Search Results - "SUGINO, TAKASHI"

Insights into E-Cadherin Impairment in CDH1 -Unaltered Invasive Lobular Carcinoma: A Comprehensive Bioinformatic Study by Uchida, Shiro, Sugino, Takashi

“…Invasive lobular carcinoma exhibits unique morphological features frequently associated with alterations in . Although some studies have identified…”
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ERBB2-Mutant Gastrointestinal Tumors Represent Heterogeneous Molecular Biology, Particularly in Microsatellite Instability, Tumor Mutation Burden, and Co-Mutated Genes: An In Silico Study by Uchida, Shiro, Sugino, Takashi

“…During recent years, activating mutations in ERBB2 have been reported in solid tumors of various organs, and clinical trials targeting ERBB2-mutant tumors have…”
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Clinicopathological analysis of T2-FLAIR mismatch sign in lower-grade gliomas by Deguchi, Shoichi, Oishi, Takuma, Mitsuya, Koichi, Kakuda, Yuko, Endo, Masahiro, Sugino, Takashi, Hayashi, Nakamasa

“…T2-FLAIR mismatch sign is known as a highly specific imaging marker of IDH-mutant astrocytomas. This study was intended to clarify what the T2-FLAIR mismatch…”
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Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse by Ashizawa, Tadashi, Iizuka, Akira, Nonomura, Chizu, Kondou, Ryota, Maeda, Chie, Miyata, Haruo, Sugino, Takashi, Mitsuya, Koichi, Hayashi, Nakamasa, Nakasu, Yoko, Maruyama, Kouji, Yamaguchi, Ken, Katano, Ikumi, Ito, Mamoru, Akiyama, Yasuto

“…Humanized mouse models using NOD/Shi-scid-IL2rγ (NOG) and NOD/LtSz-scid IL2rγ (NSG) mouse are associated with several limitations, such as long incubation time…”
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Is the presence of edema and necrosis on T2WI pretreatment breast MRI the key to predict pCR of triple negative breast cancer? by Harada, Taiyo L., Uematsu, Takayoshi, Nakashima, Kazuaki, Sugino, Takashi, Nishimura, Seiichirou, Takahashi, Kaoru, Hayashi, Tomomi, Tadokoro, Yukiko, Watanabe, Junichiro, Nakamoto, Shogo, Ito, Takahiro

“…Purpose Given that a pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is an important prognostic factor, evaluating pretreatment…”
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Pathologies of Precursor Lesions of Biliary Tract Carcinoma by Nakanuma, Yasuni, Kakuda, Yuko, Sugino, Takashi, Sato, Yasunori, Fukumura, Yuki

“…Carcinomas and precursor lesions of the biliary tract belong to a spectrum of pancreatobiliary neoplasms that share common histology and cell lineages. Over…”
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Polypoid invasive carcinoma of the gallbladder‐Another challenging polypoid neoplasm by Nakanuma, Yasuni, Sugino, Takashi, Nomura, Yoshikatsu, Watanabe, Hiroyuki, Terada, Takuro

“…Background Invasive gallbladder carcinoma generally presents as nodular‐sclerosing growth. Recently, “polypoid invasive carcinoma (PICA)” showing grossly…”
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Molecular classification of gastric cancer predicts survival in patients undergoing radical gastrectomy based on project HOPE by Furukawa, Kenichiro, Hatakeyama, Keiichi, Terashima, Masanori, Nagashima, Takeshi, Urakami, Kenichi, Ohshima, Keiichi, Notsu, Akifumi, Sugino, Takashi, Yagi, Taisuke, Fujiya, Keiichi, Kamiya, Satoshi, Hikage, Makoto, Tanizawa, Yutaka, Bando, Etsuro, Kanai, Yae, Akiyama, Yasuto, Yamaguchi, Ken

“…Background Gastric cancer (GC) has been classified based on molecular profiling like The Cancer Genome Atlas (TCGA) and Asian Cancer Research Group (ACRG), and…”
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In Silico Identification of Genes Associated with Breast Cancer Progression and Prognosis and Novel Therapeutic Targets by Uchida, Shiro, Sugino, Takashi

“…Molecular mechanisms underlying breast cancer (BC) progression are complex and remain unclear. In this study, we used bioinformatic tools to identify genes…”
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EMID1, a multifunctional molecule identified in a murine model for the invasion independent metastasis pathway by Kawata, Takuya, Muramatsu, Koji, Shishito, Namiko, Ichikawa-Tomikawa, Naoki, Oishi, Takuma, Kakuda, Yuko, Akiyama, Yasuto, Yamaguchi, Ken, Sakamoto, Michiie, Sugino, Takashi

“…EMI Domain Containing 1 (EMID1) was identified as a potential candidate metastasis-promoting gene. We sought to clarify the molecular function of EMID1 and the…”
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Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors by Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken

“…Mutually exclusive KIT and PDGFRA mutations are considered to be the earliest events in gastrointestinal stromal tumors (GIST), but insufficient for their…”
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Intraductal Papillary Neoplasm of Bile Duct: Updated Clinicopathological Characteristics and Molecular and Genetic Alterations by Nakanuma, Yasuni, Uesaka, Katsuhiko, Kakuda, Yuko, Sugino, Takashi, Kubota, Keiichi, Furukawa, Toru, Fukumura, Yuki, Isayama, Hiroyuki, Terada, Takuro

