Search Results - "SULLIVAN, Maren"

Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade by Flaig, Thomas W, Salzmann-Sullivan, Maren, Su, Lih-Jen, Zhang, Zhiyong, Joshi, Molishree, Gijón, Miguel A, Kim, Jihye, Arcaroli, John J, Van Bokhoven, Adrie, Lucia, M Scott, La Rosa, Francisco G, Schlaepfer, Isabel R

“…Prostate cancer (PCa) is the most common malignancy among Western men and the second leading-cause of cancer related deaths. For men who develop metastatic…”
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Epidemiological Approach to Identifying Genetic Predispositions for Atypical Hemolytic Uremic Syndrome by Sullivan, Maren, Erlic, Zoran, Hoffmann, Michael M., Arbeiter, Klaus, Patzer, Ludwig, Budde, Klemens, Hoppe, Bernd, Zeier, Martin, Lhotta, Karl, Rybicki, Lisa A., Bock, Andreas, Berisha, Gani, Neumann, Hartmut PH

“…Summary Atypical hemolytic uremic syndrome (aHUS) is caused by several susceptibility genes. A registry including analyses of susceptibility genes, familial…”
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CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions by Joshi, Molishree, Stoykova, Gergana E, Salzmann-Sullivan, Maren, Dzieciatkowska, Monika, Liebman, Lauren N, Deep, Gagan, Schlaepfer, Isabel R

“…Prostate cancer (PCa) is the most common cancer in men, and the global burden of the disease is rising. The majority of PCa deaths are due to metastasis that…”
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Preclinical evaluation of teleglenastat (CB-839) in prostate cancer by Lam, Elaine T., Su, Lih-Jen, Salzmann-Sullivan, Maren, Nordeen, Steven K., Flaig, Thomas W.

“…378 Background: Glutaminase (GLS) levels are upregulated in prostate cancer [PMID: 28138303, 16897757]. The androgen receptor signaling pathway enhances the…”
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OR34-4 ATF3 Is A Converging Point For AR Signaling And Fatty Acid Oxidation In Prostate Cancer by Joshi, Molishree, Salzmann-Sullivan, Maren, Schlaepfer, Isabel

“…Prostate cancer (PCa) is the second most prevalent cancer and leading causes of death among men worldwide. Androgen deprivation is the first line of treatment…”
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Abstract A021: CPT1A-mediated fat oxidation and its role in the immune response to prostate cancer by Guth, Amanda M., Salzmann-Sullivan, Maren, Beaton, Camille, Goldkorn, Amir, Gibson, Emily A., Kessler, Elizabeth, Lam, Elaine, Flaig, Thomas, Agarwal, Rajesh, Schlaepfer, Isabel R.

“…Abstract Background and Rationale: While impressive improvements in immunology have led to the identification of immune checkpoint proteins such as CTLA-4 and…”
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Germline Mutations of the TMEM127 Gene in Patients with Paraganglioma of Head and Neck and Extraadrenal Abdominal Sites by Neumann, Hartmut P. H, Sullivan, Maren, Winter, Aurelia, Malinoc, Angelica, Hoffmann, Michael M, Boedeker, Carsten C, Bertz, Hartmut, Walz, Martin K, Moeller, Lars C, Schmid, Kurt W, Eng, Charis

“…Background: Hereditary pheochromocytoma is associated with germline mutations of a set of susceptibility genes to which the TMEM127 gene has recently been…”
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Abstract 1483: Lipid oxidation via CPT1 as a target for prostate cancer imaging and therapy by Schlaepfer, Isabel R., Salzmann-Sullivan, Maren, Su, Lih-Jen, Glode, L.Michael, Flaig, Thomas

“…Abstract Introduction: Prostate cancer (PCa) is the most common cancer in males and is currently treated medically with androgen deprivation therapy. However,…”
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Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer by Schlaepfer, Isabel R., Deep, Gagan, Agarwal, Rajesh, Zhang, Zhiyong, Salzmann-Sullivan, Maren, Su, Lih-Jen, Flaig, Thomas

