Search Results - "SUSUMU, Nobuyuki"

Factors affecting pregnancy outcomes in young women treated with fertility-preserving therapy for well-differentiated endometrial cancer or atypical endometrial hyperplasia by Inoue, Osamu, Hamatani, Toshio, Susumu, Nobuyuki, Yamagami, Wataru, Ogawa, Seiji, Takemoto, Takashi, Hirasawa, Akira, Banno, Kouji, Kuji, Naoaki, Tanaka, Mamoru, Aoki, Daisuke

“…Patients hoping to preserve their fertility receive conservative treatment with high-dose medroxyprogesterone acetate (MPA) for well-differentiated…”
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Intratumoral CD8+ Lymphocyte Infiltration as a Prognostic Factor and Its Relationship With Cyclooxygenase 2 Expression and Microsatellite Instability in Endometrial Cancer by Suemori, Tomohiro, Susumu, Nobuyuki, Iwata, Takashi, Banno, Kouji, Yamagami, Wataru, Hirasawa, Akira, Sugano, Kokichi, Matsumoto, Eri, Aoki, Daisuke

“…Microsatellite instability (MSI) is caused by a defective DNA mismatch repair system. Colorectal cancer in MSI-positive patients is characterized by an…”
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ADAM9 is over‐expressed in human ovarian clear cell carcinomas and suppresses cisplatin‐induced cell death by Ueno, Mari, Shiomi, Takayuki, Mochizuki, Satsuki, Chijiiwa, Miyuki, Shimoda, Masayuki, Kanai, Yae, Kataoka, Fumio, Hirasawa, Akira, Susumu, Nobuyuki, Aoki, Daisuke, Okada, Yasunori

“…ADAMs (a disintegrin and metalloproteinases) are involved in various biological events such as cell adhesion, migration and invasion, membrane protein shedding…”
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Immunofluorescence-detected infiltration of CD4+FOXP3+ regulatory T cells is relevant to the prognosis of patients with endometrial cancer by Yamagami, Wataru, Susumu, Nobuyuki, Tanaka, Hideo, Hirasawa, Akira, Banno, Kouji, Suzuki, Nao, Tsuda, Hiroshi, Tsukazaki, Katsumi, Aoki, Daisuke

“…Host antitumor immune responses are associated with many types of immune cells and soluble components. In particular, CD8 cytotoxic T lymphocytes (CTLs) play a…”
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Phase II Evaluation of Paclitaxel and Carboplatin in the Treatment of Carcinosarcoma of the Uterus: A Gynecologic Oncology Group Study by POWELL, Matthew A, FILIACI, Virginia L, ROSE, Peter G, MANNEL, Robert S, HANJANI, Parviz, DEGEEST, Koen, MILLER, Brigitte E, SUSUMU, Nobuyuki, UELAND, Frederick R

“…Platinum and taxane compounds have demonstrated activity in uterine carcinosarcoma (malignant mixed Mullerian tumor). Ifosfamide plus paclitaxel is the regimen…”
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A phase II trial evaluating the efficacy and safety of repeated high dose medroxyprogesterone acetate (MPA) therapy for patients with recurrent early-stage endometrial cancer or atypical endometrial hyperplasia: Japanese Gynecologic Oncology Group study (JGOG2051/KGOG2031, REMPA trial) by Sakai, Kensuke, Yamagami, Wataru, Sato, Yasunori, Susumu, Nobuyuki, Yokoyama, Yoshihito, Takehara, Kazuhiro, Mandai, Masaki, Okamoto, Aikou

“…Fertility preserving therapy using medroxyprogesterone acetate (MPA) is an important option for young patients with endometrial cancer or atypical endometrial…”
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Is repeated high-dose medroxyprogesterone acetate (MPA) therapy permissible for patients with early stage endometrial cancer or atypical endometrial hyperplasia who desire preserving fertility? by Yamagami, Wataru, Susumu, Nobuyuki, Makabe, Takeshi, Sakai, Kensuke, Nomura, Hiroyuki, Kataoka, Fumio, Hirasawa, Akira, Banno, Kouji, Aoki, Daisuke

