Search Results - "SUGAWARA, Mitsuru"
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Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells
Published in Respiratory investigation (01-05-2020)“…Coronavirus 229E (HCoV-229E), one of the causes of the common cold, exacerbates chronic obstructive pulmonary disease (COPD) and bronchial asthma. Long-acting…”
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Development of Quantum Dot Lasers for Data-Com and Silicon Photonics Applications
Published in IEEE journal of selected topics in quantum electronics (01-11-2017)“…The device characteristics of semiconductor lasers have been improved with progress in active layer structures. Carrier confinement dimension plays an…”
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A New Algorithm Optimized for Initial Dose Settings of Vancomycin Using Machine Learning
Published in Biological & pharmaceutical bulletin (01-01-2020)“…This study aimed to construct an optimal algorithm for initial dose settings of vancomycin (VCM) using machine learning (ML) with decision tree (DT) analysis…”
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Impact of renal impairment on early development of severe neutropenia with trifluridine/tipiracil treatment for metastatic colorectal cancer
Published in Scientific reports (06-11-2024)“…Trifluridine/tipiracil (FTD/TPI) with or without bevacizumab is an effective treatment for metastatic colorectal cancer (mCRC). As this agent is mainly…”
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Impact of preexisting proteinuria on the development of regorafenib-induced problematic proteinuria in real-world metastatic colorectal cancer treatment
Published in Scientific reports (02-03-2024)“…Regorafenib is the first multikinase inhibitor for treating metastatic colorectal cancer (mCRC). Proteinuria is a frequently encountered adverse effect,…”
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In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid
Published in International journal of pharmaceutics (17-01-2011)“…Dietary polyphenols are thought to be beneficial for human health as antioxidants. Coffee beans contain a common polyphenol, chlorogenic acid. Chlorogenic acid…”
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Usefulness of the Albumin–Bilirubin Score in Determining the Initial Dose of Voriconazole for Patients with Liver Cirrhosis
Published in Biological & pharmaceutical bulletin (01-02-2023)“…The Child–Pugh score is widely used to assess liver function and estimate drug clearance in patients with liver cirrhosis. Recently, the albumin–bilirubin…”
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Impact of reducing day 1 dexamethasone dose in anthracycline-containing regimens on acute gastrointestinal symptoms associated with breast cancer treatment
Published in Scientific reports (02-12-2021)“…The potential of steroid sparing from day 2 onward is reported in anthracycline-containing regimens for breast cancer treatment. We evaluated whether the…”
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Risk Analysis of Denosumab-Induced Hypocalcemia in Bone Metastasis Treatment: Renal Dysfunction Is Not a Risk Factor for Its Incidence in a Strict Denosumab Administration Management System with Calcium/Vitamin D Supplementation
Published in Biological & pharmaceutical bulletin (01-12-2021)“…We have reported that a strict denosumab administration management system with oral calcium/vitamin D supplementation attenuates denosumab-induced hypocalcemia…”
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Evaluation of the impact of systemic dexamethasone dosage on docetaxel-induced hand-foot syndrome in patients with breast cancer
Published in Scientific reports (18-06-2024)“…Hand-foot syndrome (HFS) is a frequently occurring and treatment-requiring adverse effect of docetaxel. We previously reported that systemic dexamethasone…”
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Preexisting autoimmune disease is a risk factor for immune-related adverse events: a meta-analysis
Published in Supportive care in cancer (01-12-2021)“…Purpose Patients with preexisting autoimmune disease (PAD) are often excluded from clinical trials assessing immune checkpoint inhibitors (ICIs). Therefore,…”
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Validation of the usefulness of artificial neural networks for risk prediction of adverse drug reactions used for individual patients in clinical practice
Published in PloS one (29-07-2020)“…Artificial neural networks are the main tools for data mining and were inspired by the human brain and nervous system. Studies have demonstrated their…”
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Impact of systemic dexamethasone dosage on docetaxel-induced oral mucositis in patients with breast cancer
Published in Scientific reports (22-06-2023)“…Oral mucositis (OM) is a common adverse effect of docetaxel-containing treatment. This study aimed to assess whether dexamethasone (DEX) dose-dependently…”
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Anteriorly Tilted Coronal CT of Paranasal Sinuses for Endoscopic Sinus Surgery
Published in The Tohoku Journal of Experimental Medicine (2024)“…Conventional coronal CT scans of paranasal sinuses, aligned perpendicularly to the nasal floor, often deviate significantly from the endoscopic view during…”
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Evaluation of risk factors associated with carboplatin and nab-paclitaxel treatment suspension in patients with non-small cell lung cancer
Published in Supportive care in cancer (01-05-2022)“…Purpose Carboplatin (CBDCA) + nanoparticle albumin-bound paclitaxel (nab-PTX) is one of the most effective chemotherapeutic regimens for advanced non-small…”
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Impact of systemic dexamethasone administration on oral mucositis induced by anthracycline-containing regimens in breast cancer treatment
Published in Scientific reports (22-07-2022)“…Oral mucositis (OM) is one of the most common complications associated with chemotherapy. Here, we evaluated whether systemic dexamethasone (DEX) dosage in…”
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Development of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Simultaneous Determination of Linezolid and Tedizolid in Human Plasma
Published in Biological & pharmaceutical bulletin (01-04-2022)“…It is important to select appropriate antibiotics for infection control. Linezolid and tedizolid are newly developed and synthesized oxazolidinone…”
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Effect of baseline anemia on the efficacy of docetaxel and ramucirumab for advanced non-small cell lung cancer treatment
Published in BMC cancer (21-10-2024)“…Docetaxel (DOC) and ramucirumab (RAM) is one of the most effective regimens for advanced non-small cell lung cancer (NSCLC) treatment. In our previous study,…”
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Construction of a Risk Prediction Model of Extended Release Oxycodone Tablet-Induced Nausea and Clarification of Predictive Factors
Published in Biological & pharmaceutical bulletin (01-04-2021)“…Nausea is a typical adverse event associated with opioids. In this study, we performed logistic regression analysis with the aim of clarifying the risk factors…”
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Risk factor analysis for taxane-associated acute pain syndrome under the dexamethasone prophylaxis
Published in Supportive care in cancer (01-12-2021)“…Purpose Taxane-associated acute pain syndrome (T-APS) reportedly occurs in approximately 70% of patients undergoing therapy. We have previously reported that…”
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