Search Results - "SZABADOS, E"

Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease by Magyar, K, Halmosi, R, Palfi, A, Feher, G, Czopf, L, Fulop, A, Battyany, I, Sumegi, B, Toth, K, Szabados, E

“…Several beneficial effects of resveratrol (RES), a natural antioxidant present in red wine have already been described. The aim of our study was to investigate…”
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Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer by Rijnders, Maud, Nakauma-González, J. Alberto, Robbrecht, Debbie G. J., Gil-Jimenez, Alberto, Balcioglu, Hayri E., Oostvogels, Astrid A. M., Aarts, Maureen J. B., Boormans, Joost L., Hamberg, Paul, van der Heijden, Michiel S., Szabados, Bernadett E., van Leenders, Geert J. L. H., Mehra, Niven, Voortman, Jens, Westgeest, Hans M., de Wit, Ronald, van der Veldt, Astrid A. M., Debets, Reno, Lolkema, Martijn P.

“…Immune checkpoint inhibitors (ICI) improve overall survival in patients with metastatic urothelial cancer (mUC), but therapeutic success at the individual…”
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ctDNA guiding adjuvant immunotherapy in urothelial carcinoma by Powles, Thomas, Assaf, Zoe June, Davarpanah, Nicole, Banchereau, Romain, Szabados, Bernadett E., Yuen, Kobe C., Grivas, Petros, Hussain, Maha, Oudard, Stephane, Gschwend, Jürgen E., Albers, Peter, Castellano, Daniel, Nishiyama, Hiroyuki, Daneshmand, Siamak, Sharma, Shruti, Zimmermann, Bernhard G., Sethi, Himanshu, Aleshin, Alexey, Perdicchio, Maurizio, Zhang, Jingbin, Shames, David S., Degaonkar, Viraj, Shen, Xiaodong, Carter, Corey, Bais, Carlos, Bellmunt, Joaquim, Mariathasan, Sanjeev

“…Minimally invasive approaches to detect residual disease after surgery are needed to identify patients with cancer who are at risk for metastatic relapse…”
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CABOSEQ: The Effectiveness of Cabozantinib in Patients With Treatment Refractory Advanced Renal Cell Carcinoma: Results From the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) by Navani, Vishal, Wells, J Connor, Boyne, Devon J, Cheung, Winson Y, Brenner, Darren M, McGregor, Bradley A, Labaki, Chris, Schmidt, Andrew L, McKay, Rana R, Meza, Luis, Pal, Sumanta K, Donskov, Frede, Beuselinck, Benoit, Otiato, Maxwell, Ludwig, Lisa, Powles, Thomas, Szabados, Bernadett E, Choueiri, Toni K, Heng, Daniel Y C

“…•There is clinically meaningful activity of second Line cabo post contemporary first line options.•Time to event endpoints are similar irrespective of first…”
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Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography by Szabados, E, Christopherson, R I

“…A radioassay has been developed for the bifunctional enzyme, AICAR transformylase-IMP cyclohydrolase, which catalyzes reactions 9 and 10 of the de novo pathway…”
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Metabolism of adenosine and deoxyadenosine by human erythrocytes and CCRF-CEM leukemia cells by Szabados, Eve, Duggleby, Ronald G., Christopherson, Richard I.

“…Human lymphocytes lacking adenosine deaminase die and T-cell leukemias are killed by deoxycoformycin (dCf), an inhibitor of adenosine deaminase, due to…”
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PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats by Bartha, Eva, Solti, Izabella, Kereskai, Laszlo, Lantos, Janos, Plozer, Eniko, Magyar, Klara, Szabados, Eszter, Kálai, Tamás, Hideg, Kálmán, Halmosi, Robert, Sumegi, Balazs, Toth, Kalman

“…Aims Oxidative stress followed by abnormal signalling can play a critical role in the development of long-term, high blood pressure-induced cardiac remodelling…”
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Inhibitors of dihydro-orotase, amidophosphoribosyltransferase and IMP cyclohydrolase as potential drugs by Christopherson, R I, Williams, N K, Schoettle, S L, Szabados, E, Hambley, T W, Manthey, M K

