Search Results - "SWEDLUND, Brad"

Homologous Recombination Deficiency as an Ovarian Cancer Biomarker in a Real-World Cohort: Validation of Decentralized Genomic Profiling by Denkert, Carsten, Romey, Marcel, Swedlund, Brad, Hattesohl, Akira, Teply-Szymanski, Julia, Kommoss, Stefan, Kaiser, Kristin, Staebler, Annette, du Bois, Andreas, Grass, Albert, Knappmeyer, Christiane, Heitz, Florian, Solimeno, Cara, Ebel, Thomas, Harter, Philipp, Marmé, Frederik, Jank, Paul, Gaiser, Timo, Neff, Chris, Wagner, Uwe, Timms, Kirsten M, Rodepeter, Fiona

“…The diagnostic evaluation of homologous recombination deficiency (HRD) is central to define targeted therapy strategies for patients with ovarian carcinoma. We…”
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Sorbitol as the Primary Carbon Source for the Growth of Embryogenic Callus of Maize by Brad Swedlund, Locy, Robert D.

“…The effects of various carbon sources on initiation and maintenance of embryogenic callus of maize (Zea mays L.) and on the regeneration of plants from…”
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The landscape of BRCA1 and BRCA2 large rearrangements in an international cohort of over 20000 ovarian tumors identified using next‐generation sequencing by Jones, Melanie A, Timms, Kirsten M, Hatcher, Shanell, Cogan, Elizabeth S, Comeaux, Matthew S, Perry, Michael, Morris, Brian, Swedlund, Brad, Elks, Cathy E, Pierre Lao‐Sirieix, Dearden, Simon, Egile, Coumaran, Brown, Jessica S, Harrington, Elizabeth A, Hodgson, Darren, Stern, Matt, Slavin, Thomas P, Debora Mancini‐DiNardo

“…BackgroundApproximately half of ovarian tumors have defects within the homologous recombination repair pathway. Tumors carrying pathogenic variants (PVs) in…”
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The landscape of BRCA1 and BRCA2 large rearrangements in an international cohort of over 20 000 ovarian tumors identified using next‐generation sequencing by Jones, Melanie A., Timms, Kirsten M., Hatcher, Shanell, Cogan, Elizabeth S., Comeaux, Matthew S., Perry, Michael, Morris, Brian, Swedlund, Brad, Elks, Cathy E., Lao‐Sirieix, Pierre, Dearden, Simon, Egile, Coumaran, Brown, Jessica S., Harrington, Elizabeth A., Hodgson, Darren, Stern, Matt, Slavin, Thomas P., Mancini‐DiNardo, Debora

“…Background Approximately half of ovarian tumors have defects within the homologous recombination repair pathway. Tumors carrying pathogenic variants (PVs) in…”
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Homologous Recombination Deficiency as an Ovarian Cancer Biomarker in a Real-World Cohort by Denkert, Carsten, Romey, Marcel, Swedlund, Brad, Hattesohl, Akira, Teply-Szymanski, Julia, Kommoss, Stefan, Kaiser, Kristin, Staebler, Annette, du Bois, Andreas, Grass, Albert, Knappmeyer, Christiane, Heitz, Florian, Solimeno, Cara, Ebel, Thomas, Harter, Philipp, Marmé, Frederik, Jank, Paul, Gaiser, Timo, Neff, Chris, Wagner, Uwe, Timms, Kirsten M., Rodepeter, Fiona

“…The diagnostic evaluation of homologous recombination deficiency (HRD) is central to define targeted therapy strategies for patients with ovarian carcinoma. We…”
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A candidate prostate cancer susceptibility gene at chromosome 17p by Tavtigian, Sean V, Simard, Jacques, Teng, David H.F, Abtin, Vicki, Baumgard, Michelle, Beck, Audrey, Camp, Nicola J, Carillo, Arlene R, Chen, Yang, Dayananth, Priya, Desrochers, Marc, Dumont, Martine, Farnham, James M, Frank, David, Frye, Cheryl, Ghaffari, Siavash, Gupte, Jamila S, Hu, Rong, Iliev, Diana, Janecki, Teresa, Kort, Edward N, Laity, Kirsten E, Leavitt, Amber, Leblanc, Gilles, McArthur-Morrison, Jodi, Pederson, Amy, Penn, Brandon, Peterson, Kelly T, Reid, Julia E, Richards, Sam, Schroeder, Marianne, Smith, Richard, Snyder, Sarah C, Swedlund, Brad, Swensen, Jeff, Thomas, Alun, Tranchant, Martine, Woodland, Ann-Marie, Labrie, Fernand, Skolnick, Mark H, Neuhausen, Susan, Rommens, Johanna, Cannon-Albright, Lisa A

“…It is difficult to identify genes that predispose to prostate cancer due to late age at diagnosis, presence of phenocopies within high-risk pedigrees and…”
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BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines by WONG, Alexander K. C, SHANAHAN, Frances, SMITH, Richard, SALADA, Grant, CARILLO, Arlene, LAITY, Kirsten, GUPTE, Jamila, SWEDLUND, Brad, TAVTIGIAN, Sean V, TENG, David H-F, LEES, Emma, YUAN CHEN, LUBING LIAN, PHUONG HA, HENDRICKS, Kristin, GHAFFARI, Siavash, ILIEV, Diana, PENN, Brandon, WOODLAND, Anne-Marie