“…Abstract Background: Androgen deprivation results in hypoxia in prostate cancer (PCa) cells and subsequently enhances the transcriptional activity of AR…”
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Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3 by Malinoc, Angelica, Sullivan, Maren, Wiech, Thorsten, Schmid, Kurt Werner, Jilg, Cordula, Straeter, Joern, Deger, Serdar, Hoffmann, Michael M, Bosse, Alexander, Rasp, Gerd, Eng, Charis, Neumann, Hartmut P H

“…The etiology and pathogenesis of renal cell carcinoma (RCC) are only partially understood. Key findings in hereditary RCC, which may be site specific or a…”
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Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out by NEUMANN, Hartmut P. H, ERLIC, Zoran, LAMPE, Karen, FISCHER, Markus, EDELMAN, Emily, BENN, Diana E, ROBINSON, Bruce G, WIEGAND, Stefanie, RASP, Gerd, STUCK, Boris A, HOFFMANN, Michael M, SULLIVAN, Maren, BOEDEKER, Carsten C, SEVILLA, Maria A, WEISS, Marjan M, PECZKOWSKA, Mariola, KUBASZEK, Agata, PIGNY, Pascal, WARD, Robyn L, LEAROYD, Diana, CROXSON, Michael, ZABOLOTNY, Dmitry, YAREMCHUK, Svetlana, RYBICKI, Lisa A, DRAF, Wolfgang, MURESAN, Mihaela, LORENZ, Robert R, KNIPPING, Stephan, STROHM, Michael, DYCKHOFF, Gerhard, MATTHIAS, Christoph, REISCH, Nicole, PREUSS, Simon F, ESSER, Dirk, ROBLEDO, Mercedes, WALTER, Martin A, KAFTAN, Holger, STÖVER, Timo, FOTTNER, Christian, GORGUNA, Harald, MALEKPOUR, Mahdi, ZARANDY, Masoud Motasaddi, SCHIPPER, Jörg, BRASE, Christoph, GLIEN, Alexander, HERMSEN, Mario, KÜHNEMUND, Matthias, KOSCIELNY, Sven, SCHWERDTFEGER, Peter, VÄLIMÄKI, Matti, SZYFTER, Witold, FINCKH, Ulrich, ZERRES, Klaus, CASCON, Alberto, OPOCHER, Giuseppe, RIDDER, Gerd J, SCHIAVI, Francesca, JANUSZEWICZ, Andrzej, SUAREZ, Carlos, ENG, Charis, FALCIONI, Maurizio, KWOK, Pingling, BAUTERS, Catherine

“…Multiple genes and their variants that lend susceptibility to many diseases will play a major role in clinical routine. Genetics-based cost reduction…”
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Pathogenicity of DNA Variants and Double Mutations in Multiple Endocrine Neoplasia Type 2 and Von Hippel-Lindau Syndrome by Erlic, Zoran, Hoffmann, Michael M, Sullivan, Maren, Franke, Gerlind, Peczkowska, Mariola, Harsch, Igor, Schott, Matthias, Gabbert, Helmut E, Valimäki, Matti, Preuss, Simon F, Hasse-Lazar, Kornelia, Waligorski, Dariusz, Robledo, Mercedes, Januszewicz, Andrzej, Eng, Charis, Neumann, Hartmut P. H

“…Context: Cancer genetics is fundamental for preventive medicine, in particular in pheochromocytoma-associated syndromes. Variants in two susceptibility genes,…”
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Age‐Related Penetrance of Hereditary Atypical Hemolytic Uremic Syndrome by Sullivan, Maren, Rybicki, Lisa A., Winter, Aurelia, Hoffmann, Michael M, Reiermann, Stefanie, Linke, Hannah, Arbeiter, Klaus, Patzer, Ludwig, Budde, Klemens, Hoppe, Bernd, Zeier, Martin, Lhotta, Karl, Bock, Andreas, Wiech, Thorsten, Gaspert, Ariana, Fehr, Thomas, Woznowski, Magdalena, Berisha, Gani, Malinoc, Angelica, Goek, Oemer‐Necmi, Eng, Charis, Neumann, Hartmut PH

