Search Results - "STUDER, A"
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Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited
Published in Physiological reviews (01-01-2015)“…Transcription and translation require a high concentration of potassium across the entire tree of life. The conservation of a high intracellular potassium was…”
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Vitellogenin underwent subfunctionalization to acquire caste and behavioral specific expression in the harvester ant Pogonomyrmex barbatus
Published in PLoS genetics (01-08-2013)“…The reproductive ground plan hypothesis (RGPH) proposes that the physiological pathways regulating reproduction were co-opted to regulate worker division of…”
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Transformation cycle between the spherically symmetric correlation function, projected correlation function and differential cross section as implemented in SASfit
Published in Journal of applied crystallography (01-10-2017)“…Spin‐echo‐based small‐angle neutron scattering techniques like spin‐echo SANS (SESANS) or spin‐echo modulated SANS (SEMSANS) as well as dark‐field (DF) imaging…”
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Stability-activity tradeoffs constrain the adaptive evolution of RubisCO
Published in Proceedings of the National Academy of Sciences - PNAS (11-02-2014)“…A well-known case of evolutionary adaptation is that of ribulose-1,5-bisphosphate carboxylase (RubisCO), the enzyme responsible for fixation of CO ₂ during…”
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Origin of the response to adrenal and sex steroids: Roles of promiscuity and co-evolution of enzymes and steroid receptors
Published in The Journal of steroid biochemistry and molecular biology (01-07-2015)“…•Adrenal and sex steroid receptors first appear in an ancestral chordate.•Cyclostome clade (lampreys and hagfish) contain an ER, PR and CR.•There was multiple…”
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Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes
Published in Biochemical journal (01-02-2013)“…The present review focuses on the evolution of proteins and the impact of amino acid mutations on function from a structural perspective. Proteins evolve under…”
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Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs
Published in PLoS computational biology (01-05-2012)“…The function of most proteins is not determined experimentally, but is extrapolated from homologs. According to the "ortholog conjecture", or standard model of…”
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How confident can we be that orthologs are similar, but paralogs differ?
Published in Trends in genetics (01-05-2009)“…Homologous genes are classified into orthologs and paralogs, depending on whether they arose by speciation or duplication. It is widely assumed that orthologs…”
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Parasites and global warming: net effects of temperature on an intertidal host–parasite system
Published in Marine ecology. Progress series (Halstenbek) (29-09-2010)“…Climate changes, particularly global warming, are likely to impact host–parasite interactions. However, our understanding of the effects of environmental…”
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Evolution of protein phosphorylation across 18 fungal species
Published in Science (American Association for the Advancement of Science) (14-10-2016)“…Living organisms have evolved protein phosphorylation, a rapid and versatile mechanism that drives signaling and regulates protein function. We report the…”
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New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
Published in Nucleic acids research (01-01-2013)“…CATH version 3.5 (Class, Architecture, Topology, Homology, available at http://www.cathdb.info/) contains 173 536 domains, 2626 homologous superfamilies and…”
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Conserved phosphorylation hotspots in eukaryotic protein domain families
Published in Nature communications (29-04-2019)“…Protein phosphorylation is the best characterized post-translational modification that regulates almost all cellular processes through diverse mechanisms such…”
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Intra- versus intermolecular electron transfer in radical nucleophilic aromatic substitution of dihalo(hetero)arenes - a tool for estimating π-conjugation in aromatic systems
Published in Chemical science (Cambridge) (01-05-2017)“…In this paper, the application of the double radical nucleophilic aromatic substitution (S 1) in various dihalogenated, mostly diiodinated, π-conjugated…”
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Analysis of trait mean and variability versus temperature in trematode cercariae: is there scope for adaptation to global warming?
Published in International journal for parasitology (01-05-2014)“…•Analysis of trematode trait means and variability in relation to temperature.•Traits assessed: output, survival and infectivity of cercariae.•Means follow…”
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Effects of salinity on an intertidal host–parasite system: Is the parasite more sensitive than its host?
Published in Journal of experimental marine biology and ecology (31-01-2012)“…Intertidal habitats are characterised by highly fluctuating environmental conditions including varying salinity regimes. Changes in salinity may be gradual or…”
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Seasonal dynamics in an intertidal mudflat: the case of a complex trematode life cycle
Published in Marine ecology. Progress series (Halstenbek) (30-05-2012)“…Seasonal fluctuations of host densities and environmental factors are common in many ecosystems and have consequences for biotic interactions, such as the…”
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The effect of cold-rolling on the microstructure and corrosion behaviour of 316L alloy in FLiNaK molten salt
Published in Corrosion science (01-09-2018)“…[Display omitted] •Cold-rolling leads to increased amounts of grain boundaries and dislocations.•Cold-rolling increases the susceptibly of 316L alloy to…”
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The Impact of Incomplete Nutrient Consumption in the Southern Ocean on Global Mean Ocean Nitrate δ15N
Published in Global biogeochemical cycles (01-02-2023)“…It is understood that the global mean ocean nitrate δ15N is set by the δ15N of the input of fixed nitrogen (N) to the ocean (mostly N2 fixation) and the net…”
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Cercarial survival in an intertidal trematode: a multifactorial experiment with temperature, salinity and ultraviolet radiation
Published in Parasitology research (1987) (2013)“…Parasite transmission takes place in the context of a multitude of simultaneously fluctuating environmental factors. As a particularly vulnerable step in the…”
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