Search Results - "SYRIGOS, Kostas"

The Biological Role of PI3K Pathway in Lung Cancer by Sarris, Evangelos G, Saif, Muhammad W, Syrigos, Kostas N

“…Lung cancer is the primary cause of cancer-related mortality worldwide and although improvements in treatment have been achieved over the last few years,…”
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The safety and efficacy of Onivyde (irinotecan liposome injection) for the treatment of metastatic pancreatic cancer following gemcitabine-based therapy by Passero, Frank C., Grapsa, Dimitra, Syrigos, Kostas N., Saif, Muhammad Wasif

“…Introduction: Patients with advanced and metastatic pancreatic cancer refractory to gemcitabine based therapy have a dismal prognosis and limited therapeutic…”
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Disparities in colorectal cancer in African-Americans vs Whites： Before and after diagnosis by Dimou, Anastasios, Syrigos, Kostas N, Saif, Muhammad Wasif

“…There are differences between African-American and white patients with colorectal cancer, concerning their characteristics before and after diagnosis. Whites…”
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The Potential of Combined Immunotherapy and Antiangiogenesis for the Synergistic Treatment of Advanced NSCLC by Manegold, Christian, Dingemans, Anne-Marie C, Gray, Jhanelle E, Nakagawa, Kazuhiko, Nicolson, Marianne, Peters, Solange, Reck, Martin, Wu, Yi-Long, Brustugun, Odd Terje, Crinò, Lucio, Felip, Enriqueta, Fennell, Dean, Garrido, Pilar, Huber, Rudolf M, Marabelle, Aurélien, Moniuszko, Marcin, Mornex, Françoise, Novello, Silvia, Papotti, Mauro, Pérol, Maurice, Smit, Egbert F, Syrigos, Kostas, van Meerbeeck, Jan P, van Zandwijk, Nico, Yang, James Chih-Hsin, Zhou, Caicun, Vokes, Everett

“…Over the past few years, there have been considerable advances in the treatments available to patients with metastatic or locally advanced NSCLC, particularly…”
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Sunitinib: A Multitargeted Receptor Tyrosine Kinase Inhibitor in the Era of Molecular Cancer Therapies by Papaetis, Georgios S., Syrigos, Kostas N.

“…Sunitinib is an oral oxindole multitargeted kinase inhibitor that inhibits certain receptor tyrosine kinases (RTKs). These include vascular endothelial growth…”
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Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Gemcitabine/Cisplatin Alone or With Sorafenib for the First-Line Treatment of Advanced, Nonsquamous Non–Small-Cell Lung Cancer by PAZ-ARES, Luis G, BIESMA, Bonne, SYRIGOS, Kostas, LE MARIE, Etienne, GOTTFRIED, Maya, VANSTEENKISTE, Johan, ALBEROLA, Vincente, PHILLIP STRAUSS, Uwe, MONTEGRIFFO, Elaine, JIN ONG, Teng, SANTORO, Armando, HEIGENER, David, VON PAWEL, Joachim, EISEN, Timothy, BENNOUNA, Jaafar, LI ZHANG, MEILIN LIAO, YAN SUN, GANS, Steven

“…This trial evaluated the efficacy and safety of sorafenib plus gemcitabine/cisplatin in chemotherapy-naive patients with unresectable stage IIIB to IV…”
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The role of mTOR in the management of solid tumors: An overview by Strimpakos, Alex S, Karapanagiotou, Eleni M, Saif, M. Wasif, Syrigos, Kostas N

“…Summary Mammalian target of rapamycin (mTOR) is a key protein kinase controlling signal transduction from various growth factors and upstream proteins to the…”
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Bevacizumab-Induced Hypertension: Pathogenesis and Management by Syrigos, Kostas N., Karapanagiotou, Eleni, Boura, Paraskevi, Manegold, Christian, Harrington, Kevin

“…Bevacizumab, a recombinant humanized monoclonal antibody targeting the vascular endothelial growth factor (VEGF), has been approved in the US as first- and…”
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Pancreatic cancer: from molecular pathogenesis to targeted therapy by Strimpakos, Alexios, Saif, Muhammad W., Syrigos, Kostas N.

