activation produces excitotoxicity and may…”
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