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BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymerase by Szabados, Eszter, Literati-Nagy, Peter, Farkas, Beatrix, Sumegi, Balazs

“…The protective effect of O-(3-piperidino-2-hydroxy-1-propyl)nicotinic amidoxime (BGP-15) against ischemia–reperfusion-induced injury was studied in the…”
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Peripheral B-lymphocyte markers and function in IgA nephropathy by Magyarlaki, T, Davin, J C, Szabados, E, Kocsis, B, Nagy, J

“…Peripheral blood B-lymphocyte markers and functions were observed in 21 patients with IgA nephropathy (IgA NP) and in 16 controls. IgA NP B lymphocytes…”
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The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts by Pálfi, Anita, Tóth, Ambrus, Kulcsár, Gyozo, Hantó, Katalin, Deres, Péter, Bartha, Eva, Halmosi, Róbert, Szabados, Eszter, Czopf, László, Kálai, Tamás, Hideg, Kálmán, Sümegi, Balázs, Tóth, Kálmán

“…Blocking poly(ADP-ribosyl)ation of nuclear proteins protects the heart from ischemia-reperfusion injury. In addition, activation of Akt and mitogen-activated…”
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Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat by Szabados, Eszter, Fischer, GaborM, Toth, Kalman, Csete, Bela, Nemeti, Balazs, Trombitas, Karoly, Habon, Tamas, Endrei, Dora, Sumegi, Balazs

“…The short term cardiac side-effects of AZT (3′-azido-3′-deoxythymidine, zidovudine) was studied in rats to understand the biochemical events contributing to…”
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Inhibition of Amido Phosphoribosyltransferase by Antifolates in Mouse L1210 Leukaemia Cells by Sant M. E., Lyons S. D., Phillips L., Szabados E., Christopherson R. I.

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Effect of transtympanally applied lidocaine on the cochleovestibular function by Szabados, E, Nagymajtényi, E, Ribári, O, Boda, K

“…Twenty-two patients with recurring attacks of tinnitus, hearing loss and dizziness were treated with transtympanally injected lidocaine. The tinnitus improved…”
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Nasal sarcoidosis--a review and a case report by Szabados, E, Kocsis, J, Karácsonyi, M, Nagymajtényi, E, Ribári, O

“…The literature relating to the diagnostics and therapy of Boeck's sarcoidosis is reviewed. A patient with sarcoidotic alteration of the nasal mucosa is…”
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Childhood rhabdomyosarcoma in otorhinolaryngology by Szabados, E, Ribári, O, Jóri, J, Illyés, M, Bohus, K

“…Two cases of childhood rhabdomyosarcoma with otorhinolaryngological localization are reported and the literature of this rare malignancy is reviewed. The…”
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The effect of carvedilol on enhanced ADP-ribosylation and red blood cell membrane damage caused by free radicals by HABON, Tamas, SZABADOS, Eszter, KESMARKY, Gabor, HALMOSI, Robert, PAST, Tibor, SUMEGI, Balazs, TOTH, Kalman

“…Previous studies have reported that the beta and alpha adrenoceptor blocker carvedilol has unique protective effects on free radical-induced myocardial injury…”
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Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart by Szabados, Eszter, Fischer, Gabor M, Gallyas, Ferenc, Kispal, Gyula, Sumegi, Balazs

“…Poly-ADP-ribose polymerase (PARP) is considered to play an important role in oxidative cell damage. We assumed that ischemia-reperfusion resulting from the…”
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Lyme Disease Associated With Postganglionic Horner Syndrome and Raeder Paratrigeminal Neuralgia by Murphy, Marjorie A, Szabados, Erica M, Mitty, Jennifer A

“…A 55-year-old woman developed severe unilateral headaches, periocular numbness, and Horner syndrome after presenting with symptoms consistent with Lyme…”
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Purine deoxynucleoside metabolism in human melanoma cells with a high spontaneous mutation rate by Musk, P, Clark, J M, Thompson, D, Dunn, I S, Christopherson, R I, Szabados, E, Rose, S E, Parsons, P G

“…A human melanoma cell line (MM96L) had a spontaneous mutation rate at the HGPRT locus of approx. 7 times normal. The cells had elevated dATP and dGTP pools,…”
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