Search Results - "SULLIVAN, P M"

A meta-review of stress, coping and interventions in dementia and dementia caregiving by Gilhooly, K J, Gilhooly, M L M, Sullivan, M P, McIntyre, A, Wilson, L, Harding, E, Woodbridge, R, Crutch, S

“…There has been a substantial number of systematic reviews of stress, coping and interventions for people with dementia and their caregivers. This paper…”
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Apolipoprotein E Allele-Dependent Pathogenesis: A Model for Age-Related Retinal Degeneration by Malek, G., Johnson, L. V., Mace, B. E., Saloupis, P., Schmechel, D. E., Rickman, D. W., Toth, C. A., Sullivan, P. M., Rickman, C. Bowes, Nathans, Jeremy

“…Age-related macular degeneration (AMD) is a late-onset, multifactorial, neurodegenerative disease of the retina and the leading cause of irreversible vision…”
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Reduced levels of human apoE4 protein in an animal model of cognitive impairment by Sullivan, P.M, Han, B, Liu, F, Mace, B.E, Ervin, J.F, Wu, S, Koger, D, Paul, S, Bales, K.R

“…Abstract The APOE4 allele is the most common genetic determinant for Alzheimer's disease (AD) in the developed world. APOE genotype specific differences in…”
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MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease by DICKERSON, B. C, GONCHAROVA, I, SULLIVAN, M. P, FORCHETTI, C, WILSON, R. S, BENNETT, D. A, BECKETT, L. A, DETOLEDO-MORRELL, L

“…With high resolution, quantitative magnetic resonance imaging (MRI) techniques, it is now possible to examine alterations in brain anatomy in vivo and to…”
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Use of the physical environment to support everyday activities for people with dementia: A systematic review by Woodbridge, R, Sullivan, MP, Harding, E, Crutch, S, Gilhooly, KJ, Gilhooly, MLM, McIntyre, A, Wilson, L

“…Difficulty with everyday activities is a key symptom and defining feature of dementia, relating to subjective reports of well-being and overall quality of…”
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Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2 by Klein, R.C, Mace, B.E, Moore, S.D, Sullivan, P.M

“…Abstract Inheritance of the APOE4 allele is a well established genetic risk factor linked to the development of late onset Alzheimer's disease. As the major…”
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Progress in understanding of inhibitory purinergic neuromuscular transmission in the gut by Goyal, R. K., Sullivan, M. P., Chaudhury, Arun

“…Recent studies with genetic deletion of P2Y1 receptor (P2Y1−/−) have clinched its role in enteric purinergic inhibitory neurotransmission and suggested that…”
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Influence of Western diet and APOE genotype on Alzheimer's disease risk by Sullivan, P.M.

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Marked regional differences of brain human apolipoprotein e expression in targeted replacement mice by Sullivan, P.M, Mace, B.E, Maeda, N, Schmechel, D.E

“…We used three human apolipoprotein (apo) E targeted replacement mouse lines, each expressing one of the three common human apoE isoforms to study the pattern…”
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An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer’s disease pathology following closed head injury: Evidence of pharmacogenomic interaction by Wang, H, Durham, L, Dawson, H, Song, P, Warner, D.S, Sullivan, P.M, Vitek, M.P, Laskowitz, D.T

“…Abstract Apolipoprotein E (apoE) modifies glial activation and the CNS inflammatory response in an isoform-specific manner. Peptides derived from the…”
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Vitreoretinal surgery after childhood ocular trauma by SHEARD, R. M, MIRESKANDARI, K, EZRA, E, SULLIVAN, P. M

“…In adults modern vitreoretinal surgery allows many traumatised eyes to be salvaged. However, one third of serious eye injuries occur in the paediatric age…”
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A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation by Hurt, Richard D, Sachs, David P.L, Glover, Penny N, Glover, Elbert D, Offord, Kenneth P, Johnston, J. Andrew, Dale, Lowell C, Khayrallah, Moise A, Schroeder, Darrell R, Sullivan, C. Rollynn, Sullivan, Pamela M, Croghan, Ivana T

“…Pharmacologic treatments such as nicotine-replacement therapy have been shown to help smokers stop smoking. Using a medication that does not contain nicotine,…”
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APOE genotype affects outcome in a murine model of sepsis : implications for a new treatment strategy by WANG, H, CHRISTENSEN, D. J, VITEK, M. P, SULLIVAN, P. M, LASKOWITZ, D. T

“…In this study, we assessed whether apolipoprotein E (APOE) polymorphism affects inflammatory responses and mortality in the caecal ligation and puncture model…”
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Cemented Rotating-Platform Total Knee Replacement : A Nine to Twelve-Year Follow-up Study by Callaghan, John J, Squire, Matt W, Goetz, Devon D, Sullivan, Patrick M, Johnston, Richard C

“…BackgroundAlthough the LCS (low contact stress) rotating-platform mobile-bearing knee replacement has been used extensively, there have been few intermediate…”
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Unicompartmental knee replacement. A minimum 15 year followup study by Squire, M W, Callaghan, J J, Goetz, D D, Sullivan, P M, Johnston, R C

“…One hundred forty Marmor cemented unicompartmental knee replacements were inserted in 103 patients between 1975 and 1982. Fifty-two patients were women and 51…”
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Inactivation of TMEM106A promotes lipopolysaccharide‐induced inflammation via the MAPK and NF‐κB signaling pathways in macrophages by Zhang, X., Feng, T., Zhou, X., Sullivan, P. M., Hu, F., Lou, Y., Yu, J., Feng, J., Liu, H., Chen, Y.

“…TMEM106A levels were increased in mouse and human monocytes/macrophages. Tmem106a deletion promotes the activation of macrophages and polarization towards M1…”
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Urodynamic characterization of nonobstructive voiding dysfunction in symptomatic elderly men by Ameda, K, Sullivan, M P, Bae, R J, Yalla, S V

“…The pathogenesis of lower urinary tract symptoms in men without bladder outlet obstruction has not been well characterized. Therefore, we defined the…”
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Towards a better understanding of patient perspectives of clinical teaching in ophthalmology by Ezra, D G, Salam, T, Sullivan, P M, Okhravi, N

“…Objective To investigate of the perspectives of ophthalmology patients involved in clinical teaching. Methods In all, 26 patients attending a revision course…”
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Stream-floodplain connectivity and fish assemblage diversity in the Champlain Valley, Vermont, U.S.A by Sullivan, S. M. P., Watzin, M. C.

“…To evaluate the influence of main channel–floodplain connectivity on fish assemblage diversity in floodplains associated with streams and small rivers, fish…”
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Heterotopic ossification after central nervous system trauma: A current review by Sullivan, M P, Torres, S J, Mehta, S, Ahn, J

“…Neurogenic heterotopic ossification (NHO) is a disorder of aberrant bone formation affecting one in five patients sustaining a spinal cord injury or traumatic…”
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