Search Results - "SUNWOO, John B"
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The Immune Subtypes and Landscape of Squamous Cell Carcinoma
Published in Clinical cancer research (15-06-2019)“…To identify immune subtypes and investigate the immune landscape of squamous cell carcinomas (SCC), which share common etiology and histologic features. Based…”
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2
American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in Adults
Published in Thyroid (New York, N.Y.) (01-07-2018)“…Hypoparathyroidism (hypoPT) is the most common complication following bilateral thyroid operations. Thyroid surgeons must employ strategies for minimizing and…”
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3
Racial Disparities in 30‐day Readmissions after Surgery for Head and Neck Cancer
Published in The Laryngoscope (01-03-2024)“…Background Native Hawaiians and other Pacific Islanders (NHPI) patients with head and neck cancer are often aggregated with Asian individuals despite evidence…”
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Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment
Published in Proceedings of the National Academy of Sciences - PNAS (13-07-2021)“…Natural killer (NK) cells comprise one subset of the innate lymphoid cell (ILC) family. Despite reported antitumor functions of NK cells, their tangible…”
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5
NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma
Published in Scientific reports (06-12-2017)“…Chromatin modifying enzymes are frequently mutated in cancer, resulting in widespread epigenetic deregulation. Recent reports indicate that inactivating…”
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Emerging NK cell therapies for cancer and the promise of next generation engineering of iPSC-derived NK cells
Published in Journal for immunotherapy of cancer (01-05-2022)“…Adoptive cell therapy is a rapidly advancing approach to cancer immunotherapy that seeks to facilitate antitumor responses by introducing potent effector cells…”
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Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2013)“…The aryl hydrocarbon receptor (AhR) has become increasingly recognized for its role in the differentiation and activity of immune cell subsets; however, its…”
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8
Identification of human NK cells that are deficient for signaling adaptor FcRγ and specialized for antibody-dependent immune functions
Published in International immunology (01-12-2012)“…NK cells respond to tumor and virus-infected cells directly through several activation receptors, including natural cytotoxicity receptors, or indirectly…”
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9
Oral cavity cancer in young, non-smoking, and non-drinking patients: A contemporary review
Published in Critical reviews in oncology/hematology (01-10-2023)“…Oral squamous cell carcinoma (OSCC) in non-smoking and non-drinking (NSND) individuals appears to be distinct from the traditional head and neck squamous cell…”
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10
High-resolution positron emission microscopy of patient-derived tumor organoids
Published in Nature communications (07-10-2021)“…Tumor organoids offer new opportunities for translational cancer research, but unlike animal models, their broader use is hindered by the lack of clinically…”
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11
ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness
Published in Cancer research (Chicago, Ill.) (01-01-2012)“…Carcinogen-induced oral cavity squamous cell carcinoma (OSCC) incurs significant morbidity and mortality and constitutes a global health challenge. To gain…”
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12
Licensing of natural killer cells by host major histocompatibility complex class I molecules
Published in Nature (04-08-2005)“…Self versus non-self discrimination is a central theme in biology from plants to vertebrates, and is particularly relevant for lymphocytes that express…”
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13
Natural Killer Cells and Thyroid Diseases
Published in Endocrinology and metabolism (Seoul) (01-06-2019)“…Abnormal production of thyroid hormone is one of the common endocrine disorders, and thyroid hormone production declines with age. The aging process also…”
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14
AHR Regulates NK Cell Migration via ASB2-Mediated Ubiquitination of Filamin A
Published in Frontiers in immunology (24-02-2021)“…Natural killer (NK) cells are effector cells of the innate immune system involved in defense against virus-infected and transformed cells. The effector…”
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15
T cell-mediated curation and restructuring of tumor tissue coordinates an effective immune response
Published in Cell reports (Cambridge) (26-12-2023)“…Antigen-specific T cells traffic to, are influenced by, and create unique cellular microenvironments. Here we characterize these microenvironments over time…”
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Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence
Published in Cancer (01-04-2013)“…BACKGROUND: In head and neck cancer (HNC), 3‐month post‐treatment positron emission tomography (PET)/computed tomography (CT) reliably identifies…”
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17
PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma
Published in Otolaryngology-head and neck surgery (01-01-2019)“…Objective To characterize programmed death–ligand 1 (PD-L1) expression and tumor-infiltrating lymphocyte (TIL) positivity for locally aggressive or regionally…”
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18
Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer
Published in Genome medicine (17-11-2023)“…The prognosis for patients with head and neck cancer (HNC) is poor and has improved little in recent decades, partially due to lack of therapeutic options. To…”
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Immunotherapy for Head and Neck Squamous Cell Carcinoma
Published in Hematology/oncology clinics of North America (01-12-2015)“…Although head and neck squamous cell carcinoma has traditionally been considered to be a very immunosuppressive, or at least nonimmunogenic, tumor type, recent…”
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Humanized Mouse Models for the Advancement of Innate Lymphoid Cell-Based Cancer Immunotherapies
Published in Frontiers in immunology (22-04-2021)“…Innate lymphoid cells (ILCs) are a branch of the immune system that consists of diverse circulating and tissue-resident cells, which carry out functions…”
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