Search Results - "SULLIVAN, Mark A"
-
1
U3 Region in the HIV‑1 Genome Adopts a G‑Quadruplex Structure in Its RNA and DNA Sequence
Published in Biochemistry (Easton) (29-04-2014)“…Genomic regions rich in G residues are prone to adopt G-quadruplex structure. Multiple Sp1-binding motifs arranged in tandem have been suggested to form this…”
Get full text
Journal Article -
2
A Crucial Role for p90RSK-Mediated Reduction of ERK5 Transcriptional Activity in Endothelial Dysfunction and Atherosclerosis
Published in Circulation (New York, N.Y.) (29-01-2013)“…Diabetes mellitus is a major risk factor for cardiovascular mortality by increasing endothelial cell (EC) dysfunction and subsequently accelerating…”
Get full text
Journal Article -
3
Display of the HIV envelope protein at the yeast cell surface for immunogen development
Published in PloS one (18-10-2018)“…As a step toward the development of variant forms of Env with enhanced immunogenic properties, we have expressed the glycoprotein in the yeast surface display…”
Get full text
Journal Article -
4
CNS Delivery of Vectored Prion-specific Single-chain Antibodies Delays Disease Onset
Published in Molecular therapy (01-03-2008)“…A unifying characteristic of prion diseases is the conversion of a normal cellular protein (PrPc) to an abnormal pathogenic conformation, designated PrPsc…”
Get full text
Journal Article -
5
Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function
Published in The Journal of clinical investigation (01-03-2015)“…Disturbed blood flow (d-flow) causes endothelial cell (EC) dysfunction, leading to atherosclerotic plaque formation. We have previously shown that d-flow…”
Get full text
Journal Article -
6
Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice
Published in Molecular therapy (01-08-2010)“…Alzheimer's disease (AD) is a progressive dementing disorder characterized by age-related amyloid-beta (Aβ) deposition, neurofibrillary tangles, and synapse…”
Get full text
Journal Article -
7
Development and characterization of antibody reagents for detecting nanoparticles
Published in Nanoscale (21-12-2015)“…The increasing use of nanoparticles (NPs) in technological applications and in commercial products has escalated environmental health and safety concerns. The…”
Get more information
Journal Article -
8
Phosphorylation of Protein Inhibitor of Activated STAT1 (PIAS1) by MAPK-Activated Protein Kinase-2 Inhibits Endothelial Inflammation via Increasing Both PIAS1 Transrepression and SUMO E3 Ligase Activity
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2013)“…OBJECTIVE—Protein inhibitor of activated signal transducer and activator of transcription-1 (PIAS1) is known to function as small ubiquitin-like modifier…”
Get full text
Journal Article -
9
Differentiation of Candida albicans and Candida dubliniensis by Using Recombinant Human Antibody Single-Chain Variable Fragments Specific for Hyphae
Published in Journal of Clinical Microbiology (01-03-2003)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
10
Anti-idiotypic monobodies for immune response profiling
Published in Methods (San Diego, Calif.) (01-09-2012)“…A major goal in the study of autoimmune disease is the identification of biomarkers of disease to allow early diagnosis and initiation of treatment. The…”
Get full text
Journal Article -
11
Drop-out phagemid vector for switching from phage displayed affinity reagents to expression formats
Published in Analytical biochemistry (15-05-2011)“…Affinity reagents that are generated by phage display are typically subcloned into an expression vector for further biochemical characterization. This insert…”
Get full text
Journal Article -
12
Anti-Idiotypic Monobodies Derived from a Fibronectin Scaffold
Published in Biochemistry (Easton) (12-03-2013)“…Mimetics of conformational protein epitopes have broad applications but have been difficult to identify using conventional peptide phage display. The 10th type…”
Get full text
Journal Article -
13
Creep Rupture and Fatigue Behavior of a Notched Oxide/Oxide Ceramic Matrix Composite at an Elevated Temperature
Published in International journal of applied ceramic technology (01-03-2011)“…Oxide/oxide ceramic matrix composites (CMCs) have the potential to provide a longer lifetime and better strength when subjected to thermomechanical loads due…”
Get full text
Journal Article -
14
Identification of human α-synuclein specific single chain antibodies
Published in Biochemical and biophysical research communications (03-11-2006)“…Parkinson’s disease (PD) is a common neurodegenerative disease of unknown etiology. Evidence suggests a role for protein misfolding in disease pathogenesis…”
Get full text
Journal Article -
15
The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation
Published in Molecular biology of the cell (01-09-2005)“…RNA interference (RNAi) was used to characterize the requirement of protein glycosylation for cell membrane stability during cytokinesis in the early embryo…”
Get full text
Journal Article -
16
Rapid isolation of single-chain antibodies for structural genomics
Published in Journal of structural and functional genomics (01-09-2005)“…High throughput approaches to structural genomics requires expression, purification, and crystallization of proteins derived from predicted open reading frames…”
Get full text
Journal Article -
17
Recombinant human antibody single chain variable fragments reactive with Candida albicans surface antigens
Published in Journal of immunological methods (01-11-2001)“…A combinatorial phage display library expressing human immunoglobulin heavy and light chain variable regions was used to identify phage clones capable of…”
Get full text
Journal Article -
18
Inhibition of Candida albicans adhesion by recombinant human antibody single-chain variable fragment specific for Als3p
Published in FEMS immunology and medical microbiology (01-11-2008)“…The Candida albicans adhesin, Als3p, was identified as a potential cognate antigen for previously described human antibody fragments [single-chain variable…”
Get full text
Journal Article -
19
Why the Georgist Movement Has Not Succeeded: A Personal Response to the Question Raised by Warren J. Samuels
Published in The American journal of economics and sociology (01-07-2003)“…The intellectual/reform movement founded by Henry George has not succeeded, but it has survived. George both accepted and challenged prevailing 19th-century…”
Get full text
Journal Article -
20
Evaluation of a forage allocation model for Theodore Roosevelt National Park
Published in Journal of environmental management (01-02-2002)“…We developed a forage allocation model using a deterministic, linear optimization module in a commercially available spreadsheet package to help resource…”
Get full text
Journal Article