Search Results - "SUMAN LAAL"

Mycobacterium tuberculosis Primary Infection and Dissemination: A Critical Role for Alveolar Epithelial Cells by Ryndak, Michelle B, Laal, Suman

“…Globally, tuberculosis (TB) has reemerged as a major cause of morbidity and mortality, despite the use of the BCG vaccine and intensive attempts to improve…”
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Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis by Steingart, Karen R, Flores, Laura L, Dendukuri, Nandini, Schiller, Ian, Laal, Suman, Ramsay, Andrew, Hopewell, Philip C, Pai, Madhukar

“…Serological (antibody detection) tests for tuberculosis (TB) are widely used in developing countries. As part of a World Health Organization policy process, we…”
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Evaluation of immunodominant peptides of in vivo expressed mycobacterial antigens in an ELISA-based diagnostic assay for pulmonary tuberculosis by Sharma, Sumedha, Suri, Deepti, Aggarwal, Ashutosh N., Yadav, Rakesh, Sethi, Sunil, Laal, Suman, Verma, Indu

“…Non-sputum-based biomarker assay is urgently required as per WHO’s target product pipeline for diagnosis of tuberculosis. Therefore, the current study was…”
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Transcriptional profile of Mycobacterium tuberculosis replicating in type II alveolar epithelial cells by Ryndak, Michelle B, Singh, Krishna K, Peng, Zhengyu, Laal, Suman

“…Mycobacterium tuberculosis (M. tb) infection is initiated by the few bacilli inhaled into the alveolus. Studies in lungs of aerosol-infected mice provided…”
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Transcriptome analysis of mycobacteria in sputum samples of pulmonary tuberculosis patients by Sharma, Sumedha, Ryndak, Michelle B, Aggarwal, Ashutosh N, Yadav, Rakesh, Sethi, Sunil, Masih, Shet, Laal, Suman, Verma, Indu

“…Pulmonary tuberculosis, the disease caused by Mycobacterium tuberculosis, still retains a top rank among the deadliest communicable diseases. Sputum…”
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Association of Micronutrients with Tuberculosis Development in HIV Infected Patients by Banyal, Dinesh, Sharma, Sumedha, Ram, Anil Kumar, Kaur, Khushpreet, Jassal, Ravjit Singh, Attri, Savita, Sharma, Aman, Sharma, Kusum, Laal, Suman, Verma, Indu

“…Human immunodeficiency virus (HIV) infection associated with weakened immune system due to decreased CD4 T cell count favors development of tuberculosis…”
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Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review by Steingart, Karen R, Henry, Megan, Laal, Suman, Hopewell, Philip C, Ramsay, Andrew, Menzies, Dick, Cunningham, Jane, Weldingh, Karin, Pai, Madhukar

“…The global tuberculosis epidemic results in nearly 2 million deaths and 9 million new cases of the disease a year. The vast majority of tuberculosis patients…”
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Performance of Purified Antigens for Serodiagnosis of Pulmonary Tuberculosis: a Meta-Analysis by Steingart, Karen R, Dendukuri, Nandini, Henry, Megan, Schiller, Ian, Nahid, Payam, Hopewell, Philip C, Ramsay, Andrew, Pai, Madhukar, Laal, Suman

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Transcriptional Profile of Mycobacterium tuberculosis in an in vitro Model of Intraocular Tuberculosis by Abhishek, Sudhanshu, Saikia, Uma Nahar, Gupta, Amod, Bansal, Reema, Gupta, Vishali, Singh, Nirbhai, Laal, Suman, Verma, Indu

“…Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly…”
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LipC (Rv0220) Is an Immunogenic Cell Surface Esterase of Mycobacterium tuberculosis by Shen, Guomiao, Singh, Krishna, Chandra, Dinesh, Serveau-Avesque, Carole, Maurin, Damien, Canaan, Stéphane, Singla, Rupak, Behera, Digambar, Laal, Suman

