Search Results - "SWART, Martha"
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1
Coadministration of Oral Cyclosporin A Enables Oral Therapy with Paclitaxel
Published in Clinical cancer research (01-11-1999)“…i.v. paclitaxel is inconvenient and associated with significant and poorly predictable side effects largely due to the pharmaceutical vehicle Cremophor EL…”
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Journal Article -
2
Phase I and Pharmacokinetic Study of Oral Paclitaxel
Published in Journal of clinical oncology (01-06-2000)“…To investigate dose escalation of oral paclitaxel in combination with dose increment and scheduling of cyclosporine (CsA) to improve the systemic exposure to…”
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Journal Article -
3
Phase I Clinical and Pharmacokinetic Study of Oral S-1 in Patients With Advanced Solid Tumors
Published in Journal of clinical oncology (01-07-2000)“…To investigate the side effects, determine the maximum-tolerated dose (MTD), and study the pharmacokinetics of S-1, an oral fluoropyrimidine-based…”
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Journal Article -
4
Phase I and Pharmacokinetic Study of Irinotecan Administered as a Low-Dose, Continuous Intravenous Infusion Over 14 Days in Patients With Malignant Solid Tumors
Published in Journal of clinical oncology (01-06-1999)“…To evaluate the feasibility of administering irinotecan as a continuous intravenous infusion for 14 to 21 days. Patients with solid tumors refractory to…”
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Journal Article -
5
A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A
Published in Cancer chemotherapy and pharmacology (01-04-2001)“…To investigate dose escalation of bi-daily (b.i.d.) oral paclitaxel in combination with cyclosporin A in order to improve and prolong the systemic exposure to…”
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Journal Article -
6
The effect of different doses of cyclosporin A on the systemic exposure of orally administered paclitaxel
Published in Anti-cancer drugs (01-04-2001)“…The objective of this study was to define the minimally effective dose of cyclosporin A (CsA) that would result in a maximal increase of the systemic exposure…”
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Journal Article -
7
Metabolism and excretion of paclitaxel after oral administration in combination with cyclosporin A and after i.v. administration
Published in Anti-cancer drugs (01-11-2000)“…The objective of this study was to compare the quantitative excretion of paclitaxel and metabolites after i.v. and oral drug administration. Four patients…”
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Journal Article -
8
PHARMACOKINETICS OF PACLITAXEL ADMINISTERED AS A 3-HOUR OR 96-HOUR INFUSION
Published in Pharmacological research (01-07-1999)“…Aim: To investigate the pharmacokinetics of paclitaxel (PaxeneTM) administered to patients with advanced breast or ovarian cancer and to document safety and…”
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Journal Article -
9
A Population Vulnerability Analysis of South African Black Rhinoceros Diceros Bicornis
Published 01-01-1994“…To determine the vulnerability of black rhinoceros populations in South Africa it was necessary to study all aspects of population biology. Since most of the…”
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Dissertation -
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n Genetiese Evaluering Van Nege reënboogforelbevolkings in Suid-Afrika
Published 01-01-1990“…Fishery managers work toward effective management of fishery resources in the face of diverse demands for recreational fishing and preservation of genetic…”
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Dissertation