“…Reports on the repeated administration of medroxyprogesterone acetate (MPA) for intrauterine recurrence after fertility-preserving therapy for atypical…”
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Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary by Okamoto, Aikou, Glasspool, Rosalind M, Mabuchi, Seiji, Matsumura, Noriomi, Nomura, Hiroyuki, Itamochi, Hiroaki, Takano, Masashi, Takano, Tadao, Susumu, Nobuyuki, Aoki, Daisuke, Konishi, Ikuo, Covens, Alan, Ledermann, Jonathan, Mezzanzanica, Delia, Mezzazanica, Delia, Steer, Christopher, Millan, David, McNeish, Iain A, Pfisterer, Jacobus, Kang, Sokbom, Gladieff, Laurence, Bryce, Jane, Oza, Amit

“…Clear cell carcinoma of the ovary (CCC) is a histologic subtype of epithelial ovarian cancer with a distinct clinical behavior. There are marked geographic…”
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Survey of the clinical practice pattern of using sentinel lymph node biopsy in patients with gynecological cancers in Japan: the Japan Society of Gynecologic Oncology study by Togami, Shinichi, Kobayashi, Hiroaki, Niikura, Hitoshi, Shimada, Muneaki, Susumu, Nobuyuki, Tanaka, Tomohito, Terai, Yoshito, Nagai, Tomoyuki, Baba, Tsukasa, Yahata, Hideaki, Yamagami, Wataru, Yamaguchi, Ken, Yamashita, Tsuyoshi, Yaegashi, Nobuo, Katabuchi, Hidetaka, Aoki, Daisuke

“…Background Sentinel lymph node (SN) biopsy is essential for evaluating survival and minimal treatment-related morbidity associated with cervical, endometrial,…”
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MicroRNAs in endometrial cancer by Banno, Kouji, Yanokura, Megumi, Kisu, Iori, Yamagami, Wataru, Susumu, Nobuyuki, Aoki, Daisuke

“…MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) of approximately 22 bp that induce RNA interference with a complementary messenger RNA (mRNA)…”
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Identification of a novel uterine leiomyoma GWAS locus in a Japanese population by Sakai, Kensuke, Tanikawa, Chizu, Hirasawa, Akira, Chiyoda, Tatsuyuki, Yamagami, Wataru, Kataoka, Fumio, Susumu, Nobuyuki, Terao, Chikashi, Kamatani, Yoichiro, Takahashi, Atsushi, Momozawa, Yukihide, Hirata, Makoto, Kubo, Michiaki, Fuse, Nobuo, Takai-Igarashi, Takako, Shimizu, Atsushi, Fukushima, Akimune, Kadota, Aya, Arisawa, Kokichi, Ikezaki, Hiroaki, Wakai, Kenji, Yamaji, Taiki, Sawada, Norie, Iwasaki, Motoki, Tsugane, Shoichiro, Aoki, Daisuke, Matsuda, Koichi

“…Uterine leiomyoma is one of the most common gynaecologic benign tumours, but its genetic basis remains largely unknown. Six previous GWAS identified 33 genetic…”
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Clinicopathologic analysis with immunohistochemistry for DNA mismatch repair protein expression in synchronous primary endometrial and ovarian cancers by Kobayashi, Yusuke, Nakamura, Kanako, Nomura, Hiroyuki, Banno, Kouji, Irie, Haruko, Adachi, Masataka, Iida, Miho, Umene, Kiyoko, Nogami, Yuya, Masuda, Kenta, Kisu, Iori, Ueki, Arisa, Yamagami, Wataru, Kataoka, Fumio, Hirasawa, Akira, Tominaga, Eiichiro, Susumu, Nobuyuki, Aoki, Daisuke

“…Synchronous primary endometrial and ovarian cancers have been an important topic in clinical medicine because it is sometimes difficult to distinguish whether…”
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Prognostic factors in patients with uterine carcinosarcoma: a multi-institutional retrospective study from the Japanese Gynecologic Oncology Group by Harano, Kenichi, Hirakawa, Akihiro, Yunokawa, Mayu, Nakamura, Toshiaki, Satoh, Toyomi, Nishikawa, Tadaaki, Aoki, Daisuke, Ito, Kimihiko, Ito, Kiyoshi, Nakanishi, Toru, Susumu, Nobuyuki, Takehara, Kazuhiro, Watanabe, Yoh, Watari, Hidemichi, Saito, Toshiaki

