Search Results - "SUTFIN, T"
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Raising High-Density Lipoprotein in Humans Through Inhibition of Cholesteryl Ester Transfer Protein: An Initial Multidose Study of Torcetrapib
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2004)“…OBJECTIVE—The ability of the potent cholesteryl ester transfer protein (CETP) inhibitor torcetrapib (CP-529,414) to raise high-density lipoprotein cholesterol…”
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2
Comparative efficacy of a once-daily controlled-release formulation of glipizide and immediate-release glipizide in patients with NIDDM
Published in Diabetes care (01-12-1994)“…Comparative efficacy of a once-daily controlled-release formulation of glipizide and immediate-release glipizide in patients with NIDDM. M Berelowitz , C…”
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3
Stereoselective interaction of omeprazole with warfarin in healthy men
Published in Therapeutic drug monitoring (1989)“…The effect of concomitant treatment with omeprazole (20 mg/day) on the plasma concentration and anticoagulation effect of warfarin was studied in 21 young…”
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4
Contribution of the intestine to the first-pass metabolism of felodipine in the rat
Published in The Journal of pharmacology and experimental therapeutics (01-08-1989)“…The systemic availability of intraduodenally (i.d.) administered felodipine in the rat is about 10%. The purpose of this study was to determine to what extent…”
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Biliary secretion of felodipine metabolites in man after intravenous [14C]felodipine
Published in European journal of clinical pharmacology (01-01-1990)“…The biliary secretion of [14C]felodipine in 4 healthy human subjects was studied by use of the multiple marker dilution principle with double lumen tubes…”
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6
The effect of felodipine on bile flow in pentobarbital anaesthetized rats and conscious rats receiving bile salt supplementation
Published in European journal of drug metabolism and pharmacokinetics (01-10-1992)“…Felodipine, a vasoselective dihydropyridine calcium antagonist, has been given i.v. (0.2 mumol/kg) to anaesthetized and conscious male rats. There was no…”
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7
Liquid-chromatographic determination of eight tri- and tetracyclic antidepressants and their major active metabolites
Published in Clinical chemistry (Baltimore, Md.) (01-03-1984)“…A "high-performance" liquid-chromatographic method is presented for monitoring the therapeutic concentrations, in plasma, of eight tri- and tetracyclic…”
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8
Multiple-dose pharmacokinetics of imipramine and its major active and conjugated metabolites in depressed patients
Published in Journal of clinical psychopharmacology (01-02-1988)“…Imipramine (IMI) and its active metabolites, desipramine (DMI), 2-hydroxyimipramine (2-OH-IMI), and 2-hydroxydesipramine (2-OH-DMI), were assayed by high…”
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9
Effects of biliary excretion on the disposition of felodipine and metabolites in the rat
Published in Xenobiotica (1987)“…1. After i.v. and intraduodenal administration of 3H-felodipine to rats, approx. 50% of the dose was excreted in bile in the first 6 h. Total urinary and…”
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10
The analysis and disposition of imipramine and its active metabolites in man
Published in Psychopharmacologia (01-01-1984)“…Single oral and intramuscular (i.m.) doses of imipramine (IMI) were administered to four normal males. Serum and urine concentrations of IMI, desipramine (DMI)…”
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11
Early detection of aminoglycoside nephrotoxicity with urinary beta-2-microglobulin
Published in Journal of medicine (1978)“…We used a radioimmunoassay to evaluate the changes in the urinary excretion of beta2-microglobulin (beta2M) in 21 patients receiving aminoglycosides for…”
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12
High-performance liquid chromatographic assay for imipramine, desipramine, and their 2-hydroxylated metabolites
Published in Journal of pharmaceutical sciences (01-06-1979)“…High-performance liquid chromatographic method is presented for the simultaneous determination of imipramine, desipramine, and their 2-hydroxylated metabolites…”
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13
Pharmacokinetics and Pharmacodynamics of Extended-Release Glipizide GITS Compared with Immediate-Release Glipizide in Patients with Type II Diabetes Mellitus
Published in Journal of clinical pharmacology (01-06-2002)“…This study was designed to compare the pharmacokinetic and short‐term pharmacodynamic profile of extended‐release glipizide GITS (Glucotrol XL®) given in a…”
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14
Active metabolites of imipramine and desipramine in man
Published in Clinical pharmacology and therapeutics (01-03-1982)“…Active hydroxy metabolites of imipramine (IMI) and desipramine (DMI) have been quantified in plasma and cerebrospinal fluid (CSF) from patients at…”
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15
Excessive plasma concentration of tricyclic antidepressants resulting from usual doses: a report of six cases
Published in The journal of clinical psychiatry (01-04-1981)“…Six patients are described who achieved very high plasma concentrations of imipramine and desipramine during chronic therapy with usual doses. Side effects…”
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