Search Results - "STURTZ, Franck"

Neuroprotective effect of angiotensin II type 2 receptor stimulation in vincristine-induced mechanical allodynia by Bessaguet, Flavien, Danigo, Aurore, Bouchenaki, Hichem, Duchesne, Mathilde, Magy, Laurent, Richard, Laurence, Sturtz, Franck, Desmoulière, Alexis, Demiot, Claire

“…Peripheral neuropathy is the major dose-limiting side effect of many currently used chemotherapies, such as vincristine (VCR). We recently demonstrated that…”
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Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System by Faye, Pierre Antoine, Poumeaud, François, Miressi, Federica, Lia, Anne Sophie, Demiot, Claire, Magy, Laurent, Favreau, Frédéric, Sturtz, Franck G

“…In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long…”
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Curcumin–cyclodextrin/cellulose nanocrystals improve the phenotype of Charcot-Marie-Tooth-1A transgenic rats through the reduction of oxidative stress by Caillaud, Martial, Msheik, Zeina, Ndong-Ntoutoume, Gautier M-A, Vignaud, Laetitia, Richard, Laurence, Favreau, Frédéric, Faye, Pierre-Antoine, Sturtz, Franck, Granet, Robert, Vallat, Jean-Michel, Sol, Vincent, Desmoulière, Alexis, Billet, Fabrice

“…The most prevalent form of Charcot-Marie-Tooth disease (CMT type 1A) is characterized by duplication of the PMP22 gene, peripheral dysmyelination and decreased…”
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Focus on cell therapy to treat corneal endothelial diseases by Faye, Pierre Antoine, Poumeaud, François, Chazelas, Pauline, Duchesne, Mathilde, Rassat, Marion, Miressi, Federica, Lia, Anne Sophie, Sturtz, Franck, Robert, Pierre-Yves, Favreau, Frédéric, Benayoun, Yohan

“…The cornea is a multi-layered structure which allows fine refraction and provides both resistance to external insults and adequate transparency. The corneal…”
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An overview of ongoing clinical trials assessing pharmacological therapeutic strategies to manage chemotherapy‐induced peripheral neuropathy, based on preclinical studies in rodent models by Bouchenaki, Hichem, Danigo, Aurore, Sturtz, Franck, Hajj, Rodolphe, Magy, Laurent, Demiot, Claire

“…Chemotherapy‐induced peripheral neuropathy (CIPN) is a major dose‐limiting side effect induced by a variety of chemotherapeutic agents. Symptoms are mainly…”
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Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation by Bessaguet, Flavien, Danigo, Aurore, Magy, Laurent, Sturtz, Franck, Desmoulière, Alexis, Demiot, Claire

“…Sensory defects associated with small-fiber neuropathy (SFN) can lead to profound disabilities. The relationship between the sensory nervous system and…”
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Deciphering the links between psychological stress, depression, and neurocognitive decline in patients with Down syndrome by Poumeaud, François, Mircher, Clotilde, Smith, Peter J., Faye, Pierre-Antoine, Sturtz, Franck G.

“…The relationships between psychological stress and cognitive functions are still to be defined despite some recent progress. Clinically, we noticed that…”
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CovCopCan: An efficient tool to detect Copy Number Variation from amplicon sequencing data in inherited diseases and cancer by Derouault, Paco, Chauzeix, Jasmine, Rizzo, David, Miressi, Federica, Magdelaine, Corinne, Bourthoumieu, Sylvie, Durand, Karine, Dzugan, Hélène, Feuillard, Jean, Sturtz, Franck, Mérillou, Stéphane, Lia, Anne-Sophie

“…Molecular diagnosis is an essential step of patient care. An increasing number of Copy Number Variations (CNVs) have been identified that are involved in…”
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Netazepide, an Antagonist of Cholecystokinin Type 2 Receptor, Prevents Vincristine-Induced Sensory Neuropathy in Mice by Bernard, Amandine, Mroué, Mohamad, Bourthoumieu, Sylvie, Boyce, Malcolm, Richard, Laurence, Sturtz, Franck, Demiot, Claire, Danigo, Aurore

“…Among the vinca-alkaloid class, vincristine is a potent chemotherapeutic agent with significant neurotoxic effects and is employed to address a wide spectrum…”
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Epithelial changes of congenital intestinal obstruction in a rat model by Ballouhey, Quentin, Fourcade, Laurent, Richard, Laurence, Bellet, Camille, El Hamel, Chaharazed, Vallat, Jean Michel, Sturtz, Franck, Bourthoumieu, Sylvie

“…Intestinal atresia is a rare congenital affliction that is often associated with severe bacterial infections despite adequate neonatal surgery. Previous…”
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The Cholecystokinin Type 2 Receptor, a Pharmacological Target for Pain Management by Bernard, Amandine, Danigo, Aurore, Bourthoumieu, Sylvie, Mroué, Mohamad, Desmoulière, Alexis, Sturtz, Franck, Rovini, Amandine, Demiot, Claire

