Search Results - "SUGIYAMA, Michiko"

Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial by Hosono, Kunihiro, Endo, Hiroki, Takahashi, Hirokazu, Sugiyama, Michiko, Sakai, Eiji, Uchiyama, Takashi, Suzuki, Kaori, Iida, Hiroshi, Sakamoto, Yasunari, Yoneda, Kyoko, Koide, Tomoko, Tokoro, Chikako, Abe, Yasunobu, Inamori, Masahiko, Nakagama, Hitoshi, Nakajima, Atsushi

“…The biguanide metformin is widely used for treating diabetes mellitus. We previously showed the chemopreventive effect of metformin in two rodent models of…”
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Nutritional Status and Nutritional Management Implementation for Residents with Disabilities in Welfare Facilities: A Nationwide Survey in Japan by OHWADA, Hiroko, NAKAYAMA, Takeo, SUGIYAMA, Michiko, FUJITANI, Asami, SHIMANUKI, Natsumi, KAWABATA, Asuka, TOMITA, Fumiyo, KATO, Sumiko

“…In Japan, fees for nutritional management (NM) was introduced in April 2009 to improve nutritional care for persons with disabilities residing in welfare…”
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Blood Pressure Elevation of Tubular Specific (P)RR Transgenic Mice and Lethal Tubular Degeneration due to Possible Intracellular Interactions between (P)RR and Alternative Renin Products by Saigo, Sae, Kino, Tabito, Uchida, Kotaro, Sugawara, Takuya, Chen, Lin, Sugiyama, Michiko, Azushima, Kengo, Wakui, Hiromichi, Tamura, Kouichi, Ishigami, Tomoaki

“…The prorenin/renin receptor ((P)RR) is a multifunctional protein that is widely distributed in various organs. Despite intensive research for more than 20…”
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Regulators of Epithelial Sodium Channels in Aldosterone-Sensitive Distal Nephrons (ASDN): Critical Roles of Nedd4L/Nedd4-2 and Salt-Sensitive Hypertension by Ishigami, Tomoaki, Kino, Tabito, Minegishi, Shintaro, Araki, Naomi, Umemura, Masanari, Ushio, Hisako, Saigoh, Sae, Sugiyama, Michiko

“…Ubiquitination is a representative, reversible biological process of the post-translational modification of various proteins with multiple catalytic reaction…”
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Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase by Hosono, Kunihiro, Endo, Hiroki, Takahashi, Hirokazu, Sugiyama, Michiko, Uchiyama, Takashi, Suzuki, Kaori, Nozaki, Yuichi, Yoneda, Kyoko, Fujita, Koji, Yoneda, Masato, Inamori, Masahiko, Tomatsu, Akiko, Chihara, Takeshi, Shimpo, Kan, Nakagama, Hitoshi, Nakajima, Atsushi

“…Metformin is widely used for the treatment of diabetes mellitus. Adenosine monophosphate‐activated protein kinase (AMPK) is known to be activated by metformin…”
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Perioperative nutrition management as an important component of surgical capacity in low‐ and middle‐income countries by Nakahara, Shinji, Nguyen, Do Huy, Bui, An Tho, Sugiyama, Michiko, Ichikawa, Masao, Sakamoto, Tetsuya, Nakamura, Teiji

“…Summary Needs for surgical care are growing in low‐ and middle‐income countries. Existing surgical care capacity indicators, focusing on the availability of…”
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Leptin receptor is involved in STAT3 activation in human colorectal adenoma by Uchiyama, Takashi, Takahashi, Hirokazu, Sugiyama, Michiko, Sakai, Eiji, Endo, Hiroki, Hosono, Kunihiro, Yoneda, Kyoko, Yoneda, Masato, Inamori, Masahiko, Nagashima, Yoji, Inayama, Yoshiaki, Wada, Koichiro, Nakajima, Atsushi