“…Summary Hereditary atypical hemolytic uremic syndrome (aHUS), a dramatic disease frequently leading to dialysis, is associated with germline mutations of the…”
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Systematic comparison of sporadic and syndromic pancreatic islet cell tumors by Erlic, Zoran, Ploeckinger, Ursula, Cascon, Alberto, Hoffmann, Michael M, von Duecker, Laura, Winter, Aurelia, Kammel, Gerit, Bacher, Janina, Sullivan, Maren, Isermann, Berend, Fischer, Lars, Raffel, Andreas, Knoefel, Wolfram Trudo, Schott, Matthias, Baumann, Tobias, Schaefer, Oliver, Keck, Tobias, Baum, Richard P, Milos, Ioana, Muresan, Mihaela, Peczkowska, Mariola, Januszewicz, Andrzej, Cupisti, Kenko, Tönjes, Anke, Fasshauer, Mathias, Langrehr, Jan, von Wussow, Peter, Agaimy, Abbas, Schlimok, Günter, Lamberts, Regina, Wiech, Thorsten, Schmid, Kurt Werner, Weber, Alexander, Nunez, Mercedes, Robledo, Mercedes, Eng, Charis, Neumann, Hartmut P H

“…Pancreatic islet cell tumors (ICTs) occur as sporadic neoplasias or as a manifestation of multiple endocrine neoplasia type 1 (MEN1) and von Hippel–Lindau…”
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Impact of Screening Kindreds for SDHD p.Cys11X as a Common Mutation Associated with Paraganglioma Syndrome Type 1 by Pęczkowska, Mariola, Erlic, Zoran, Hoffmann, Michael M., Furmanek, Mariusz, Ćwikła, Jarosław, Kubaszek, Agata, Prejbisz, Aleksander, Szutkowski, Zbigniew, Kawecki, Andrzej, Chojnowski, Krzysztof, Lewczuk, Anna, Litwin, Mieczysław, Szyfter, Witold, Walter, Martin A., Sullivan, Maren, Eng, Charis, Januszewicz, Andrzej, Neumann, Hartmut P. H.

“…Context and Objective: Germline mutations of the genes SDHB, SDHC, and SDHD predispose to paraganglioma syndromes. Mutation-specific counseling, risk…”
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Age-related neoplastic risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germ line RET Cys634Trp (TGC>TGG) mutation by Milos, Ioana N, Frank-Raue, Karin, Wohllk, Nelson, Maia, Ana Luiza, Pusiol, Eduardo, Patocs, Attila, Robledo, Mercedes, Biarnes, Josefina, Barontini, Marta, Links, Thera P, de Groot, Jan Willem, Dvorakova, Sarka, Peczkowska, Mariola, Rybicki, Lisa A, Sullivan, Maren, Raue, Friedhelm, Zosin, Ioana, Eng, Charis, Neumann, Hartmut P H

“…RET testing in multiple endocrine neoplasia type 2 for molecular diagnosis is the paradigm for the practice of clinical cancer genetics. However, precise data…”
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Age-Related Penetrance of Hereditary Atypical Hemolytic Uremic Syndrome: Penetrance of hereditary aHUS by Sullivan, Maren, Rybicki, Lisa A., Winter, Aurelia, Hoffmann, Michael M, Reiermann, Stefanie, Linke, Hannah, Arbeiter, Klaus, Patzer, Ludwig, Budde, Klemens, Hoppe, Bernd, Zeier, Martin, Lhotta, Karl, Bock, Andreas, Wiech, Thorsten, Gaspert, Ariana, Fehr, Thomas, Woznowski, Magdalena, Berisha, Gani, Malinoc, Angelica, Goek, Oemer-Necmi, Eng, Charis, Neumann, Hartmut PH

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