Search Results - "STROHFELDT, K"
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Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo
Published in British journal of cancer (05-11-2007)“…Titanocene compounds are a novel series of agents that exhibit cytotoxic effects in a variety of human cancer cells in vitro and in vivo. In this study, the…”
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Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells
Published in Apoptosis (London) (01-07-2006)“…Advanced prostate cancer is not curable by current treatment strategies indicating a significant need for new chemotherapeutic options. Highly substituted…”
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3
3-Silaoxetane and 3-silathietane: structure and reactivity studies on the basis of spectroscopic data and theoretical calculations
Published in Inorganica Chimica Acta (20-04-2004)“…Raman spectra were obtained from 3-silaoxetane 3,3-dimethyl-2,2,4,4-tetraphenyl-1-oxa-3-silacyclobutane ( 1) and 3-silathietane…”
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4
Novel benzyl substituted titanocene anti-cancer drugs
Published in Journal of organometallic chemistry (01-11-2005)“…Bis-[( p-methoxybenzyl)cyclopentadienyl]titanium (IV) dichloride is a promising candidate for an anti-cancer drug and was synthesised starting from 6-(…”
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5
The Crystal Structures of the Chiral Alkyllithium Bases [n-BuLi·(−)-Sparteine]2 and [Et2O·(i-PrLi)2·(−)-Sparteine]
Published in Journal of the American Chemical Society (12-11-2003)“…The crystal structures of the two chiral alkyllithium bases [n-BuLi·(−)-sparteine]2 (1) and [Et2O·(i-PrLi)2·(−)-sparteine] (2) have been determined. For…”
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6
[tBuLi⋅(−)-Sparteine]: Molecular Structure of the First Monomeric Butyllithium Compound
Published in Angewandte Chemie International Edition (29-09-2003)“…A chiral butyllithium reagent: Monomeric [tBuLi⋅(−)‐sparteine] crystallizes from a solution in n‐pentane on cooling. At the lithium center of the compound a…”
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7
In-vitro anti-tumor activity studies of bridged and unbridged benzyl-substituted titanocenes
Published in Anti-cancer drugs (01-11-2005)“…The benzyl-substituted ansa-titanocenes [1,2-di(cyclopentadienyl)-1,2-di-(4-N,N-dimethylaminophenyl)ethanediyl] titanium dichloride (Titanocene X) and…”
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8
Crystal Structures of (+)-Sparteine Surrogate Adducts of Methyllithium and Phenyllithium
Published in Organometallics (08-11-2004)“…The crystal structures of aggregates between MeLi and PhLi and a (+)-sparteine surrogate ((+)-2) have been determined. The MeLi adduct 4 reveals a 2:2 dimer,…”
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9
Antitumour activity of [1,2-di(cyclopentadienyl)-1,2-di( p- N, N-dimethylaminophenyl)-ethanediyl] titanium dichloride in xenografted Ehrlich's ascites tumour
Published in European journal of pharmacology (18-03-2006)“…The effects of a new titanocene compound with an ansa ligand in the cyclopentadienyl rings, the 1,2-di(cyclopentadienyl)-1,2-di( p- N,…”
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10
Heteroaryl substituted ansa-titanocene anti-cancer drugs derived from fulvenes and titanium dichloride
Published in Applied organometallic chemistry (01-03-2005)“…Starting from 2‐furylfulvene (1a), 2‐thiophenylfulvene (1b), and 1‐methyl‐2‐pyrrolylfulvene (1c), [1,2‐di(cyclopentadienyl)‐1,2‐di‐(2‐furyl)ethanediyl]…”
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11
Activity of [1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride against tumor colony-forming units
Published in Anti-cancer drugs (01-11-2005)“…[1,2-di(cyclopentadienyl)-1,2-di(p-N,N-dimethylaminophenyl)-ethanediyl] titanium dichloride is a newly synthesized transition metal-based anti-cancer drug. We…”
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12
Proliferative and antiproliferative effects of titanium and iron based metallocene anticancer drugs
Published in Journal of organometallic chemistry (2009)Get full text
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13
A trimethoxyphenyl substituted ansa-titanocene: A possible anti-cancer drug
Published in Polyhedron (04-08-2005)“…The water soluble ansa-titanocene [1,2-di(cyclopentadienyl)-1,2-di-(3′,4′,5′-trimethoxyphenyl)-ethanediyl] titanium dichloride is a possible anti-cancer drug…”
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