“…Background Uterine carcinosarcomas (UCSs) are rare and aggressive tumors. The prognostic factors are not sufficiently known. Methods We performed a…”
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Clinical implications of next‐generation sequencing‐based panel tests for malignant ovarian tumors by Saotome, Keiko, Chiyoda, Tatsuyuki, Aimono, Eriko, Nakamura, Kohei, Tanishima, Shigeki, Nohara, Sachio, Okada, Chihiro, Hayashi, Hideyuki, Kuroda, Yuka, Nomura, Hiroyuki, Susumu, Nobuyuki, Iwata, Takashi, Yamagami, Wataru, Kataoka, Fumio, Nishihara, Hiroshi, Aoki, Daisuke

“…Precision medicine based on cancer genomics is being applied in clinical practice. However, patients do not always derive benefits from genomic testing. Here,…”
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Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles by Hirano, Takuro, Arai, Eri, Fujimoto, Mao, Nakayama, Yuji, Tian, Ying, Ito, Nanako, Makabe, Takeshi, Yamagami, Wataru, Susumu, Nobuyuki, Aoki, Daisuke, Kanai, Yae

“…OBJECTIVEThe aim of this study was to establish criteria that would indicate whether fertility preservation therapy would likely be safe for patients aged 40…”
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Polymorphisms in the UGT1A1 gene predict adverse effects of irinotecan in the treatment of gynecologic cancer in Japanese patients by Hirasawa, Akira, Zama, Takeru, Akahane, Tomoko, Nomura, Hiroyuki, Kataoka, Fumio, Saito, Koichiro, Okubo, Keisuke, Tominaga, Eiichiro, Makita, Kazuya, Susumu, Nobuyuki, Kosaki, Kenjiro, Tanigawara, Yusuke, Aoki, Daisuke

“…Irinotecan is a key chemotherapeutic drug used to treat many tumors, including cervical and ovarian cancers; however, irinotecan can cause toxicity,…”
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Gynecologic Cancer InterGroup (GCIG) consensus review for uterine serous carcinoma by Sagae, Satoru, Susumu, Nobuyuki, Viswanathan, Akila N, Aoki, Daisuke, Backes, Floor J, Provencher, Diane M, Vaughan, Michelle, Creutzberg, Carien L, Kurzeder, Christian, Kristensen, Gunnar, Lee, Chulmin, Kurtz, Jean-Emmanuel, Glasspool, Rosalind M, Small, Jr, William

“…Uterine serous carcinoma (USC) represents a rare and aggressive histologic subtype of endometrial cancer, associated with a poor prognosis. This article…”
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Preoperative differential diagnosis of minimal deviation adenocarcinoma and lobular endocervical glandular hyperplasia of the uterine cervix: a multicenter study of clinicopathology and magnetic resonance imaging findings by Takatsu, Akiko, Shiozawa, Tanri, Miyamoto, Tsutomu, Kurosawa, Kazuko, Kashima, Hiroyasu, Yamada, Tomoko, Kaku, Tsunehisa, Mikami, Yoshiki, Kiyokawa, Takako, Tsuda, Hitoshi, Ishii, Keiko, Togashi, Kaori, Koyama, Takashi, Fujinaga, Yasunari, Kadoya, Masumi, Hashi, Akihiko, Susumu, Nobuyuki, Konishi, Ikuo

“…To clarify the preoperative differential diagnosis and management of minimal deviation adenocarcinoma (MDA) and lobular endocervical glandular hyperplasia…”
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A Comparison of Dye Versus Fluorescence Methods for Sentinel Lymph Node Mapping in Endometrial Cancer by Yamagami, Wataru, Susumu, Nobuyuki, Kataoka, Fumio, Makabe, Takeshi, Sakai, Kensuke, Ninomiya, Tomomi, Wada, Michiko, Nomura, Hiroyuki, Hirasawa, Akira, Banno, Kouji, Nakahara, Tadaki, Kameyama, Kaori, Aoki, Daisuke

“…Sentinel nodes (SNs) have been observed in several reports from Japan and overseas in cases with endometrial cancer; however, no consensus has been reached…”
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Elevated preoperative neutrophil : lymphocyte ratio as a preoperative indicator of mature cystic teratoma with malignant transformation by Nanki, Yoshiko, Chiyoda, Tatsuyuki, Kataoka, Fumio, Nomura, Hiroyuki, Nakadaira, Naoki, Iwasa, Naomi, Hashimoto, Shiho, Arima, Hirokazu, Susumu, Nobuyuki, Aoki, Daisuke

“…Aim To examine the usefulness of the neutrophil : lymphocyte (N/L) ratio as a cost‐effective and simple diagnostic marker of mature cystic teratoma (MCT) with…”
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