“…The possible role of leptin in colorectal tumors has been investigated in previous studies; however, to date, the conclusions remain under debate. Therefore,…”
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Eplerenone-Resistant Salt-Sensitive Hypertension in Nedd4-2 C2 KO Mice by Kino, Tabito, Ishigami, Tomoaki, Murata, Tsumugi, Doi, Hiroshi, Nakashima-Sasaki, Rie, Chen, Lin, Sugiyama, Michiko, Azushima, Kengo, Wakui, Hiromichi, Minegishi, Shintaro, Tamura, Kouichi

“…The epithelial sodium channel (ENaC) plays critical roles in maintaining fluid and electrolyte homeostasis and is located in the aldosterone-sensitive distal…”
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National survey of the prevalence of swallowing difficulty and tube feeding use as well as implementation of swallowing evaluation in long-term care settings in Japan by Sugiyama, Michiko, Takada, Kento, Shinde, Manami, Matsumoto, Nana, Tanaka, Kazumi, Kiriya, Yumiko, Nishimoto, Etsuko, Kuzuya, Masafumi

“…Aim The present study was carried out to clarify tube feeding utilization and the prevalence of swallowing difficulty among residents in geriatric long‐term…”
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Axillary ultrasound examination is useful for selecting patients optimally suited for sentinel lymph node biopsy after primary systemic chemotherapy by Shigekawa, Takashi, M.D, Sugitani, Ikuko, M.D, Takeuchi, Hideki, M.D., Ph.D, Misumi, Misono, M.D, Nakamiya, Noriko, M.D, Sugiyama, Michiko, M.D, Sano, Hiroshi, M.D, Matsuura, Kazuo, M.D., Ph.D, Takahashi, Takao, M.D., Ph.D, Fujiuchi, Nobuko, M.D., Ph.D, Osaki, Akihiko, M.D., Ph.D, Saeki, Toshiaki, M.D., Ph.D

“…Abstract Background Controversy surrounds the reliability of sentinel lymph node biopsy after primary systemic chemotherapy. In this study, we assessed…”
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Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice by Arakawa, Kentaro, Ishigami, Tomoaki, Nakai-Sugiyama, Michiko, Chen, Lin, Doi, Hiroshi, Kino, Tabito, Minegishi, Shintaro, Saigoh-Teranaka, Sae, Sasaki-Nakashima, Rie, Hibi, Kiyoshi, Kimura, Kazuo, Tamura, Kouichi

“…The interaction between atherosclerosis and commensal microbes through leaky gut syndrome (LGS), which is characterized by impaired intestinal permeability and…”
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Fibrotic focus: An important parameter for accurate prediction of a high level of tumor‐associated macrophage infiltration in invasive ductal carcinoma of the breast by Shimada, Hiroko, Hasebe, Takahiro, Sugiyama, Michiko, Shibasaki, Satomi, Sugitani, Ikuko, Ueda, Shigeto, Gotoh, Yoshiya, Yasuda, Masanori, Arai, Eiichi, Osaki, Akihiko, Saeki, Toshiaki

“…Our group and others have previously reported that a fibrotic focus is a very useful histological factor for the accurate prediction of the outcome of patients…”
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Signature-tagged mutagenesis of Vibrio vulnificus by YAMAMOTO, Mai, KASHIMOTO, Takashige, TONG, Ping, XIAO, Jianbo, SUGIYAMA, Michiko, INOUE, Miyuki, MATSUNAGA, Rie, HOSOHARA, Kohei, NAKATA, Kazue, YOKOTA, Kenji, OGUMA, Keiji, YAMAMOTO, Koichiro

“…Vibrio vulnificus is the causative agent of primary septicemia, wound infection and gastroenteritis in immunocompromised people. In this study,…”
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Neoadjuvant triweekly nanoparticle albumin-bound paclitaxel followed by epirubicin and cyclophosphamide for Stage II/III HER2-negative breast cancer: evaluation of efficacy and safety by Shimada, Hiroko, Ueda, Shigeto, Saeki, Toshiaki, Shigekawa, Takashi, Takeuchi, Hideki, Hirokawa, Eiko, Sugitani, Ikuko, Sugiyama, Michiko, Takahashi, Takao, Matsuura, Kazuo, Yamane, Tomohiko, Kuji, Ichiei, Hasebe, Takahiro, Osaki, Akihiko