“…Over the past decades, accumulating evidence has demonstrated a pivotal role of cholecystokinin type 2 receptor (CCK2R) in pain modulation. The established…”
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Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice by Bouchenaki, Hichem, Danigo, Aurore, Bernard, Amandine, Bessaguet, Flavien, Richard, Laurence, Sturtz, Franck, Balayssac, David, Magy, Laurent, Demiot, Claire

“…Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral neuropathy, a dose-limiting effect characterized by cold and tactile…”
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Improving genetic testing pathways for transthyretin amyloidosis in France: challenges and strategies by Hebrard, Bérénice, Babonneau, Marie-Lise, Charron, Philippe, Consolino, Emilie, Dauriat, Benjamin, Dupin-Deguine, Delphine, Fargeaud, Dominique, Farrugia, Agnès, Giguet-Valard, Anna-Gaëlle, Guijarro, Damien, Inamo, Jocelyn, Jeanneteau, Julien, Mazzella, Jean-Michaël, Michon, Claire-Cécile, Millat, Gilles, Mouquet, Frédéric, Oghina, Silvia, Pereon, Yann, Poinsignon, Vianney, Pompougnac, Julie, Proukhnitzky, Julie, Schaefer, Elise, Sturtz, Franck, Trosdorf, Mathilde, Auguste, Anne, Canali, Giorgia, Combes, Alexandre, Funalot, Benoît, Damy, Thibaud

“…Transthyretin amyloidosis (ATTR) is a severe and rare disease characterized by the progressive deposition of misfolded transthyretin proteins, causing…”
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The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome by Mégarbané, André, Ravel, Aimé, Mircher, Clotilde, Sturtz, Franck, Grattau, Yann, Rethoré, Marie-Odile, Delabar, Jean-Maurice, Mobley, William C

“…Trisomy 21 or Down syndrome is a chromosomal disorder resulting from the presence of all or part of an extra Chromosome 21. It is a common birth defect, the…”
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Effect of leucovorin (folinic acid) on the developmental quotient of children with Down's syndrome (trisomy 21) and influence of thyroid status by Blehaut, Henri, Mircher, Clotilde, Ravel, Aimé, Conte, Martine, de Portzamparc, Veronique, Poret, Gwendael, de Kermadec, Françoise Huon, Rethore, Marie-Odile, Sturtz, Franck G

“…Seven genes involved in folate metabolism are located on chromosome 21. Previous studies have shown that folate deficiency may contribute to mental retardation…”
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Neuroprotective Effect of Polyvalent Immunoglobulins on Mouse Models of Chemotherapy-Induced Peripheral Neuropathy by Mroué, Mohamad, Bessaguet, Flavien, Nizou, Angélique, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Danigo, Aurore, Demiot, Claire

“…The occurrence of neuropathic pain in chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting effect of many commonly-used anticancer…”
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Involvement of the enteroendocrine system in intestinal obstruction by Ballouhey, Quentin, Richard, Laurence, Fourcade, Laurent, Ben Rhaiem, Ines, Vallat, Jean Michel, Sturtz, Franck, Bourthoumieu, Sylvie

“…Intestinal atresia, a rare congenital condition, is often associated with intestinal motility disorders despite adequate neonatal surgery. Previous studies…”
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The Angiotensin II Type 2 Receptor, a Target for Protection and Regeneration of the Peripheral Nervous System? by Danigo, Aurore, Rovini, Amandine, Bessaguet, Flavien, Bouchenaki, Hichem, Bernard, Amandine, Sturtz, Franck, Bourthoumieu, Sylvie, Desmoulière, Alexis, Magy, Laurent, Demiot, Claire

“…Preclinical evidence, accumulated over the past decade, indicates that the angiotensin II type 2 receptor (AT2R) stimulation exerts significant neuroprotective…”
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Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model by Mousseau, Yoanne, Mollard, Séverine, Faucher-Durand, Karine, Richard, Laurence, Nizou, Angélique, Cook-Moreau, Jeanne, Baaj, Yasser, Qiu, Hao, Plainard, Xavier, Fourcade, Laurent, Funalot, Benoit, Sturtz, Franck G.

“…Most of the antiangiogenic strategies used in oncology principally target endothelial cells through the vascular endothelial growth factor (VEGF) pathway…”
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Neuroprotective Effect of Ramipril Is Mediated by AT2 in a Mouse MODEL of Paclitaxel-Induced Peripheral Neuropathy by Bouchenaki, Hichem, Bernard, Amandine, Bessaguet, Flavien, Frachet, Simon, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Demiot, Claire, Danigo, Aurore

“…Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) induces numerous symptoms affecting patient quality of life, leading to decreased doses or even to…”
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