Success of trabeculotomy in patients with congenital glaucoma operated on within 3 months of birth

To determine the efficacy and safety of trabeculotomy in congenital glaucoma patients operated on within first 3 months of birth. A total of 36 eyes of 24 patients with congenital glaucoma, who underwent primary trabeculotomy within first 3 months of birth were included. Preoperative and postoperati...

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Bibliographic Details
Published in:	Eye (London) Vol. 21; no. 4; pp. 459 - 464
Main Authors:	YALVAC, I. S, SATANA, B, SUVEREN, A, EKSIOGLU, U, DUMAN, S
Format:	Journal Article
Language:	English
Published:	Basingstoke Nature Publishing Group 01-04-2007
Subjects:	Biological and medical sciences Cornea - pathology Female Glaucoma Glaucoma - congenital Glaucoma - physiopathology Glaucoma - surgery Glaucoma and intraocular pressure Humans Infant Infant, Newborn Intraocular Pressure - physiology Kaplan-Meier Estimate Male Medical sciences Miscellaneous Ophthalmology Postoperative Complications Retrospective Studies Trabeculectomy - methods Treatment Outcome Glaucoma Human Protozoa Congenital developmental glaucoma Trabeculotomy congenital glaucoma Birth Eye disease Glaucoma (eye) Ciliata Ophthalmology Child childhood glaucoma
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Summary:	To determine the efficacy and safety of trabeculotomy in congenital glaucoma patients operated on within first 3 months of birth. A total of 36 eyes of 24 patients with congenital glaucoma, who underwent primary trabeculotomy within first 3 months of birth were included. Preoperative and postoperative intraocular pressures (IOP), corneal clarity, diameter, axial length, success rates, and complications were evaluated in this study. The mean follow-up was 38.38+/-11.77 months (range 12-48 months). Mean IOP was 33.16+/-7.28 mmHg (range 23-50 mmHg) preoperatively. At the final follow-up visit, the mean IOP was 21.41+/-7.34 mmHg (range 8-38 mmHg). Pre-and postoperative IOP differences were statistically significant at all examination periods (P<0.001). A12-, 24-, and 36-month success rates were 92, 82, and 74%, respectively. Survival analysis regarding to gender, preoperative corneal diameter and consaguinity were not statistically significant. Only preoperative axial length was a statistically significant parameter (P=0.024) for success. Postoperatively normal corneal clarity was achieved in 29 eyes (80.5%). The main complications were shallow anterior chamber in one (4.2%) eye and detachment of Descement's membrane in two (8.4%) eyes. Primary trabeculotomy is a safe and effective procedure for congenital glaucoma patients when operated within 3 months of birth. It has a favourable IOP control and a low rate of complications in three year period.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0950-222X 1476-5454
DOI:	10.1038/sj.eye.6702223