Search Results - "SWANSON, JOY E."

Disruption of Mouse Cytochrome P450 4f14 (Cyp4f14 Gene) Causes Severe Perturbations in Vitamin E Metabolism by Bardowell, Sabrina A., Duan, Faping, Manor, Danny, Swanson, Joy E., Parker, Robert S.

“…Background: Human CYP4F2 metabolizes vitamin E, but its role in vivo is unknown. Results: Disruption of Cyp4f14, a murine ortholog of CYP4F2, severely alters…”
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Dietary flavonoids with a catechol structure increase α-tocopherol in rats and protect the vitamin from oxidation in vitro by Frank, Jan, Budek, Alicja, Lundh, Torbjörn, Parker, Robert S., Swanson, Joy E., Lourenço, Cátia F., Gago, Bruno, Laranjinha, João, Vessby, Bengt, Kamal-Eldin, Afaf

“…To identify dietary phenolic compounds capable of improving vitamin E status, male Sprague-Dawley rats were fed for 4 weeks either a basal diet (control) with…”
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Cereal alkylresorcinols elevate gamma-tocopherol levels in rats and inhibit gamma-tocopherol metabolism in vitro by Ross, Alastair B, Chen, Yan, Frank, Jan, Swanson, Joy E, Parker, Robert S, Kozubek, Arkadiusz, Lundh, Torbjörn, Vessby, Bengt, Aman, Per, Kamal-Eldin, Afaf

“…Alkylresorcinols (AR) are a class of amphiphilic phenolic lipids present in high amounts in wheat and rye bran. They have been reported to be both growth…”
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Discovery, Characterization, and Significance of the Cytochrome P450 ω-Hydroxylase Pathway of Vitamin E Catabolism by PARKER, ROBERT S., SONTAG, TIMOTHY J., SWANSON, JOY E., McCORMICK, CHARLES C.

“…: Tocopherols are known to undergo metabolism to phytyl chain‐shortened metabolites excreted in urine. We sought to characterize the pathway, including…”
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Long-chain carboxychromanols are the major metabolites of tocopherols and tocotrienols in A549 lung epithelial cells but not HepG2 cells by You, Cha-Sook, Sontag, Timothy J, Swanson, Joy E, Parker, Robert S

“…Human lung type II cell derived A549 epithelial cancer cells and HepG2 hepatocytes constitutively express cytochrome P4504F2, a P450 we previously identified…”
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Dietary (+)-catechin and BHT markedly increase alpha-tocopherol concentrations in rats by a tocopherol-omega-hydroxylase-independent mechanism by Frank, Jan, Lundh, Torbjörn, Parker, Robert S, Swanson, Joy E, Vessby, Bengt, Kamal-Eldin, Afaf

“…The effects of dietary (+)-catechin (CAT) and BHT on plasma and tissue concentrations of alpha-tocopherol (alpha-T), gamma-tocopherol (gamma-T) and cholesterol…”
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Bioavailability of carotenoids in human subjects by Parker, Robert S., Swanson, Joy E., You, Cha-Sook, Edwards, Alison J., Huang, Tina

“…There is growing need for accurate information regarding the bioavailability of carotenoids, both with respect to carotenoids per se and to the vitamin A value…”
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A novel extrinsic reference method for assessing the vitamin A value of plant foods by EDWARDS, Alison J, YOU, Cha-Sook, SWANSON, Joy E, PARKER, Robert S

“…The amounts of vitamin A that are metabolically derived from specific carotene-containing foods are largely unknown. We sought to develop an improved method…”
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Dose-Dependent Effects of Dietary α- and γ-Tocopherols on Genetic Instability in Mouse Mutatect Tumors by Soo, Catherine C.-Y., Haqqani, Arsalan S., Hidiroglou, Nick, Swanson, Joy E., Parker, Robert S., Birnboim, H. Chaim

