Search Results - "SUBBARAO V. V."
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Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction
Published in Journal of the American College of Cardiology (08-05-2018)“…Trehalose (TRE) is a natural, nonreducing disaccharide synthesized by lower organisms. TRE exhibits an extraordinary ability to protect cells against different…”
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Mitochondrial mutations and mitoepigenetics: Focus on regulation of oxidative stress-induced responses in breast cancers
Published in Seminars in cancer biology (01-08-2022)“…•Epigenetic regulation of mitochondrial DNA (mtDNA) (mitoepigenetics) is an emerging and fast developing field of research.•Cancer cells contain oxidative…”
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3
The Role of Tumor Associated Macrophages (TAMs) in Cancer Progression, Chemoresistance, Angiogenesis and Metastasis - Current Status
Published in Current medicinal chemistry (2021)“…Tumor associated macrophages (TAMs), located in the tumor microenvironment (TME), play a significant role in cancer cell survival and progression. TAMs have…”
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4
Inhibitory Effect of Polyphenols from the Whole Green Jackfruit Flour against α-Glucosidase, α-Amylase, Aldose Reductase and Glycation at Multiple Stages and Their Interaction: Inhibition Kinetics and Molecular Simulations
Published in Molecules (Basel, Switzerland) (14-03-2022)“…For the first time, α-glucosidase, α-amylase, aldose reductase, and glycation at multiple stages inhibitory assays were used to explore the antidiabetic…”
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5
COVID-19: Diabetes Perspective-Pathophysiology and Management
Published in Pathogens (Basel) (25-01-2023)“…Recent evidence relating to the impact of COVID-19 on people with diabetes is limited but continues to emerge. COVID-19 pneumonia is a newly identified illness…”
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6
Variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Vaccine Effectiveness
Published in Vaccines (Basel) (01-10-2022)“…The incidence and death toll due to SARS-CoV-2 infection varied time-to-time; and depended on several factors, including severity (viral load), immune status,…”
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7
Comparative Evaluation of Modified Canal Staining and Clearing Technique, Cone-Beam Computed Tomography, Peripheral Quantitative Computed Tomography, Spiral Computed Tomography, and Plain and Contrast Medium–enhanced Digital Radiography in Studying Root Canal Morphology
Published in Journal of endodontics (01-09-2010)“…Abstract Introduction This study investigated the accuracy of cone-beam computed tomography (CBCT), peripheral quantitative computed tomography (pQCT), spiral…”
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8
The Current Status and Challenges in the Development of Vaccines and Drugs against Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2)
Published in BioMed research international (01-06-2021)“…Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection causes coronavirus disease-19 (COVID-19), which is characterized by clinical…”
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SARS-CoV-2 Infection Positively Correlates with Hyperglycemia and Inflammatory Markers in COVID-19 Patients: A Clinical Research Study
Published in Diseases (01-07-2024)“…Diabetes mellitus (DM) is a common comorbidity in COVID-19 subjects. Hyperglycemia at hospital admission identified as a major risk factor and is responsible…”
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10
Diversity, Pathogenicity, and Management of Verticillium Species
Published in Annual review of phytopathology (01-01-2009)“…The genus Verticillium encompasses phytopathogenic species that cause vascular wilts of plants. In this review, we focus on Verticillium dahliae, placing…”
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11
Breeding Lettuce for Resistance against Sclerotinia minor
Published in HortScience (01-12-2023)“…Lettuce drop caused by Sclerotinia minor is a damaging disease of romaine lettuce ( Lactuca sativa L.) production in California. Introgression of partial…”
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12
Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme
Published in Molecules (Basel, Switzerland) (01-03-2023)“…CDK4/6 and aromatase are prominent targets for breast cancer drug discovery and are involved in abnormal cell proliferation and growth. Although aromatase…”
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13
Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC)
Published in PloS one (30-11-2017)“…Recent studies from our group and many others have shown the ability of histone deacetylase (HDAC) inhibitors for retarding the growth of carcinomas of cervix,…”
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14
Assessment of Clinical Profile and Treatment Outcome in Vaccinated and Unvaccinated SARS-CoV-2 Infected Patients
Published in Vaccines (Basel) (15-07-2022)“…Vaccines against severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) infection, which causes coronavirus disease-19 (COVID-19) in humans, have been…”
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15
Toxicological considerations when creating nanoparticle-based drugs and drug delivery systems
Published in Expert opinion on drug metabolism & toxicology (01-01-2012)“…The biggest challenge faced by the scientific community involved in drug development is to deliver safe and effective dosage of drugs without causing systemic…”
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16
Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail
Published in Biochemical pharmacology (01-09-2010)“…The Mitogen Activated Protein Kinase (MAPK) pathway plays a key role in melanoma development making it an important therapeutic target. In normal cells, the…”
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17
Enlisting wild grass genes to combat nitrification in wheat farming: A nature-based solution
Published in Proceedings of the National Academy of Sciences - PNAS (31-08-2021)“…Active nitrifiers and rapid nitrification are major contributing factors to nitrogen losses in global wheat production. Suppressing nitrifier activity is an…”
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18
The impact of root dentine conditioning on sealing ability and push-out bond strength of an epoxy resin root canal sealer
Published in International endodontic journal (01-06-2011)“…Neelakantan P, Subbarao C, Subbarao CV, De‐Deus G, Zehnder M. The impact of root dentine conditioning on sealing ability and push‐out bond strength of an epoxy…”
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19
Lipid-based nanocarriers for breast cancer treatment - comprehensive review
Published in Drug delivery (03-05-2016)“…Breast cancer is the second leading cancer-related disease as the most common non-cutaneous malignancy among women. Curative options for breast cancer are…”
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20
Vitamin D in Cancer Prevention and Treatment: A Review of Epidemiological, Preclinical, and Cellular Studies
Published in Cancers (20-09-2024)“…Inhibition of human carcinomas has previously been linked to vitamin D due to its effects on cancer cell proliferation, migration, angiogenesis, and apoptosis…”
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