“…Nanoparticle albumin-bound paclitaxel (nab-PTX) is a solvent-free paclitaxel coupled to human albumin without an associated increase in toxicity. The…”
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Inhibition of peroxisome proliferator‐activated receptor γ activity suppresses pancreatic cancer cell motility by Nakajima, Atsushi, Tomimoto, Ayako, Fujita, Koji, Sugiyama, Michiko, Takahashi, Hirokazu, Ikeda, Ikuko, Hosono, Kunihiro, Endo, Hiroki, Yoneda, Kyoko, Iida, Hiroshi, Inamori, Masahiko, Kubota, Kensuke, Saito, Satoru, Nakajima, Noriko, Wada, Koichiro, Nagashima, Yoji, Nakagama, Hitoshi

“…Peroxisome proliferator‐activated receptor γ (PPARγ) is a ligand‐activated transcription factor that has been implicated in the carcinogenesis and progression…”
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Grading system for blood vessel tumor emboli of invasive ductal carcinoma of the breast by Sugiyama, Michiko, MD, Hasebe, Takahiro, MD, PhD, Shimada, Hiroko, MD, Takeuchi, Hideki, MD, PhD, Shimizu, Kyoko, MT, Shimizu, Michio, MD, PhD, Yasuda, Masanori, MD, PhD, Ueda, Shigeto, MD, PhD, Shigekawa, Takashi, MD, PhD, Osaki, Akihiko, MD, PhD, Saeki, Toshiaki, MD, PhD

“…Summary We previously reported that the number of mitotic and apoptotic figures in tumor cells in blood vessel tumor emboli had the greatest significant power…”
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Association of visceral fat accumulation and plasma adiponectin with rectal dysplastic aberrant crypt foci in a clinical population by Takahashi, Hirokazu, Takayama, Tetsuji, Yoneda, Kyoko, Endo, Hiroki, Iida, Hiroshi, Sugiyama, Michiko, Fujita, Koji, Yoneda, Masato, Inamori, Masahiko, Abe, Yasunobu, Saito, Satoru, Wada, Koichiro, Nakagama, Hitoshi, Nakajima, Atsushi

“…The association between obesity and the risk of colorectal cancer (CRC) cannot be easily evaluated because CRC itself is associated with a gradual loss of…”
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Inhibition of Peroxisome Proliferator-Activated Receptor γ Promotes Tumorigenesis Through Activation of the β-Catenin / T Cell Factor (TCF) Pathway in the Mouse Intestine by Fujisawa, Toshio, Sugiyama, Michiko, Tomimoto, Ayako, Wada, Koichiro, Endo, Hiroki, Takahashi, Hirokazu, Yoneda, Kyoko, Yoneda, Masato, Inamori, Masahiko, Saito, Satoru, Terauchi, Yasuo, Kadowaki, Takashi, Tsuchiya, Naoto, Nakagama, Hitoshi, Nakajima, Atsushi

“…Although peroxisome proliferator-activated receptor γ (PPARγ) is strongly expressed in the intestinal epithelium, the role of PPARγ in intestinal tumorigenesis…”
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Relationship between estrogen, vasomotor symptoms, and heart rate variability in climacteric women by Akiyoshi, Mihoko, Kato, Kiyoko, Owa, Yoko, Sugiyama, Michiko, Miyasaka, Naoyuki, Obayashi, Satoshi, Kubota, Toshiro, Aso, Takeshi, Kimura, Tetsuya, Moritani, Toshio, Sato, Kenji

“…The present study investigated resting cardiac autonomic function in Japanese climacteric women using heart rate variability (HRV) power spectral analysis to…”
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Metformin suppresses intestinal polyp growth in ApcMin/+ mice by Tomimoto, Ayako, Endo, Hiroki, Sugiyama, Michiko, Fujisawa, Toshio, Hosono, Kunihiro, Takahashi, Hirokazu, Nakajima, Noriko, Nagashima, Yoji, Wada, Koichiro, Nakagama, Hitoshi, Nakajima, Atsushi

“…Metformin is a biguanide derivative that is widely used in the treatment of diabetes mellitus. One of the pharmacological targets of metformin is adenosine…”
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