“…Vitamin E in foodstuffs is a mixture of tocopherols. In mouse Mutatect tumors, a model designed to detect DNA mutations, the hypoxanthine…”
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Bioavailability and vitamin A value of carotenes from red palm oil assessed by an extrinsic isotope reference method by You, Cha‐Sook, Parker, Robert S, Swanson, Joy E

“…Red palm oil (RPO) contains high concentrations of β‐ and α‐carotene, and is presumed to possess a higher vitamin A value than other foods. The objective was…”
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Evidence of cis-trans isomerization of 9-cis-beta-carotene during absorption in humans by You, CS, Parker, RS, Goodman, KJ, Swanson, JE, Corso, TN

“…Absorption and metabolism of [13C]9-cis-beta-carotene ([13C]9c beta C) was studied in three subjects after a single oral dose. Subjects given 1.0 mg…”
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Evidence of a role for fat-free body mass in modulation of plasma carotenoid concentrations in older men: studies with hydrodensitometry by Zhu, Y I, Hsieh, W C, Parker, R S, Herraiz, L A, Haas, J D, Swanson, J E, Roe, D A

“…We examined the relationship between body composition and changes in plasma carotenoid concentration in response to dietary carotenoid restriction or…”
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Knockout of CYP4f14 causes severe perturbations in vitamin E metabolism and results in tissue accumulation of vitamin E in the mouse by Bardowell, Sabrina Anne, Duan, Faping, Swanson, Joy E., Manor, Danny, Parker, Robert S.

“…Abstract only Vitamin E is a family of eight naturally‐occurring lipophilic antioxidants, of which one, α‐tocopherol (TOH), selectively accumulates in…”
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Cytochrome P4503A-Dependent Metabolism of Tocopherols and Inhibition by Sesamin by Parker, Robert S., Sontag, Timothy J., Swanson, Joy E.

“…Carboxychroman metabolites of the major dietary tocopherols are excreted in human urine, but the mechanism of their synthesis is unknown. We employed…”
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Thermodynamics of mixing of phosphatidylserine/phosphatidylcholine from measurements of high-affinity calcium binding by Swanson, Joy E, Feigenson, Gerald W

“…A simple model system is described that allows measurement of equilibrium Ca2+ binding to multilamellar vesicle mixtures of palmitoyloleoylphosphatidylserine…”
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A Novel 5′-Carboxychroman Metabolite of γ-Tocopherol Secreted by HepG2 Cells and Excreted in Human Urine by Parker, Robert S., Swanson, Joy E.

“…HepG2 cells were incubated with a medium containing fetal bovine serum enriched with RRR-γ-tocopherol (γ-TOH). After 48 h the medium was extracted and analyzed…”
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A novel extrinsic reference method for assessing the vitamin A value of plant foods123 by Edwards, Alison J, You, Cha-Sook, Swanson, Joy E, Parker, Robert S

“…The amounts of vitamin A that are metabolically derived from specific carotene-containing foods are largely unknown. We sought to develop an improved method…”
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Dose-Dependent Effects of Dietary  - and  -Tocopherols on Genetic Instability in Mouse Mutatect Tumors by Soo, C. C.-Y., Haqqani, A. S., Hidiroglou, N., Swanson, J. E., Parker, R. S., Birnboim, H. C.

“…Vitamin E in foodstuffs is a mixture of tocopherols. In mouse Mutatect tumors, a model designed to detect DNA mutations, the hypoxanthine…”
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Alpha- and beta-carotene from a commercial puree are more bioavailable to humans than from boiled-mashed carrots, as determined using an extrinsic stable isotope reference method by Edwards, Alison J, Nguyen, Christine H, You, Cha-Sook, Swanson, Joy E, Emenhiser, Curt, Parker, Robert S

“…The extent to which processing affects the carotene or vitamin A value of foods is poorly understood. An extrinsic reference method was used to estimate the…”
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Assessing metabolism of beta-[13C]carotene using high-precision isotope ratio mass spectrometry by Parker, R S, Brenna, J T, Swanson, J E, Goodman, K J, Marmor, B

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