“…Pancreatic cancer is a deadly malignancy with still high mortality and poor survival despite the significant advances in understanding, diagnosis, and access…”
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Chemotherapy-induced neutropenia in lung cancer patients: The role of antibiotic prophylaxis by Kouranos, Vasileios, Dimopoulos, George, Vassias, Antonios, Syrigos, Kostas N

“…Highlights ► We performed a PubMed literature search of manuscripts published until May 2011. ► Quinolones and trimethoprim/sulfamethoxazole were most…”
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Targeted therapeutic approaches for hormone-refractory prostate cancer by Stavridi, Flora, Karapanagiotou, Eleni M, Syrigos, Kostas N

“…Summary Prostate cancer is one of the leading causes of cancer related death in men, and remains incurable in the metastatic setting. Despite the initial…”
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S-1: a promising new oral fluoropyrimidine derivative by Saif, Muhammad Wasif, Syrigos, Kostas N, Katirtzoglou, Nikos A

“…S-1 is an oral fluoropyrimidine that is designed to improve the antitumor activity of 5-fluorouracil (5-FU) concomitantly with an intent to reduce its…”
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Head and neck cancer in the elderly: An overview on the treatment modalities by Syrigos, Kostas N, Karachalios, Dimitris, Karapanagiotou, Eleni M, Nutting, Christopher M, Manolopoulos, Leonidas, Harrington, Kevin J

“…Summary The percentage of elderly people with head and neck cancers (HNC) is rising due to increasing average lifespan. As with younger patients, elderly…”
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The Effectiveness of Atezolizumab in Metastatic Large Cell Neuroendocrine Carcinoma of the Lungs: Insights from the LANCE Pilot Study by Evangelou, Georgios, Trontzas, Ioannis P, Gkiozos, Ioannis, Vamvakaris, Ioannis, Paraskeva, Christina, Grammoustianou, Maria, Gomatou, Georgia, Tsamis, Ioannis, Vathiotis, Ioannis, Anagnostakis, Maximillian, Koliaraki, Vasiliki, Syrigos, Kostas

“…Large cell neuroendocrine carcinoma (LCNEC) presents significant treatment challenges due to its rarity and limited therapeutic options. The LANCE study was…”
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Capecitabine: an overview of the side effects and their management by Saif, Muhammad Wasif, Katirtzoglou, Nikos A, Syrigos, Kostas N

“…Xeloda (capecitabine), a thymidine phosphorylase activated fluoropyrimidine carbamate, is currently the only universally approved orally administered…”
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Epidemiology of active tuberculosis in lung cancer patients: a systematic review by Christopoulos, Antonis, Saif, Muhammad W, Sarris, Evangelos G, Syrigos, Kostas N

“…The aim of this review article is to evaluate the available literature concerning the prevalence of active tuberculosis in lung cancer patients. MEDLINE,…”
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A Benefit-Risk Assessment of Erlotinib in Non-Small-Cell Lung Cancer and Pancreatic Cancer by Mountzios, Giannis, Syrigos, Kostas N.

“…Non-small-cell lung cancer (NSCLC) and pancreatic cancer represent two major causes of cancer-related morbidity and mortality worldwide. Conventional cytotoxic…”
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Percentage Change in Plasma Cytokeratin 18 Is Associated with Clinical Outcomes in Patients Receiving Pemetrexed and Carboplatin for the Adenocarcinoma Subtype of NSCLC by Strimpakos, Alexios S, Banerji, Udai, Thavasu, Parames, Tsilimagou, Alexandra, Psyrri, Amanta, Syrigos, Kostas N

“…The adenocarcinoma subtype of non-small cell lung cancer (adeno-NSCLC) is routinely treated with chemotherapy if patients do not have molecular aberrations…”
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Vinorelbine Plus Cisplatin Versus Docetaxel Plus Gemcitabine in Advanced Non-Small-Cell Lung Cancer: A Phase III Randomized Trial by GEORGOULIAS, Vassilis, ARDAVANIS, Alexandros, POLYZOS, Aris, CHRISTOU, Anna, KAKOLYRIS, Stylianos, KOUROUSSIS, Charalambos, ANDROULAKIS, Nikolaos, SAMONIS, George, CHATZIDAKI, Dora, TSIAFAKI, Xanthi, AGELIDOU, Athina, MIXALOPOULOU, Penelope, ANAGNOSTOPOULOU, Ourania, ZIOTOPOULOS, Panagiotis, TOUBIS, Michael, SYRIGOS, Kostas, SAMARAS, Nikolaos

“…PURPOSE To compare the activity and tolerability of docetaxel/gemcitabine (DG) and vinorelbine/cisplatin (VC) combinations in chemotherapy-naive non-small-cell…”
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Hypersensitivity reactions to docetaxel: retrospective evaluation and development of a desensitization protocol by Syrigou, Ekaterini, Dannos, Ioannis, Kotteas, Elias, Makrilia, Nektaria, Tourkantonis, Ioannis, Dilana, Kalliopi, Gkiozos, Ioannis, Saif, Muhammad Wasif, Syrigos, Kostas N

“…Docetaxel (DT) is an extensively used taxane, frequently associated with hypersensitivity reactions. The aim of this study was to record the epidemiological…”
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