“…Intraductal papillary neoplasm of the bile duct (IPNB), a pre-invasive neoplasm of the bile duct, is being established pathologically as a precursor lesion of…”
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Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations by Hatakeyama, Keiichi, Muramatsu, Koji, Nagashima, Takeshi, Kawanishi, Yuichi, Fukumura, Ryutaro, Ohshima, Keiichi, Shimoda, Yuji, Kenmotsu, Hirotsugu, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Sugino, Takashi, Yamaguchi, Ken

“…Targeted sequencing offers an opportunity to select specific drugs for cancer patients based on alterations in their genome. However, accurate sequencing…”
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Risk stratification for lymph node metastasis using Epstein–Barr virus status in submucosal invasive (pT1) gastric cancer without lymphovascular invasion: a multicenter observational study by Osumi, Hiroki, Kawachi, Hiroshi, Murai, Katsuyuki, Kusafuka, Kimihide, Inoue, Shuntaro, Kitamura, Masaki, Yoshio, Toshiyuki, Kakusima, Naomi, Ishihara, Ryu, Ono, Hiroyuki, Yamamoto, Noriko, Sugino, Takashi, Nakatsuka, Shinichi, Ida, Satoshi, Nunobe, Souya, Bando, Etsuro, Omori, Takeshi, Takeuchi, Kengo, Fujisaki, Junko

“…Background Lymphovascular invasion (LVI) is a strong predictive factor for lymph node metastasis (LNM) in early gastric cancer (GC). This study investigated…”
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Clinicopathological characteristics of non‐ampullary duodenal tumors and their phenotypic classification by Yoshida, Masao, Shimoda, Tadakazu, Abe, Masato, Kakushima, Naomi, Kawata, Noboru, Takizawa, Kohei, Ono, Hiroyuki, Sugino, Takashi

“…The tumorigenesis of non‐ampullary duodenal epithelial tumors (NADETs) might be different between the oral and anal sides of Vater's papilla. We conducted an…”
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Molecular profile of poorly cohesive gastric carcinoma with special reference to survival by Koseki, Yusuke, Hatakeyama, Keiichi, Terashima, Masanori, Nagashima, Takeshi, Urakami, Kenichi, Ohshima, Keiichi, Aizawa, Daisuke, Sugino, Takashi, Furukawa, Kenichiro, Fujiya, Keiichi, Tanizawa, Yutaka, Bando, Etsuro, Okamura, Yukiyasu, Akiyama, Yasuto, Yamaguchi, Ken

“…Background Patients with poorly cohesive gastric carcinoma (PCC) are known to have poor survival. However, detailed molecular biology of PCC has not been…”
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Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients by Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Matsumura, Kenya, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Kusuhara, Masatoshi, Shiomi, Akio, Ohde, Yasuhisa, Terashima, Masanori, Uesaka, Katsuhiko, Onitsuka, Tetsuro, Nishimura, Seiichiro, Hirashima, Yasuyuki, Hayashi, Nakamasa, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Nakagawa, Masahiro, Ishida, Yuji, Sugino, Takashi, Takahashi, Mitsuru, Akiyama, Yasuto

“…This study aimed to establish the Japanese Cancer Genome Atlas (JCGA) using data from fresh frozen tumor tissues obtained from 5143 Japanese cancer patients,…”
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Discrepancy between endoscopic and pathological ulcerative findings in clinical intramucosal early gastric cancer by Yabuuchi, Yohei, Takizawa, Kohei, Kakushima, Naomi, Kawata, Noboru, Yoshida, Masao, Yamamoto, Yoichi, Kishida, Yoshihiro, Ito, Sayo, Imai, Kenichiro, Ishiwatari, Hirotoshi, Hotta, Kinichi, Matsubayashi, Hiroyuki, Bando, Etsuro, Terashima, Masanori, Sugino, Takashi, Ono, Hiroyuki

“…Background Ulcerative finding (UL) is one of the factors that define the indication and curability of endoscopic resection (ER) in early gastric cancer (EGC)…”
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Does breast cancer growth rate really depend on tumor subtype? Measurement of tumor doubling time using serial ultrasonography between diagnosis and surgery by Nakashima, Kazuaki, Uematsu, Takayoshi, Takahashi, Kaoru, Nishimura, Seiichirou, Tadokoro, Yukiko, Hayashi, Tomomi, Sugino, Takashi

“…Background Breast cancer growth is generally expected to differ between tumor subtypes. We aimed to evaluate tumor doubling time (DT) using ultrasonography and…”
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MAGEA10 expression is a predictive marker of early hepatic recurrence after curative gastrectomy for gastric and gastroesophageal junction cancer by Fujiya, Keiichi, Terashima, Masanori, Ohshima, Keiichi, Aizawa, Daisuke, Sugino, Takashi, Serizawa, Masakuni, Nakamura, Kenichi, Nagashima, Takeshi, Hatakeyama, Keiichi, Urakami, Kenichi, Akiyama, Yasuto, Tsubosa, Yasuhiro, Kitagawa, Yuko, Yamaguchi, Ken

“…Background Resection for hepatic recurrence after gastrectomy in patients with gastric cancer may be curative; however, the prediction of hepatic recurrence…”
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