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Transcriptional profiling of Mycobacterium tuberculosis replicating ex vivo in blood from HIV- and HIV+ subjects by Ryndak, Michelle B, Singh, Krishna K, Peng, Zhengyu, Zolla-Pazner, Susan, Li, Hualin, Meng, Lu, Laal, Suman

“…Hematogenous dissemination of Mycobacterium tuberculosis (M. tb) occurs during both primary and reactivated tuberculosis (TB). Although hematogenous…”
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Disease State Differentiation and Identification of Tuberculosis Biomarkers via Native Antigen Array Profiling by Sartain, Mark J, Slayden, Richard A, Singh, Krishna K, Laal, Suman, Belisle, John T

“…A critical element of tuberculosis control is early and sensitive diagnosis of infection and disease. Our laboratories recently showed that different stages of…”
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Development of a POC test for TB based on multiple immunodominant epitopes of M. tuberculosis specific cell-wall proteins by Gonzalez, Jesus M, Francis, Bryan, Burda, Sherri, Hess, Kaitlyn, Behera, Digamber, Gupta, Dheeraj, Agarwal, Ashutosh Nath, Verma, Indu, Verma, Ajoy, Myneedu, Vithal Prasad, Niedbala, Sam, Laal, Suman

“…The need for an accurate, rapid, simple and affordable point-of-care (POC) test for Tuberculosis (TB) that can be implemented in microscopy centers and other…”
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Mycobacterium tuberculosis malate synthase is a laminin‐binding adhesin by Kinhikar, Arvind G., Vargas, Diana, Li, Hualin, Mahaffey, Spencer B., Hinds, Laura, Belisle, John T., Laal, Suman

“…Summary Mycobacterium tuberculosis (M. tb) uses the glyoxalate bypass for intracellular survival in vivo. These studies provide evidence that the M. tb malate…”
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Peptide-Based Antibody Detection for Tuberculosis Diagnosis by Shen, Guomiao, Behera, Digambar, Bhalla, Manpreet, Nadas, Arthur, Laal, Suman

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Antibodies against Immunodominant Antigens of Mycobacterium tuberculosis in Subjects with Suspected Tuberculosis in the United States Compared by HIV Status by Achkar, Jacqueline M., Jenny-Avital, Elisabeth, Yu, Xian, Burger, Susanne, Leibert, Eric, Bilder, Patrick W., Almo, Steven C., Casadevall, Arturo, Laal, Suman

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Transcriptional profiling of Mycobacterium tuberculosis replicating in the human type II alveolar epithelial cell line, A549 by Ryndak, Michelle B., Singh, Krishna K., Peng, Zhengyu, Laal, Suman

“…Alveolar epithelial cells outnumber alveolar macrophages by ~500 fold and increasing evidence suggests that Mycobacterium tuberculosis may replicate…”
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Biomarkers for clinical and incipient tuberculosis: performance in a TB-endemic country by Wanchu, Ajay, Dong, Yuxin, Sethi, Sunil, Myneedu, V P, Nadas, Arthur, Liu, Zhentong, Belisle, John, Laal, Suman

“…Simple biomarkers are required to identify TB in both HIV(-)TB(+) and HIV(+)TB(+) patients. Earlier studies have identified the M. tuberculosis Malate Synthase…”
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Immunogenicity of the Mycobacterium tuberculosis PPE55 (Rv3347c) Protein during Incipient and Clinical Tuberculosis by Singh, Krishna K, Dong, Yuxin, Patibandla, Sai A, McMurray, David N, Arora, Vijay K, Laal, Suman

“…Clinical tuberculosis (TB), whether noncavitary or cavitary, is the late stage of a chronic disease process, since Mycobacterium tuberculosis is a slowly…”
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Antigens of Mycobacterium tuberculosis recognized by antibodies during incipient, subclinical tuberculosis by Singh, Krishna K, Dong, Yuxin, Belisle, John T, Harder, Jeffrey, Arora, Vijay K, Laal, Suman

“…Serum samples obtained from human immunodeficiency virus (HIV)-infected tuberculosis (TB) patients months prior to clinical TB were used to delineate the…”
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