Search Results - "SWATTON, Jane E."

Using chemical probes to investigate the sub-inhibitory effects of azithromycin by Glansdorp, Freija G, Spandl, Richard J, Swatton, Jane E, Loiseleur, Olivier, Welch, Martin, Spring, David R

“…The antibacterial drug azithromycin has clinically beneficial effects at sub-inhibitory concentrations for the treatment of conditions characterized by chronic…”
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Fast Biphasic Regulation of Type 3 Inositol Trisphosphate Receptors by Cytosolic Calcium by Swatton, Jane E., Taylor, Colin W.

“…In cytosol-like medium (CLM) with a free [Ca2+] of 200 nm, a supramaximal concentration of inositol 1,4,5-trisphosphate (IP3) (30 μm) evoked 45Ca2+ release…”
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Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain by . Swatton, Jane E, Sellers, Lynda A., Faull, Richard L.M., Holland, Anthony, Iritani, Shuji, Bahn, Sabine

“…Introduction Abnormal phosphorylation of tau is a feature of Alzheimer's disease (AD), which develops prematurely in Down syndrome (DS) patients. Cognitive…”
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Variations on a theme: diverse N-acyl homoserine lactone-mediated quorum sensing mechanisms in Gram-negative bacteria by SMITH, DEBRA, WANG, JIN-HONG, SWATTON, JANE E., DAVENPORT, PETER, PRICE, BIANCA, MIKKELSEN, HELGA, STICKLAND, HANNAH, NISHIKAWA, KAHOKO, GARDIOL, NOÉMIE, SPRING, DAVID R., WELCH, MARTIN

“…Many Gram-negative bacteria employ a mechanism of cell-cell communication known as quorum sensing (QS). The role of QS is to enable the cells in a culture to…”
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Cell-cell communication in Gram-negative bacteria by Welch, Martin, Mikkelsen, Helga, Swatton, Jane E, Smith, Debra, Thomas, Gemma L, Glansdorp, Freija G, Spring, David R

“…Over the last decade or so, a wealth of research has established that bacteria communicate with one another using small molecules. These signals enable the…”
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Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans by Howlett, D R, Perry, A E, Godfrey, F, Swatton, J E, Jennings, K H, Spitzfaden, C, Wadsworth, H, Wood, S J, Markwell, R E

“…A series of benzofuran derivatives have been identified as inhibitors of fibril formation in the beta-amyloid peptide. The activity of these compounds has been…”
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Type 3 inositol trisphosphate receptors in RINm5F cells are biphasically regulated by cytosolic Ca2+ and mediate quantal Ca2+ mobilization by Swatton, J E, Morris, S A, Cardy, T J, Taylor, C W

“…There are three subtypes of mammalian Ins(1,4,5)P(3) (InsP(3)) receptor, each of which forms an intracellular Ca(2+) channel. Biphasic regulation of InsP(3)…”
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Functional properties of Drosophila inositol trisphosphate receptors by SWATTON, Jane E., MORRIS, Stephen A., WISSING, Frank, TAYLOR, Colin W.

“…The functional properties of the only inositol trisphosphate (IP3) receptor subtype expressed in Drosophila were examined in permeabilized S2 cells. The IP3…”
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Functional properties of Drosophila inositol trisphosphate receptors by Swatton, J E, Morris, S A, Wissing, F, Taylor, C W

“…The functional properties of the only inositol trisphosphate (IP(3)) receptor subtype expressed in Drosophila were examined in permeabilized S2 cells. The…”
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Type 3 inositol trisphosphate receptors in RINm5F cells are biphasically regulated by cytosolic Ca2+ and mediate quantal Ca2+ mobilization by SWATTON, Jane E., MORRIS, Stephen A., CARDY, Thomas J. A., TAYLOR, Colin W.

“…There are three subtypes of mammalian Ins(1,4,5)P3 (InsP3) receptor, each of which forms an intracellular Ca2+ channel. Biphasic regulation of InsP3 receptors…”
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Inhibition of fibril formation in β-amyloid peptide by a novel series of benzofurans by HOWLETT, David R., PERRY, Amanda E., GODFREY, Fiona, SWATTON, Jane E., JENNINGS, Kevin H., SPITZFADEN, Claus, WADSWORTH, Harry, WOOD, Stephen J., MARKWELL, Roger E.

“…A series of benzofuran derivatives have been identified as inhibitors of fibril formation in the β-amyloid peptide. The activity of these compounds has been…”
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