Search Results - "SYCHEV, D. A."

Effect of CYP3A4/5, ABCB1 gene polymorphisms on the residual equilibrium concentration of apixaban and bleeding in patients with non-valvular atrial fibrillation and deep vein thrombosis by Fedina, L. V., Sychev, I. N., Mirzaev, K. V., Vardanyan, A. V., Glagolev, S. V., Kachanova, A. A., Bochkov, P. O., Shevchenko, R. V., Tuchkova, S. N., Sychev, I. V., Abdullaev, S. P., Sychev, D A.

“…Aim . The aim of our study was to investigate the influence of polymorphic markers of CYP3A4*22 CYP3A4*22 ( c.522-191C>T, rs35599367 ), CYP3A5*3 ( c.219…”
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CYP2C1917 May Increase the Risk of Death Among Patients with an Acute Coronary Syndrome and Non-Valvular Atrial Fibrillation Who Receive Clopidogrel and Rivaroxaban by Sychev, D A, Baturina, O A, Mirzaev, K B, Rytkin, E, Ivashchenko, D V, Andreev, D A, Ryzhikova, K A, Grishina, E A, Bochkov, P O, Shevchenko, R V

“…The aim of this study is to assess the influence of gene and polymorphisms on clopidogrel antiplatelet activity, rivaroxaban concentration equilibrium, and…”
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Comparative clinical and economic evaluation of pharmacogenetic testing application for dabigatran in patients with atrial fibrillation by Abdullaev, Sh P, Mirzaev, K B, Sychev, D A

“…Aim. To evaluate the clinical and economic feasibility of pharmacogenetic testing (PGT) for dabigataran etexilate administration in the treatment of atrial…”
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Micro-RNA as a new biomarker of activity of the cytochrome system P-450: significance for predicting the antiplatelet action of P2Y12 receptor inhibitors by Rytkin, E I, Mirzaev, K B, Bure, I V, Sychev, D A

“…MicroRNAs are short non - coding RNAs that correlate with the levels of platelet activation which can be utilized as a biomarker when guiding P2Y12 inhibitors…”
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The pharmacogenetics of hypoglycemia and the glycemic variability at the patients ith type 2 diabetes mellitus by Chernikova, N A, Kamynina, L L, Ametov, A S, Sychev, D A, Grishina, E A, Ryzhikova, K A

“…To investigate the link between the hypoglycemia (registrated accurately by the professional Continuous Glucose Monitoring CGM; severe hypoglycemia at home)…”
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Effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders and comorbid alcohol use disorder by Zastrozhin, M S, Skryabin, V Y, Smirnov, V V, Grishina, E A, Ryzhikova, K A, Chumakov, E M, Bryun, E A, Sychev, D A

“…The objective of the study was to investigate the effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders…”
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Results of decision support system implementation for prescribing anticoagulants to patients with atrial fibrillation in hospital by Chernov, A A, Kleymenova, E B, Sychev, D A, Yashina, L P, Nigmatkulova, M D, Otdelenov, V A, Payushchik, S A

“…In 819% of patients with atrial fibrillation (AF) with anticoagulant therapy (ACT), hemorrhagic complications occur, including due to excess doses of AC. At…”
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Genetic features of a patient may influence the efficacy and safety profile of a medicinal product by Sychev, D. A.

“…Identification of the genetic features that determine a patient’s individual response to a medicinal product and provision of this information to a doctor…”
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Review of the book “Practical issues of rational antibacterial therapy” by Sychev, D. A.

“…In 2023, the book “Practical Issues of Rational Antibacterial Therapy” under general ed. Yarovoy SK, Khokhlov AL, was published. This monograph is devoted to…”
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Analysis of carrying clinically significant allelic variants of TPMT and DPYD genes associated with the response to drug therapy in cancer practice among 9 ethnic groups of the Russian Federation by Mirzaev, K B, Fedorinov, D S, Akmalova, K A, Abdullaev, S P, Kachanova, A A, Sozaeva, Z A, Grishina, E A, Shuev, G N, Kitaeva, E Y, Shprakh, V V, Suleymanov, S S, Bolieva, L Z, Sozaeva, M S, Zhuchkova, S M, Gimaldinova, N E, Sidukova, E E, Burashnikova, I S, Shikaleva, A A, Zabudskaya, K G, Sychev, D A

“…To study the peculiarities of carrying clinically significant allelic variants of TPMT and DPYD genes associated with the response to drug therapy in cancer…”
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The frequency of CYP2C19 genetic polymorphisms in Russian patients with peptic ulcers treated with proton pump inhibitors by Sychev, D A, Denisenko, N P, Sizova, Z M, Grachev, A V, Velikolug, K A

“…Proton pump inhibitors, which are widely used as acid-inhibitory agents for the treatment of peptic ulcers, are mainly metabolized by 2C19 isoenzyme of…”
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Pharmacogenetics of alcohol addiction: current perspectives by Zastrozhin, M S, Skryabin, V Yu, Miroshkin, S S, Bryun, E A, Sychev, D A

“…Genetics of alcohol addiction is currently a contradictive and complex field, where data in the most studies reflect methods' limitations rather than…”
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Polypragmasy: A clinical pharmacologist's view by Sychev, D A, Otdelеnov, V A, Krasnova, N M, Ilyina, E S

“…In the modern world, there is a rapid advance in the design and clinical introduction of a huge number of drugs that are able to cure a patient or to improve…”
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Use of pharmacogenetic testing to prevent adverse drug reactions during statin therapy by Rumyantsev, N A, Kukes, V G, Kazakov, R E, Rumyantsev, A A, Sychev, D A

“…The number of patients receiving statins increases every year and due to the fact that they should take statins during their lives, the problem of their safety…”
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Impact of pharmacogenetic testing on the risk of bleedings and excessive hypocoagulation episodes in the use of warfarin: the first meta-analysis of Russian prospective studies by Sychev, D A, Ivashchenko, D V, Rusin, I V

“…To perform a meta-analysis of Russian prospective studies comparing the pharmacogenetic versus conventional warfarin dosing procedures. Publications were…”
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Lattice Study of the Equation of State of a Rotating Gluon Plasma by Braguta, V. V., Kudrov, I. E., Roenko, A. A., Sychev, D. A., Chernodub, M. N.

“…The effect of uniform rotation on the equation of state of gluodynamics has been studied in lattice simulation. To this end, the system has been considered in…”
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Information Security in the Automated Production Control System at PAO Koks by Malyshenko, V. V., Sychev, D. A.

“…Information security in the automated production control system at PAO Koks is discussed. Organizational and engineering aspects of security required to ensure…”
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Clinical and pharmacological technologies of personalized medicine: what now and what will happen? by Sychev, D. A.

“…«Omic» biomarkers are promising tools for personalizing pharmacotherapy, including and mental illness because allow predicting an individual profile of the…”
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Optimizing the prophylaxis of hospital-acquired deep vein thrombosis and pulmonary thromboembolism by Nazarenko, G I, Kleymenova, E B, Payushchik, S A, Otdelеnov, V A, Sychev, D A

“…To reduce the number of preventable hospital-acquired venous thromboembolic events (HA-VTE) and to improve the quality of VTE prophylaxis at multiprofile…”
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Antibiotic-Associated Drug-Induced Liver Injury in Critically Ill Children: A Prospective Observational Study by Vlasova, A. V., Shubina, Yu. F., Sychev, D. A.

“…INTRODUCTION.  Drug-induced liver injury (DILI) is associated, among other things, with the use of antibiotics. Children with DILI are at risk of acute liver…”
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