Search Results - "SUTTON, K. G"

Gabapentin inhibits high‐threshold calcium channel currents in cultured rat dorsal root ganglion neurones by Sutton, K G, Martin, D J, Pinnock, R D, Lee, K, Scott, R H

“…This study examined the action of gabapentin (gabapentin,1‐(aminomethyl) cyclohexane acetic acid (Neurontin®)) on voltage‐gated calcium (Ca2+) channel influx…”
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Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression by MARTIN, D. J, MCCLELLAND, D, HERD, M. B, SUTTON, K. G, HALL, M. D, LEE, K, PINNOCK, R. D, SCOTT, R. H

“…We have used the whole cell patch clamp method and fura-2 fluorescence imaging to study the actions of gabapentin (1-(aminoethyl) cyclohexane acetic acid) on…”
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Differential Inhibition of T-Type Calcium Channels by Neuroleptics by Santi, Celia M, Cayabyab, Francisco S, Sutton, Kathy G, McRory, John E, Mezeyova, Janette, Hamming, Kevin S, Parker, David, Stea, Anthony, Snutch, Terrance P

“…T-type calcium channels play critical roles in cellular excitability and have been implicated in the pathogenesis of a variety of neurological disorders…”
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Characterization of Ca2+ channel currents in cultured rat cerebellar granule neurones by Pearson, H A, Sutton, K G, Scott, R H, Dolphin, A C

“…1. High-threshold voltage-gated calcium channel currents (IBa) were studied in cultured rat cerebellar granule neurones using the whole-cell patch clamp…”
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Interactions of polyamines with neuronal ion channels by Scott, R H, Sutton, K G, Dolphin, A C

“…Polyamines, a group of aliphatic amines, exert selective and complex actions on a variety of ion channels. Polyamines are found endogenously, as normal…”
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Molecular and Functional Characterization of a Family of Rat Brain T-type Calcium Channels by McRory, John E., Santi, Celia M., Hamming, Kevin S.C., Mezeyova, Janette, Sutton, Kathy G., Baillie, David L., Stea, Anthony, Snutch, Terrance P.

“…Voltage-gated calcium channels represent a heterogenous family of calcium-selective channels that can be distinguished by their molecular,…”
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P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A by Snutch, Terrance P, Sutton, Kathy G, McRory, John E, Guthrie, Heather, Murphy, Timothy H

“…Spatial and temporal changes in intracellular calcium concentrations are critical for controlling gene expression in neurons. In many neurons,…”
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Modulation of neuronal Ca(2+)-dependent currents by neurotransmitters, G-proteins and toxins by Scott, R H, Currie, K P, Sutton, K G, Dolphin, A C

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The Sanitary Administration of Belfast in the Mid-1990s by LAMONT, J. R., McMANUS, E. W., SUTTON, G. K.

“…The paper presented in 1898 by F. W. Lockwood (a) provided a detailed description of the many and varied factors contributing to the health and welfare of the…”
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Gabapentin: A novel analgesic targeting voltage-gated calcium channels by Sutton, Kathy G., Snutch, Terrance P.

“…Given their vital roles in mediating neuronal excitability, it is not surprising that voltage‐gated calcium channels have been implicated in contributing to…”
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Aspects of calcium-activated chloride currents: A neuronal perspective by Scott, Roderick H, Sutton, Kathy G, Griffin, Andrew, Stapleton, Simon R, Currie, Kevin P.M

“…Ca 2+-activated Cl −channels are expressed in a variety of cell types, including central and peripheral neurones. These channels are activated by a rise in…”
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Inhibition of neuronal calcium channels by a novel peptide spider toxin, DW13.3 by Sutton, K G, Siok, C, Stea, A, Zamponi, G W, Heck, S D, Volkmann, R A, Ahlijanian, M K, Snutch, T P

“…Peptide toxins have proved to be useful agents, both in discriminating between different components of native calcium channel currents and in the molecular…”
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Inhibitory actions of synthesised polyamine spider toxins and their analogues on Ca2+-activated Cl- currents recorded from cultured DRG neurones from neonatal rats by Sutton, K G, Stapleton, S R, Scott, R H

“…The whole cell variant of the patch clamp technique was used to investigate the actions of polyamine spider toxins and their analogues on high…”
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Ca2+ currents in cerebellar granule neurones: role of internal Mg2+ in altering characteristics and antagonist effects by Pearson, H A, Sutton, K G, Scott, R H, Dolphin, A C

“…Using the whole-cell patch-clamp technique, Ca2+ channel currents were measured in cultured rat cerebellar granule neurones in the presence of 10 mM Ba2+. Two…”
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Earthquake swarm associated with volcanic eruption, CuraCoa Reef Area, Northern Tonga, July 1973 by S. J. GIBOWICZ, J. H. LATTER, G. K. SUTTON

“…A submarine volcanic eruption near Curagoa Reef, first observed on 12 J u l y 1973 (U.T.) f r om Tafalii Island, northern Tonga, was associated with an e a r t…”
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Inhibitory Actions of Synthesised Polyamine Spider Toxins and Their Analogues on Neuronal Voltage-Activated Calcium Currents by Sutton, Kathy G, Stapleton, Simon R, Timms, Graham, Gilmore, Jeremy, Brust, Paul F, Bleakman, David, Scott, Roderick H

“…The whole cell variant of the patch-clamp technique was used to investigate the actions of polyamine spider toxins and their analogues on high…”
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Voltage-dependent calcium channels — beyond dihydropyridine antagonists by Snutch, Terrance P, Sutton, Kathy G, Zamponi, Gerald W

“…The blockade of L-type calcium channels by dihydropyridines, phenylalkylamines and benzothiazepines has been well described and forms the basis of a…”
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P/Q-type calcium channels mediate the activity-dependent feedback of syntaxin-1A by SUTTON, K. G, MCRORY, J. E, GUTHRIE, H, MURPHY, T. H, SNUTOH, T. P

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Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin by Seabrook, Guy R, Sutton, Kathy G, Jarolimek, Wolfgang, Hollingworth, Gregory J, Teague, Simon, Webb, Janine, Clark, Natalie, Boyce, Susan, Kerby, Julie, Ali, Zahid, Chou, Margaret, Middleton, Richard, Kaczorowski, Gregory, Jones, A Brian

“…We have synthesized iodinated resiniferatoxin bearing a 4-hydroxy-5-iodo-3-methoxyphenylacetate ester (I-RTX) and have characterized its activity on rat and…”
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Inhibitory actions of synthesised polyamine spider toxins and their analogues on Ca super(2+)-activated Cl super(-) currents recorded from cultured DRG neurones from neonatal rats by Sutton, K G, Stapleton, SR, Scott, R H

“…The whole cell variant of the patch clamp technique was used to investigate the actions Ca super(2+) currents and Ca super(2+)-activated Cl super(-) currents…”
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