Search Results - "SURABHI, Rama M"
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Small Interfering RNAs Directed against β-Catenin Inhibit the in Vitro and in Vivo Growth of Colon Cancer Cells
Published in Clinical cancer research (01-04-2003)“…The β-catenin and APC genes are key components of the Wnt signaling pathway. Mutation of these genes results in increased levels of the β-catenin protein,…”
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RNA Interference Directed against Viral and Cellular Targets Inhibits Human Immunodeficiency Virus Type 1 Replication
Published in Journal of Virology (01-12-2002)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation Properties
Published in Molecular cell (01-04-2003)“…SPT5 and its binding partner SPT4 function in both positively and negatively regulating transcriptional elongation. The demonstration that SPT5 and RNA…”
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TAK1 is Critical for IκB Kinase-mediated Activation of the NF-κB Pathway
Published in Journal of molecular biology (07-02-2003)“…Cytokine treatment stimulates the IκB kinases, IKKα and IKKβ, which phosphorylate the IκB proteins, leading to their degradation and activation of NF-κB…”
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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway
Published in Journal of molecular biology (07-02-2003)“…Cytokine treatment stimulates the IkappaB kinases, IKKalpha and IKKbeta, which phosphorylate the IkappaB proteins, leading to their degradation and activation…”
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