Search Results - "SUKHU, L"

A Novel Cationic Lipid Greatly Enhances Plasmid DNA Delivery and Expression in Mouse Lung by Wheeler, Carl J., Felgner, Philip L., Tsai, Yali J., Marshall, John, Sukhu, Loretta, Doh, Soeun G., Hartikka, Jukka, Nietupski, Jennifer, Manthorpe, Marston, Nichols, Margaret, Plewe, Michael, Liang, Xiaowu, Norman, Jon, Smith, Alan, Cheng, Seng H.

“…Effective gene therapy for lung tissue requires the use of efficient vehicles to deliver the gene of interest into lung cells. When plasmid DNA encoding…”
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Sodium phosphate enhances plasmid DNA expression in vivo by HARTIKKA, J, BOZOUKOVA, V, MEEK, J, SHEN, N, MANTHORPE, M, JONES, D, MAHAJAN, R, WLOCH, M. K, SAWDEY, M, BUCHNER, C, SUKHU, L, BARNHART, K. M, ABAI, A. M

“…Intramuscular injection of plasmid DNA results in myofiber cell expression of proteins encoded by the DNA. The preferred vehicle for plasmid DNA injections has…”
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Masculinity and Men’s Violence against Known Women in Trinidad—Whose Responsibility? by Sukhu, Raquel L. M.

“…This paper explores the male batterer's account of his violence based on a qualitative study of a sample of working class men, alleged batterers, conducted in…”
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Novel, high expressing and antibiotic-controlled plasmid vectors designed for use in gene therapy by Liang, X, Hartikka, J, Sukhu, L, Manthorpe, M, Hobart, P

“…The promise of effective gene therapy can only be accomplished by high-level expression and regulatable delivery of gene products. To achieve this end, a…”
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Quantitative methods for scoring cell migration and invasion in filter-based assays by Muir, D, Sukhu, L, Johnson, J, Lahorra, M A, Maria, B L

“…The ability of cells to traverse pores in a biocompatible filter provides means for examining cell chemoattraction. Filter-based assays also permit rapid,…”
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Electroporation-Facilitated Delivery of Plasmid DNA in Skeletal Muscle: Plasmid Dependence of Muscle Damage and Effect of Poloxamer 188 by Hartikka, Jukka, Sukhu, Loretta, Buchner, Carol, Hazard, Diane, Bozoukova, Vesselina, Margalith, Michal, Nishioka, Walter K., Wheeler, Carl J., Manthorp, Marston, Sawdey, Michael

“…Electroporation has been reported to facilitate naked DNA gene transfer in skeletal muscle, but has also been implicated in the pathogenesis of electrical…”
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Improved cationic lipid formulations for in vivo gene therapy by Felgner, P L, Tsai, Y J, Sukhu, L, Wheeler, C J, Manthorpe, M, Marshall, J, Cheng, S H

“…The problem of assessing in vivo activity of gene delivery systems is complex. The reporter gene must be carefully chosen depending on the application…”
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Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens by Hartikka, Jukka, Bozoukova, Vesselina, Ferrari, Marilyn, Sukhu, Loretta, Enas, Joel, Sawdey, Michael, Wloch, Mary K, Tonsky, Katja, Norman, Jon, Manthorpe, Marston, Wheeler, Carl J

“…This report characterizes Vaxfectin, a novel cationic and neutral lipid formulation which enhances antibody responses when complexed with an antigen-encoding…”
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Vaxfectin enhances antigen specific antibody titers and maintains Th1 type immune responses to plasmid DNA immunization by Reyes, Luane, Hartikka, Jukka, Bozoukova, Vesselina, Sukhu, Loretta, Nishioka, Walter, Singh, Gita, Ferrari, Marilyn, Enas, Joel, Wheeler, Carl J, Manthorpe, Marston, Wloch, Mary K

“…Antigen specific immune responses were characterized after intramuscular immunization of BALB/c mice with 5 antigen encoding plasmid DNAs (pDNAs) complexed…”
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Converting an alcohol to an amine in a cationic lipid dramatically alters the co-lipid requirement, cellular transfection activity and the ultrastructure of DNA-cytofectin complexes by Wheeler, Carl J., Sukhu, Loretta, Yang, Gouliang, Tsai, Yali, Bustamente, Carlos, Felgner, Phil, Norman, Jon, Manthorpe, Marston

“…Cytofectins are positively charged lipophilic molecules that readily form complexes with DNA and other anionic polynucleotides. Normally, cytofectins are…”
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Crown of microfilaments in the extending cytoplasmic processes of medulloblastoma glial progenitors by Maria, B L, Cumming, R, Sukhu, L

“…Microfilaments and microtubules play a part in the extension of neuronal processes but their roles in the formation of glial processes have not yet been…”
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