Search Results - "SUISSA, Samy"

Guidelines for the Pharmacologic Treatment of COPD 2023: Canada versus GOLD by Suissa, Samy

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Immortal time bias in observational studies of drug effects by Suissa, Samy

“…Purpose Recent observational studies suggest that various drugs are remarkably effective at reducing morbidity and mortality. These cohort studies used a…”
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Run-in bias in randomised trials: the case of COPD medications by Suissa, Samy

“…Most randomised trials of newer and established medications in chronic obstructive pulmonary disease (COPD) enrol patients who have already been treated, often…”
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Sulfonylureas and the Risks of Cardiovascular Events and Death: A Methodological Meta-Regression Analysis of the Observational Studies by Azoulay, Laurent, Suissa, Samy

“…Recent randomized trials have compared the newer antidiabetic agents to treatments involving sulfonylureas, drugs associated with increased cardiovascular…”
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The effect of anti-acid therapy on survival in idiopathic pulmonary fibrosis: a methodological review of observational studies by Tran, Tanja, Suissa, Samy

“…International treatment guidelines for idiopathic pulmonary fibrosis (IPF) give a conditional recommendation for anti-acid therapy. As some observational…”
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Time‐related biases in pharmacoepidemiology by Suissa, Samy, Dell'Aniello, Sophie

“…Purpose Observational studies using computerized healthcare databases have become popular to investigate the potential effectiveness of old drugs for new…”
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Triple therapy in COPD: understanding the data by Suissa, Samy

“…https://bit.ly/3tOgNdW…”
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Triple therapy trials in COPD: a precision medicine opportunity by Suissa, Samy, Ariel, Amnon

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Making Sense of Triple Inhaled Therapy for COPD by Suissa, Samy, Drazen, Jeffrey M

“…Guidelines for the treatment of chronic obstructive pulmonary disease (COPD) have consistently recommended long-acting inhaled bronchodilators — either…”
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Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…The long-term natural history of chronic obstructive pulmonary disease (COPD) in terms of successive severe exacerbations and mortality is unknown. The authors…”
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Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…The cardiovascular risk of concurrently using long-acting β -agonists (LABAs) and anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative…”
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Comparative Effectiveness and Safety of LABA-LAMA vs LABA-ICS Treatment of COPD in Real-World Clinical Practice by Suissa, Samy, Dell’Aniello, Sophie, Ernst, Pierre

“…Long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are recommended as initial maintenance treatments for COPD, with their…”
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Inhaled corticosteroids in COPD: the clinical evidence by Ernst, Pierre, Saad, Nathalie, Suissa, Samy

“…In this article, we focus on the scientific evidence from randomised trials supporting treatment with inhaled corticosteroids (ICS) in chronic obstructive…”
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Proton-pump inhibitors and increased gastric cancer risk: time-related biases by Suissa, Samy, Suissa, Alain

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Incidence of and Mortality from Venous Thromboembolism in a Real-world Population: The Q-VTE Study Cohort by Tagalakis, Vicky, MD, MSc, Patenaude, Valérie, MSc, Kahn, Susan R., MD, MSc, Suissa, Samy, PhD

“…Abstract Background The public health burden of venous thromboembolism, which includes deep vein thrombosis and pulmonary embolism, is not fully known, and…”
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Cardiovascular disease and COPD: dangerous liaisons? by Rabe, Klaus F, Hurst, John R, Suissa, Samy

“…Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) frequently occur together and their coexistence is associated with worse outcomes…”
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Discussion of Schuemie et al: “A plea to stop using the case‐control design in retrospective database studies” by Schneeweiss, Sebastian, Suissa, Samy

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Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…Long-acting β2 agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are the recommended initial maintenance treatment for chronic obstructive…”
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Statins and Mortality in COPD: A Methodological Review of Observational Studies by Sule, Naheemot Olaoluwa, Suissa, Samy

“…Randomized controlled trials and observational studies have reported conflicting results on the potential beneficial effects of statins on mortality in…”
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Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study by Douros, Antonios, Dell’Aniello, Sophie, Yu, Oriana Hoi Yun, Filion, Kristian B, Azoulay, Laurent, Suissa, Samy

“…AbstractObjectiveTo assess whether adding or switching to sulfonylureas is associated with an increased risk of myocardial infarction, ischaemic stroke,…”
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