Search Results - "STURM, Sonja"
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Liquid chromatography–nuclear magnetic resonance coupling as alternative to liquid chromatography–mass spectrometry hyphenations: Curious option or powerful and complementary routine tool?
Published in Journal of Chromatography A (12-10-2012)“…► NMR spectroscopy is the major de novo structure elucidation method in liquid state. ► LC–NMR combines high resolution separation with unequivocal structure…”
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NMR-Based Chromatography Readouts: Indispensable Tools to "Translate" Analytical Features into Molecular Structures
Published in Cells (Basel, Switzerland) (07-11-2022)“…Gaining structural information is a must to allow the unequivocal structural characterization of analytes from natural sources. In liquid state, NMR…”
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Prebiotic Effects of Partially Hydrolyzed Guar Gum on the Composition and Function of the Human Microbiota-Results from the PAGODA Trial
Published in Nutrients (28-04-2020)“…(1) Background: Alterations in the structural composition of the human gut microbiota have been identified in various disease entities along with exciting…”
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Towards eco‐friendly secondary plant metabolite quantitation: Ultra high performance supercritical fluid chromatography applied to common vervain (Verbena officinalis L.)
Published in Journal of separation science (01-02-2020)“…This report presents the first ultra high performance supercritical fluid chromatography diode array detector based assay for simultaneous determination of…”
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Combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR to Monitor In Vitro Vitetrifolin D Phase I and II Metabolism
Published in Metabolites (09-08-2021)“…By combining HPLC-DAD-QTOF-MS and HPLC-SPE-NMR, the in vitro metabolism of vitetrifolin D, a pharmacologically active key molecule from in liver cell…”
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A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature
Published in Scientific reports (14-08-2017)“…The human cytochrome P450 2D6 (CYP2D6) enzyme is part of phase-I metabolism and metabolizes at least 20% of all clinically relevant drugs. Therefore, it is an…”
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Recent advances on HPLC/MS in medicinal plant analysis—An update covering 2011–2016
Published in Journal of pharmaceutical and biomedical analysis (05-01-2018)“…[Display omitted] •The most recent LC–MS applications related to natural products are summarized.•A short overview on current technical advancements is…”
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Studi sui tratti di qualità negativa nelle nuove viti mediamente resistenti alle malattie fungine
Published in BIO Web of Conferences (2022)“…The varieties of vines tolerant to the main fungal diseases are the object of growing interest because they require fewer treatments for the production of…”
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LC-DAD-MS/SPE-NMR Hyphenation. A Tool for the Analysis of Pharmaceutically Used Plant Extracts: Identification of Isobaric Iridoid Glycoside Regioisomers from Harpagophytum procumbens
Published in Analytical chemistry (Washington) (01-02-2005)“…LC-DAD-MS monitored fractionation of a Harpagophytum procumbens DC. (Pedaliaceae) root extract was combined with a hyphenated LC-DAD-MS/SPE-NMR technique, thus…”
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Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography
Published in Biomedical chromatography (01-02-2009)“…Alkannin and shikonin (A/S) and their derivatives have been found in the roots of several Boraginaceous species and are also produced through plant tissue…”
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Anticancer Activity of Novel Plant Extracts from Trailliaedoxa gracilis (W. W. Smith & Forrest) in Human Carcinoid KRJ-I Cells
Published in Anticancer research (01-01-2010)“…Background: Small intestinal (SI) neuroendocrine tumors (NETs) are rare neoplasms derived from neuroendocrine cells presenting distinct clinical symptoms…”
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Antiproliferative and Pro-apoptotic Effects of Uncaria tomentosa in Human Medullary Thyroid Carcinoma Cells
Published in Anticancer research (01-11-2009)“…Medullary thyroid carcinoma (MTC), a rare calcitonin-producing tumor, is derived from parafollicular C-cells of the thyroid and is characterized by…”
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Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents
Published in Phytochemical analysis (01-09-2006)“…The analytical assessment of edelweiss (Leontopodium alpinum) herb extracts, used in traditional alpine medicine, has resulted in the development of a…”
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Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques--state of the art in natural product HPLC-MS, HPLC-NMR, and CE-MS hyphenations
Published in Natural product reports (01-01-2013)“…Current natural product research is unthinkable without the use of high resolution separation techniques as high performance liquid chromatography or capillary…”
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Anticancer Activity of Novel Extracts from Cautleya gracilis (Smith) Dandy: Apoptosis in Human Medullary Thyroid Carcinoma Cells
Published in Anticancer research (01-09-2008)“…Background: Medullary thyroid carcinoma (MTC) is a calcitonin-producing tumor of the thyroid arising from the parafollicular C-cells. MTC is poorly responsive…”
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Analysis of isoquinoline alkaloids in medicinal plants by capillary electrophoresis-mass spectrometry
Published in Electrophoresis (01-11-1998)“…The technique of capillary electrophoresis - mass spectrometry (CE-MS) was applied for determination of isoquinoline alkaloids in crude methanolic extracts of…”
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Simultaneous Quantitative Analysis of the Major Bioactive Compounds in Gentianae Radix and its Beverages by UHPSFC–DAD
Published in Journal of agricultural and food chemistry (22-06-2022)“…This study presents the first ultra-high performance supercritical fluid chromatography–diode array detector (UHPSFC–DAD) assay for simultaneous quantitation…”
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Head-to-Head Comparison of Ultra-High-Performance Liquid Chromatography with Diode Array Detection versus Quantitative Nuclear Magnetic Resonance for the Quantitative Analysis of the Silymarin Complex in Silybum marianum Fruit Extracts
Published in Journal of agricultural and food chemistry (24-02-2016)“…Quantitative nuclear magnetic resonance (qNMR) spectroscopy is known as an excellent alternative to chromatography-based mixture analysis. NMR spectroscopy is…”
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Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation
Published in Clinica chimica acta (01-02-2019)“…Metabolomics is a well-established field in fundamental clinical research with applications in different human body fluids. However, metabolomic investigations…”
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Comprehensive polyphenolic profiling in promising resistant grapevine hybrids including 17 novel breeds in northern Italy
Published in Journal of the science of food and agriculture (01-04-2021)“…BACKGROUND A promising way to overcome the susceptibility of Vitis vinifera L. to fungal diseases is the integration of genetic resistance by the interspecific…”
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