“…Human BRG1 is a component of the evolutionarily conserved SWI-SNF chromatin remodeling complex. BRG1 has been implicated in growth control through its…”
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MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines by TENG, D. H.-F, HU, R, ELLIS, L, EL-NAGGAR, A, FRAZIER, M, JASSER, S, LANGFORD, L. A, LEE, J, MILLS, G. B, PERSHOUSE, M. A, POLLACK, R. E, TORNOS, C, LIN, H, TRONCOSO, P, YUNG, W. K. A, FUJII, G, BERSON, A, BOOKSTEIN, R, BOLEN, J. B, TAVTIGIAN, S. V, STECK, P. A, DAVIS, T, ILIEV, D, FRYE, C, SWEDLUND, B, HANSEN, K. L, VINSON, V. L, GUMPPER, K. L

“…A candidate tumor suppressor gene, MMAC1/PTEN, located in human chromosome band 10q23, was recently identified based on sequence alterations observed in…”
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Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor by TENG, D. H.-F, PERRY, W. L, HU, R, JAMMULAPATI, S, JANECKI, T, LEAVITT, A, MITCHELL, J. T, PERO, R, SEXTON, D, SCHROEDER, M, SU, P.-H, SWEDLUND, B, HOGAN, J. K, KYRIAKIS, J. M, AVRUCH, J, BARTEL, P, WONG, A. K. C, OLIPHANT, A, THOMAS, A, SKOLNICK, M. H, TAVTIGIAN, S. V, BAUMGARD, M, BELL, R, BERRY, S, DAVIS, T, FRANK, D, FRYE, C, HATTIER, T

“…Mitogen-activated protein kinases function in signal transduction pathways that are involved in controlling key cellular processes in many organisms. A…”
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Low incidence of BRCA2 mutations in breast carcinoma and other cancers by Teng, David H.-R, Bogden, Robert, Mitchell, Jeffrey, Baumgard, Michelle, Bell, Russell, Berry, Simin, Davis, Thaylon, Ha, Phuong C, Kehrer, Robert, Jammulapati, Srikanth, Chen, Qian, Offit, Kenneth, Skolnick, Mark H, Tavtigian, Sean V, Jhanwar, Suresh, Swedlund, Brad, Wong, Alexander K.C, Kamb, Alexander

“…Inherited mutant alleles of familial tumour suppressor genes predispose individuals to particular types of cancer. In addition to an involvement in inherited…”
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Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13 by COUCH, F. J, ROMMENS, J. M, FARID, L, FRYE, C, HATTIER, T, JANECKI, T, JIANG, P, KEHRER, R, LEBLANC, J.-F, MCARTHUR-MORRISON, J, MCSWEENEY, D, MIKI, Y, NEUHAUSEN, S. L, PENG, Y, SAMSON, C, SCHROEDER, M, SNYDER, S. C, STRINGFELLOW, M, STROUP, C, SWEDLUND, B, SWENSEN, J, TENG, D, THAKUR, S, BELANGER, C, TRAN, T, TRANCHANT, M, WELVER-FELDHAUS, J, WONG, A. K. C, SHIZUYA, H, LABRIE, F, SKOLNICK, M. H, GOLDGAR, D. E, KAMB, A, WEBER, B. L, DUMONT, M, TAVTIGIAN, S. V, SIMARD, J, ABEL, K, BELL, R, BERRY, S, BOGDEN, R, CANNON-ALBRIGHT, L

“…An integrated approach involving physical mapping, identification of transcribed sequences, and computational analysis of genomic sequence was used to generate…”
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Generation of an Integrated Transcription Map of theBRCA2Region on Chromosome 13q12–q13 by Couch, Fergus J., Rommens, Johanna M., Neuhausen, Susan L., Bélanger, Carole, Dumont, Martine, Abel, Kenneth, Bell, Russell, Berry, Simon, Bogden, Robert, Cannon-Albright, Lisa, Farid, Linda, Frye, Cheryl, Hattier, Thomas, Janecki, Teresa, Jiang, Ping, Kehrer, Robert, Leblanc, Jean-Francois, McArthur-Morrison, Jodi, Meney, David, Miki, Yoshio, Peng, Yi, Samson, Carolle, Schroeder, Marianne, Snyder, Sarah C., Stringfellow, Michael, Stroup, Carrie, Swedlund, Brad, Swensen, Jeff, Teng, David, Thakur, Sanjay, Tran, Thanh, Tranchant, Martine, Welver-Feldhaus, Jane, Wong, Alexander K.C., Shizuya, Hiroake, Labrie, Fernand, Skolnick, Mark H., Goldgar, David E., Kamb, Alexander, Weber, Barbara L., Tavtigian, Sean V., Simard, Jacques

“…An integrated approach involving physical mapping, identification of transcribed sequences, and computational analysis of genomic sequence was used to generate…”
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