Search Results - "SVENSSON, T. H"

EPA Guidance on tobacco dependence and strategies for smoking cessation in people with mental illness by Rüther, T, Bobes, J, De Hert, M, Svensson, T.H, Mann, K, Batra, A, Gorwood, P, Möller, H.J

“…Abstract Tobacco dependence is the most common substance use disorder in adults with mental illness. The prevalence rates for tobacco dependence are two to…”
Get full text

Lumateperone-mediated effects on prefrontal glutamatergic receptor-mediated neurotransmission: A dopamine D1 receptor dependent mechanism by Titulaer, J, Radhe, O, Danielsson, K, Dutheil, S, Marcus, MM, Jardemark, K, Svensson, TH, Snyder, GL, Ericson, M, Davis, RE, Konradsson-Geuken, Å

“…•Lumateperone had an antipsychotic-like effect in the CAR test.•Lumateperone facilitated NMDA and AMPA receptor-mediated currents in the rat mPFC.•NMDA and…”
Get full text

N-methyl- d-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens by Schilström, B, Nomikos, G.G, Nisell, M, Hertel, P, Svensson, T.H

“…Systemic nicotine enhances burst firing of dopamine neurons in the ventral tegmental area and dopamine release in the nucleus accumbens, mainly via stimulation…”
Get full text

Active immunization against nicotine prevents reinstatement of nicotine-seeking behavior in rats by Lindblom, N, de Villiers, S H L, Kalayanov, G, Gordon, S, Johansson, A M, Svensson, T H

“…The presently available pharmaceutical aids in smoking cessation possess a rather limited effectiveness. Therefore, we have synthesized a series of…”
Get more information

Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo by Chergui, K, Charléty, P J, Akaoka, H, Saunier, C F, Brunet, J L, Buda, M, Svensson, T H, Chouvet, G

“…Midbrain dopamine neurons in vivo discharge in a single-spike firing pattern or in a burst-firing pattern. Such activity in vivo strikingly contrasts with the…”
Get more information

Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons by Schilström, B, Mameli-Engvall, M, Rawal, N, Grillner, P, Jardemark, K, Svensson, T.H

“…In the present study, using single cell recordings in vivo and intracellular recordings in vitro from midbrain slices, the role of N-methyl- d-aspartate (NMDA)…”
Get full text

Active immunization against nicotine suppresses nicotine-induced dopamine release in the rat nucleus accumbens shell by de Villiers, S H L, Lindblom, N, Kalayanov, G, Gordon, S, Malmerfelt, A, Johansson, A M, Svensson, T H

“…Tobacco smoking is the largest preventable cause of morbidity and premature mortality in the world. Although its medical consequences are well documented,…”
Get more information

Behavioral manifestations of the nicotine abstinence syndrome in the rat : peripheral versus central mechanisms by HILDEBRAND, B. E, NOMIKOS, G. G, BONDJERS, C, NISELL, M, SVENSSON, T. H

“…The nicotine abstinence syndrome was studied in the rat utilizing a modified rating scale of the opiate abstinence syndrome. Rats were infused with 10.27 mg/kg…”
Get full text

Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition by UGEDO, L, GRENHOFF, J, SVENSSON, T. H

“…The effect of systemic administration of ritanserin (R 55667), a 5-hydroxytryptamine (5-HT2) receptor antagonist, on midbrain dopamine (DA) neurons was studied…”
Get full text

Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome by Hildebrand, Bengt E, Nomikos, George G, Hertel, Peter, Schilström, Björn, Svensson, Torgny H

“…Mesolimbocortical dopamine (DA) neurotransmission is important in the mediation of the dependence-producing actions of nicotine and other drugs of abuse…”
Get full text

Nicotine and food induced dopamine release in the nucleus accumbens of the rat: Putative role of α7 nicotinic receptors in the ventral tegmental area by Schilström, B., Svensson, H.M., Svensson, T.H., Nomikos, G.G.

“…We have recently shown that the stimulatory effect of nicotine on dopamine output in the nucleus accumbens is largely dependent upon an enhanced glutamate…”
Get full text

Selective noradrenaline reuptake inhibition enhances serotonergic neuronal activity and transmitter release in the rat forebrain by Linnér, L, Wiker, C, Arborelius, L, Schalling, M, Svensson, T H

“…Present pharmacotherapy of major depression is, in principle, based on enhancement of central monoaminergic neurotransmission. Clinical studies utilizing…”
Get full text

Muscarinic receptors depress GABAergic synaptic transmission in rat midbrain dopamine neurons by Grillner, P, Berretta, N, Bernardi, G, Svensson, T.H, Mercuri, N.B

“…The effects of muscarine and nicotine on evoked and spontaneous release of GABA were studied using intracellular and whole-cell patch-clamp recordings from rat…”
Get full text

Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens by NISELL, M, MARCUS, M, NOMIKOS, G. G, SVENSSON, T. H

“…Like several drugs of abuse, nicotine increase dopamine (DA) release in the nucleus accumbens (NAC). In the present study, the effects of acute and chronic…”
Get full text

Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat by Panagis, G., Nisell, M., Nomikos, G.G., Chergui, K., Svensson, T.H.

“…Systemic administration of nicotine has been shown to increase locomotor activity in rats, an effect which is enhanced by chronic pretreatment with the drug…”
Get full text

Behavioral and Biochemical Manifestations of Mecamylamine-Precipitated Nicotine Withdrawal in the Rat: Role of Nicotinic Receptors in the Ventral Tegmental Area by Hildebrand, Bengt E, Panagis, George, Svensson, Torgny H, Nomikos, George G

“…Brain mesolimbic dopamine (DA) neurons are considered critical for the dependence-producing action of nicotine, and its stimulatory effect on behavior and DA…”
Get full text

Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat by GRENHOFF, J, NISELL, M, FERRE, S, ASTON-JONES, G, SVENSSON, T. H

Get full text

Lumateperone-mediated effects on prefrontal glutamatergic receptor-mediated neurotransmission: A dopamine D-1 receptor dependent mechanism by Titulaer, Joep, Radhe, O., Danielsson, K., Dutheil, S., Marcus, M. M., Jardemark, K., Svensson, T. H., Snyder, G. L., Ericson, M., Davis, R. E., Konradsson-Geuken, Åsa

“…Lumateperone is a novel drug approved for the treatment of schizophrenia in adults and depressive episodes associated with bipolar depression in adults, as…”
Get full text

Peripheral, autonomic regulation of locus coeruleus noradrenergic neurons in brain: putative implications for psychiatry and psychopharmacology by SVENSSON, T. H

“…In 1946 von Euler identified the major transmitter of sympathetic nerve fibers, norepinephrine (NE), and about a decade later Vogt (1954) provided the first…”
Get full text

Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons studied in vivo by Murase, S, Grenhoff, J, Chouvet, G, Gonon, F G, Svensson, T H

“…The influence of the medial prefrontal cortex (PFC) on mesolimbic dopamine activity was studied with electrophysiological techniques and in vivo voltammetry in…”
Get more information