Search Results - "SUSCOVICH, T"

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies by Sips, M, Krykbaeva, M, Diefenbach, T J, Ghebremichael, M, Bowman, B A, Dugast, A-S, Boesch, A W, Streeck, H, Kwon, D S, Ackerman, M E, Suscovich, T J, Brouckaert, P, Schacker, T W, Alter, G

“…Although the development of a fully protective HIV vaccine is the ultimate goal of HIV research, to date only one HIV vaccine trial, the RV144, has…”
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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16 by Gunn, B M, Schneider, J R, Shansab, M, Bastian, A R, Fahrbach, K M, Smith, A D, Mahan, A E, Karim, M M, Licht, A F, Zvonar, I, Tedesco, J, Anderson, M R, Chapel, A, Suscovich, T J, Malaspina, D C, Streeck, H, Walker, B D, Kim, A, Lauer, G, Altfeld, M, Pillai, S, Szleifer, I, Kelleher, N L, Kiser, P F, Hope, T J, Alter, G

“…Transmission of HIV across mucosal barriers accounts for the majority of HIV infections worldwide. Thus, efforts aimed at enhancing protective immunity at…”
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Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection by DRAENERT, R, VERRILL, C. L, ADDO, M. M, WALKER, B. D, TANG, Y, ALLEN, T. M, WURCEL, A. G, BOCZANOWSKI, M, LECHNER, A, KIM, A. Y, SUSCOVICH, T, BROWN, N. V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impaired CTL Recognition of Cells Latently Infected with Kaposi's Sarcoma-Associated Herpes Virus by Brander, Christian, Suscovich, Todd, Lee, Yun, Nguyen, Phuong Thi, O'Connor, Paula, Seebach, Joerg, Jones, Norman G, van Gorder, Mark, Walker, Bruce D, Scadden, David T

“…Kaposi's sarcoma-associated herpes virus (KSHV) is a recently identified human gamma2-herpesvirus associated with Kaposi's sarcoma, primary effusion lymphoma,…”
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Differential Targeting and Shifts in the Immunodominance of Epstein‐Barr Virus–Specific CD8 and CD4 T Cell Responses during Acute and Persistent Infection by Woodberry, Tonia , Suscovich, Todd J. , Henry, Leah M. , Davis, Jennifer K. , Frahm, Nicole , Walker, Bruce D. , Scadden, David T. , Wang, Frederick , Brander, Christian 

“…The evolution of Epstein‐Barr virus (EBV)–specific T cell responses that occurs during the acute and persistent stages of infection remains poorly…”
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Determination of Intermediate Biomarker Expression Levels by Quantitative Reverse Transcription-Polymerase Chain Reaction in Oral Mucosa of Cancer Patients Treated with Liarozole by QING ZENG, SMITH, D. C, SUSCOVICH, T. J, GOODING, W. E, TRUMP, D. L, GRANDIS, J. R

“…Liarozole is a 1-substituted imidazole derivative that inhibits cytochrome P450 activity and increases endogenous plasma concentrations of retinoid acid (RA)…”
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Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection by Sciaranghella, Gaia, Tong, Neath, Mahan, Alison E, Suscovich, Todd J, Alter, Galit

“…To define the impact of chronic viremia and associated immune activation on B-cell exhaustion in HIV infection. Progressive HIV infection is marked by B-cell…”
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Tissue distribution of liposome-mediated epidermal growth factor receptor antisense gene therapy by Thomas, Sufi M, Zeng, Qing, Dyer, Kevin F, Suscovich, Todd J, Kanter, Peter M, Whalen, Janey D, Watkins, Simon F, Grandis, Jennifer Rubin

“…Despite the widespread use of liposome-mediated gene transfer in cancer therapy protocols, little is known about the tissue distribution of intralesionally…”
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Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women by Collier, A.Y., McMahan, K., Yu, J., Tostanoski, L.H., Aguayo, R., Ansel, J., Chandrashekar, A., Patel, S., Apraku Bondzie, E., Sellers, D., Barrett, J., Sanborn, O., Wan, H., Chang, A., Anioke, T., Nkolola, J., Bradshaw, C., Jacob-Dolan, C., Feldman, J., Gebre, M., Borducchi, E.N., Liu, J., Schmidt, A.G., Suscovich, T., Linde, C., Alter, G., Hacker, M.R., Barouch, D.H.

“…(JAMA. 2021;325:2370–2380. doi-10.1001/jama2021.7563) Pregnant women are at a greater risk of severe complications from symptomatic COVID-19, including ICU…”
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Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands by MEIER, Angela, BAGCHI, Aranya, ALTFELD, Marcus, SIDHU, Harlyn K, ALTER, Galit, SUSCOVICH, Todd J, KAVANAGH, Daniel G, STREECK, Hendrik, BROCKMAN, Mark A, LEGALL, Sylvie, HELLMAN, Judith

“…Increased PD-L1 expression has been reported in HIV-1-infected individuals, but the mechanisms leading to PD-L1 upregulation remain to be elucidated. Here we…”
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Low perforin and elevated SHIP-1 expression is associated with functional anergy of natural killer cells in chronic HIV-1 infection by ALTER, Galit, SUSCOVICH, Todd J, KLEYMAN, Marianna, TEIGEN, Nickolas, STREECK, Hendrik, TAUHEED ZAMAN, M, MEIER, Angela, ALTFELD, Marcus

“…Natural killer (NK) cells are critical for the first-line defense in infection. Treated viremic HIV-1 infection is associated with the expansion of an anergic…”
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Impact of Kaposi Sarcoma–Associated Herpesvirus (KSHV) Burden and HIV Coinfection on the Detection of T Cell Responses to KSHV ORF73 and ORF65 Proteins by Woodberry, Tonia, Suscovich, Todd J., Henry, Leah M., Martin, Jeff N., Dollard, Sheila, O’Connor, Paula G., Davis, Jennifer K., Osmond, Dennis, Lee, Tzong-Hae, Kedes, Dean H., Khatri, Ashok, Lee, Jeannette, Walker, Bruce D., Scadden, David T., Brander, Christian

“…Cellular immune responses to Kaposi sarcoma–associated herpesvirus (KSHV), the etiological agent of KS and several other malignancies, are incompletely…”
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Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection by Alter, Galit, Teigen, Nickolas, Davis, Benjamin T., Addo, Marylyn M., Suscovich, Todd J., Waring, Michael T., Streeck, Hendrik, Johnston, Mary N., Staller, Kyle D., Zaman, M. Tauheed, Yu, Xu G., Lichterfeld, Mathias, Basgoz, Nesli, Rosenberg, Eric S., Altfeld, Marcus

“…Natural killer (NK) cells are critical in the first-line defense against viral infections. Chronic HIV-1 infection leads to a perturbation in the NK cell…”
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Definition of an Optimal Cytotoxic T Lymphocyte Epitope in the Latently Expressed Kaposi's Sarcoma-Associated Herpesvirus Kaposin Protein by Brander, Christian, O’Connor, Paula, Suscovich, Todd, Jones, Norman G., Lee, Yun, Kedes, Dean, Ganem, Don, Martin, Jeff, Osmond, Dennis, Southwood, Scott, Sette, Alessandro, Walker, Bruce D., Scadden, David T.

“…Cytotoxic T lymphocytes (CTL) recognize and kill virus-infected cells and contribute to immunologic control of viral replication. For many herpesviruses (e.g.,…”
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Heat Shock Protein-Mediated Cross-Presentation of Exogenous HIV Antigen on HLA Class I and Class II by SenGupta, Devi, Norris, Philip J, Suscovich, Todd J, Hassan-Zahraee, Mina, Moffett, Howell F, Trocha, Alicja, Draenert, Rika, Goulder, Philip J. R, Binder, Robert J, Levey, Daniel L, Walker, Bruce D, Srivastava, Pramod K, Brander, Christian

“…Strong CD4(+) and CD8(+) T cell responses are considered important immune components for controlling HIV infection, and their priming may be central to an…”
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Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot" by Bihl, Florian K, Loggi, Elisabetta, Chisholm, 3rd, John V, Hewitt, Hannah S, Henry, Leah M, Linde, Caitlyn, Suscovich, Todd J, Wong, Johnson T, Frahm, Nicole, Andreone, Pietro, Brander, Christian

“…The assessment of cellular anti-viral immunity is often hampered by the limited availability of adequate samples, especially when attempting simultaneous,…”
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Defective Immune Function of Primary Effusion Lymphoma Cells is Associated with Distinct KSHV Gene Expression Profiles by Suscovich, Todd J, Paulose-Murphy, Mini, Harlow, Jason D, Chen, Yidong, Thomas, Seddon Y, Mellott, Tiffany J, Walker, Bruce D, Scadden, David T, Zeichner, Steven, Brander, Christian

“…Primary effusion lymphomas (PEL) are uniformly infected with Kaposi's sarcoma-associated herpesvirus (KSHV), and thus likely present both tumor and viral…”
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